Abstract: The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.

Abstract: The present invention relates to a method and system that allows input mammography images to be converted between domains. More particularly, the present invention relates to converting mammography images from the image style common to one manufacturer of imaging equipment to the image style common to another manufacturer of imaging equipment. Aspects and/or embodiments seek to provide a method of converting input images from the format output by one imaging device into the format normally output by another imaging device. The imaging devices may differ in their manufacturer, model or configuration such that they produce different styles of image, even if presented with the same raw input data, due to the image processing used in the imaging device(s).

Abstract: The present invention relates to deep learning implementations for medical imaging. More particularly, the present invention relates to a method and system for indicating whether additional medical tests are required after analysing an initial medical screening, in substantially real-time. Aspects and/or embodiments seek to provide a method and system for recommending additional medical tests, in substantially real-time, based on analysing an initial medical scan, with the use of deep learning.

Abstract: The present invention relates to deep learning implementations for medical imaging. More particularly, the present invention relates to a method and system for suggesting whether to obtain a second review after a first user has performed a manual review/analysis of a set of medical images from an initial medical screening. Aspects and/or embodiments seek to provide a method and system for suggesting that a second radiologist reviews one or more cases/sets of medical images in response to a first radiologist's review of the case of medical images, based on the use of computer-aided analysis (for example using deep learning) on each case/set of medical images and the first radiologist's review.

Abstract: The present invention relates to a method and system that automatically classifies tissue type/patterns and density categories in mammograms. More particularly, the present invention relates to improving the quality of assessing density and tissue pattern distribution in mammography. According to a first aspect, there is provided a computer-aided method of analysing mammographic images, the method comprising the steps of: receiving a mammogram; segmenting one or more anatomical regions of the mammogram; identifying a tissue type and a density category classification for an anatomical region; and using the identified tissue type and density category classifications to generate classifications output for the mammogram.

Abstract: The present invention relates to deep learning for automated segmentation of a medical image. More particularly, the present invention relates to deep learning for automated segmentation of anatomical regions and lesions in mammography screening and clinical assessment. According to a first aspect, there is provided a computer-aided method of segmenting regions in medical images, the method comprising the steps of: receiving input data; analysing the input data by identifying one or more regions; determining one or more characteristics for the one or more regions in the input data; and generating output segmentation data in dependence upon the characteristics for the one or more regions.

Abstract: The present invention relates to a method and system that automatically determines malignancy in mammograms in parallel with a human operator. More particularly, the present invention relates to providing a reliable automated malignancy determination in parallel to a human operator to reduce the need for two human operators in a mammography analysis workflow. Aspects and/or embodiments seek to provide a method of automatically assessing mammography data in parallel with a human operator. Aspects and/or embodiments also seek to address the problems relating to providing a substantially reliable second reader to allow a single operator to analyse and diagnose mammography data.

Abstract: The present invention relates to a method and system that allows input mammography images to be converted between domains. More particularly, the present invention relates to converting mammography images from the image style common to one manufacturer of imaging equipment to the image style common to another manufacturer of imaging equipment. Aspects and/or embodiments seek to provide a method of converting input images from the format output by one imaging device into the format normally output by another imaging device. The imaging devices may differ in their manufacturer, model or configuration such that they produce different styles of image, even if presented with the same raw input data, due to the image processing used in the imaging device(s).

Abstract: The present invention relates to deep learning implementations for medical imaging. More particularly, the present invention relates to a method and system for indicating whether additional medical tests are required after analysing an initial medical screening, in substantially real-time. Aspects and/or embodiments seek to provide a method and system for recommending additional medical tests, in substantially real-time, based on analysing an initial medical scan, with the use of deep learning.

Abstract: The present invention relates to deep learning implementations for medical imaging. More particularly, the present invention relates to a method and system for suggesting whether to obtain a second review after a first user has performed a manual review/analysis of a set of medical images from an initial medical screening. Aspects and/or embodiments seek to provide a method and system for suggesting that a second radiologist reviews one or more cases/sets of medical images in response to a first radiologist's review of the case of medical images, based on the use of computer-aided analysis (for example using deep learning) on each case/set of medical images and the first radiologist's review.

Abstract: The present invention relates to deep learning for automated assessment of malignancy of lesions. According to a first aspect, there is provided a computer-aided method of malignancy assessment of lesions, the method comprising the steps of: receiving input data; performing a first analysis on the input data to identify one or more lesions, generating a probability map for the one or more lesions from the input data; performing a second analysis on the input data to obtain a malignancy probability mask for the input data; and generating an overlay for the input data by combining the lesion probability map with the malignancy probability mask.

Abstract: The present invention relates to a method and system that automatically determines malignancy in mammograms in parallel with a human operator. More particularly, the present invention relates to providing a reliable automated malignancy determination in parallel to a human operator to reduce the need for two human operators in a mammography analysis workflow. Aspects and/or embodiments seek to provide a method of automatically assessing mammography data in parallel with a human operator. Aspects and/or embodiments also seek to address the problems relating to providing a substantially reliable second reader to allow a single operator to analyse and diagnose mammography data.

Abstract: The present invention relates to deep learning for automated assessment of malignancy of lesions. According to a first aspect, there is provided a computer-aided method of malignancy assessment of lesions, the method comprising the steps of: receiving input data; performing a first analysis on the input data to identify one or more lesions, generating a probability map for the one or more lesions from the input data; performing a second analysis on the input data to obtain a malignancy probability mask for the input data; and generating an overlay for the input data by combining the lesion probability map with the malignancy probability mask.

Abstract: The present invention relates to deep learning for automated segmentation of a medical image. More particularly, the present invention relates to deep learning for automated segmentation of anatomical regions and lesions in mammography screening and clinical assessment. According to a first aspect, there is provided a computer-aided method of segmenting regions in medical images, the method comprising the steps of: receiving input data; analysing the input data by identifying one or more regions; determining one or more characteristics for the one or more regions in the input data; and generating output segmentation data in dependence upon the characteristics for the one or more regions.

Abstract: The present invention relates to a method and system that automatically classifies tissue type/patterns and density categories in mammograms. More particularly, the present invention relates to improving the quality of assessing density and tissue pattern distribution in mammography. According to a first aspect, there is provided a computer-aided method of analysing mammographic images, the method comprising the steps of: receiving a mammogram; segmenting one or more anatomical regions of the mammogram; identifying a tissue type and a density category classification for an anatomical region; and using the identified tissue type and density category classifications to generate classifications output for the mammogram.

Abstract: A pipe reduction piece (10) made from plastic material, having an interior volume (12) that is provided for being flowed through by a fluid in a predetermined flow direction, wherein the pipe reduction piece (10) is formed from a first section (14) and a second section (16), said sections having interior walls (18, 20) adjoining one another in a flush manner, wherein the interior wall (18) of the first section (14) delimits a first cylindrically configured partial volume (22) of the interior volume (12), and wherein the interior wall (20) of the second section (16) delimits a second partial volume (24) of the interior volume (12), the second partial volume being configured with a decreasing cross-sectional surface in the direction of the first partial volume (22).

Abstract: The invention relates to a pipe reduction piece (10) made from plastic material, having an interior volume (12) that is provided for being flowed through by a fluid in a predetermined flow direction, wherein the pipe reduction piece (10) is formed from a first section (14) and a second section (16), said sections having interior walls (18, 20) adjoining one another in a flush manner, wherein the interior wall (18) of the first section (14) delimits a first cylindrically configured partial volume (22) of the interior volume (12), and wherein the interior wall (20) of the second section (16) delimits a second partial volume (24) of the interior volume (12), said second partial volume being configured with a decreasing cross-sectional surface in the direction of the first partial volume (22).