Abstract: The invention provides agents and methods for treating bacterial infections using RNA. The RNA encoding peptidoglycan hydrolases. e.g., endolysins, is formulated and administered in a way that peptidoglycan hydrolase proteins. e.g., endolysin proteins, can be produced and secreted by cells of a subject to combat bacterial infections.

Abstract: The present invention relates to a microneedle system (MNS for short) for the intradermal application of a hepatitis vaccine, namely the antigen HBsAg.

Abstract: A mold element, in particular a casting mold for manufacturing microstructures, in particular microneedle arrays, includes a base body. On an upper side of the base body, several depressions for receiving material for manufacturing the microstructure are provided. In order to improve the quality of the microstructure to be manufactured, in particular during a drying process, channels are provided on the upper side of the base body, each of which is connected to at least one of the depressions.

Abstract: The present invention relates to a microneedle system (MNS) for the intradermal delivery of interferon, wherein polyvinylpyrrolidone is the major constituent of a completely soluble formulation.

Abstract: A carrier element for micro-needles for forming a micro-needle array has a plate-like base element. Mounting elements for respectively connecting to a micro-needle of the micro-needle array are provided on a front side of the base element. Connecting elements are also provided, in particular on the front side of the mounting elements. The connecting elements are formed in such a way that they have an undercut in the longitudinal direction such that the needles are reliably connected to the mounting elements.

Abstract: The invention relates to a microneedle array and to the use thereof for intradermal delivery, comprising a plurality of microneedles on a carrier, wherein this microneedle array is suitable for penetrating the skin of humans or animals and includes at least one color change indicator.

Abstract: Systems and methods for detecting inclement weather in the vicinity of an aircraft engine are described herein. At least a first engine parameter and a second engine parameter are obtained, each engine parameter varies with changing weather conditions. An arithmetic value is determined as a function of at least the first engine parameter and the second engine parameter. The arithmetic value varies with changing weather conditions. A rate of change of the arithmetic value is determined. Inclement weather is detected when the rate of change exceeds a threshold.

Abstract: The invention relates to a connector for connecting a first solar cell electrode to a further element, wherein the connector has a metallic conductor structure and the conductor structure is coated along the periphery thereof alternately in a circumferential manner with two respective continuous areas of materials A and B, wherein A is a solder material and B is a dielectric material, characterized in that the surface area of each orthogonal projection of the entire connector is at least 10% larger than the surface area of the orthogonal projection of each of the areas of material A. The invention further relates to a method for producing the connector and to a photovoltaic component containing the connector according to the invention.

Abstract: The present disclosure is directed to apparatuses and methods for diagnosing a swallowing dysfunction. The apparatus may include a multi-parametric dysphagia analysis system in a plastic foil. The analysis systems may be smart sensing systems that are flexible, lightweight, and based on substrates having low-cost printed electronics technologies thereon. The methods may include measurement and classification of non-invasive parameters that may be indicative of a swallowing dysfunction or the probability of same. In a general embodiment, the methods include placing a sensor on a patient for measurement of at least one parameter associated with the patient's swallowing profile. The measured parameter is then analyzed and compared with several known normal and dysphagic swallowing profiles to provide an indication of the probability of an underlying swallowing dysfunction.

Abstract: Systems and methods for detecting inclement weather in the vicinity of an aircraft engine are described herein. At least a first engine parameter and a second engine parameter are obtained, each engine parameter varies with changing weather conditions. An arithmetic value is determined as a function of at least the first engine parameter and the second engine parameter. The arithmetic value varies with changing weather conditions. A rate of change of the arithmetic value is determined. Inclement weather is detected when the rate of change exceeds a threshold.

Abstract: The present disclosure is directed to apparatuses and methods for diagnosing a swallowing dysfunction. The apparatuses may include a multi-parametric dysphagia analysis system in a plastic foil. The analysis systems may be smart sensing systems that are flexible, lightweight, and based on substrates having low-cost printed electronics technologies thereon. The methods may include measurement and classification of non-invasive parameters that may be indicative of a swallowing dysfunction or the probability of same. In a general embodiment, the methods include placing a sensor on a patient for measurement of at least one parameter associated with the patient's swallowing profile. The measured parameter is then analyzed and compared with several known normal and dysphagic swallowing profiles to provide an indication of the probability of an underlying swallowing dysfunction.

Abstract: The present invention relates to a connector for connecting a solar cell electrode to a further element, whereby the connector comprises a conductor pattern on which at least one metallic coating is arranged, whereby the conductor pattern contains aluminium, characterised in that the coating contains an element selected from the group consisting of Ni, Ag, Sn, Pb, Zn, Bi, In, Sb, Co, Cr as well as alloys of said elements.

Abstract: A belt retractor has a frame (10), a belt spool (12) that is rotatably mounted in the frame (10), and a force limiter (22) that is adapted to reach a force limiting position. A guide-in mechanism (26) is provided which causes the force limiter (22) to reach the force limiting position as a function of the length of belt webbing withdrawn.

Abstract: The present disclosure is directed to apparatuses and methods for diagnosing a swallowing dysfunction. The apparatuses may include a multi-parametric dysphagia analysis system in a plastic foil. The analysis systems may be smart sensing systems that are flexible, lightweight, and based on substrates having low-cost printed electronics technologies thereon. The methods may include measurement and classification of non-invasive parameters that may be indicative of a swallowing dysfunction or the probability of same. In a general embodiment, the methods include placing a sensor on a patient for measurement of at least one parameter associated with the patient's swallowing profile. The measured parameter is then analyzed and compared with several known normal and dysphagic swallowing profiles to provide an indication of the probability of an underlying swallowing dysfunction.

Abstract: A front-axle bracket for motor vehicles has two accommodations spaced apart from one another in the longitudinal vehicle direction in each instance for the bearing locations for pivoting mounting of one or two wheel guide elements, in each instance, such as transverse control arms or A-arms, accommodations for attachment of the front-axle bracket as a pre-finished unit, together with pre-assembled assemblies, on the vehicle body, and at least individual ones of accommodations for attachment of the steering gear mechanism, for attachment of the stabilizer, and for mounting of a pendulum support. The front-axle bracket is produced as a component that is in one piece with these accommodations and connects them with one another. At least individual ones of the accommodations are integrated into the front-axle bracket by way of rod-shaped connecting elements, in framework-like manner.

Abstract: A front-axle bracket for motor vehicles has two accommodations spaced apart from one another in the longitudinal vehicle direction in each instance for the bearing locations for pivoting mounting of one of two wheel guide elements, in each instance, such as transverse control arms or A-arms, accommodations for attachment of the front-axle bracket as a pre-finished unit, together with pre-assembled assemblies, on the vehicle body, and at least individual ones of accommodations for attachment of the steering gear mechanism, for attachment of the stabilizer, and for mounting of a pendulum support. The front-axle bracket is produced as a component that is in one piece with these accommodations and connects them with one another.

Abstract: A front-axle bracket for motor vehicles has two accommodations spaced apart from one another in the longitudinal vehicle direction in each instance for the bearing locations for pivoting mounting of one or two wheel guide elements, in each instance, such as transverse control arms or A-arms, accommodations for attachment of the front-axle bracket as a pre-finished unit, together with pre-assembled assemblies, on the vehicle body, and at least individual ones of accommodations for attachment of the steering gear mechanism, for attachment of the stabilizer, and for mounting of a pendulum support. The front-axle bracket is produced as a component that is in one piece with these accommodations and connects them with one another. At least individual ones of the accommodations are integrated into the front-axle bracket by way of rod-shaped connecting elements, in framework-like manner.

Abstract: A front-axle bracket for motor vehicles has two accommodations spaced apart from one another in the longitudinal vehicle direction in each instance for the bearing locations for pivoting mounting of one of two wheel guide elements, in each instance, such as transverse control arms or A-arms, accommodations for attachment of the front-axle bracket as a pre-finished unit, together with pre-assembled assemblies, on the vehicle body, and at least individual ones of accommodations for attachment of the steering gear mechanism, for attachment of the stabilizer, and for mounting of a pendulum support. The front-axle bracket is produced as a component that is in one piece with these accommodations and connects them with one another.

Abstract: A method and a device are disclosed for automated evaluation of the quality of a software source code, a quality target being predetermined for the quality of the source code. The current quality of the source code and the distance between the current quality of the source code and the predetermined quality target are determined for the quality of the source code. At least one embodiment of the invention permits high volumes of source code to be evaluated in an automated fashion with respect to their quality.