Patents by Inventor Andreas Herling

Andreas Herling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted benzoylureido-o-benzoylamides, process for their preparation and their use
    Publication number: 20050065142
    Abstract: The invention relates to substituted benzoylureido-o-benzoylamides and to their physiologically tolerated salts and physiologically functional derivatives. The invention relates to compounds of the formula I in which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for the prevention and treatment of type 2 diabetes.
    Type: Application
    Filed: July 27, 2004
    Publication date: March 24, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Dieter Kadereit, Elisabeth Defossa, Karl Schoenafinger, Thomas Klabunde, Andreas Herling
  • Carbonylamino-substituted acyl phenyl urea derivatives, process for their preparation and their use
    Publication number: 20050014822
    Abstract: The invention relates to compounds of the formula I in which the radicals are defined as specified, and also to their physiologically tolerated salts. The compounds are suitable, for example, as medicaments for preventing and treating type 2 diabetes.
    Type: Application
    Filed: January 23, 2004
    Publication date: January 20, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Elisabeth Defossa, Dieter Kadereit, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Karl Schoenafinger, Alfons Enhsen
  • Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use
    Publication number: 20040266768
    Abstract: The invention relates to compounds of the formula I 1
    Type: Application
    Filed: March 8, 2004
    Publication date: December 30, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Karl Schoenafinger, Dieter Kadereit, Elisabeth Defossa, Andreas Herling, Thomas Klabunde
  • Carboxamide-substituted phenylurea derivatives, process for their preparation and their use as medicaments
    Patent number: 6812250
    Abstract: The invention relates to carboxamide-substituted phenylurea derivatives and their physiologically tolerated salts and physiologically functional derivatives. Compounds of the formula I in which the radicals have the stated meanings, and the physiologically tolerated salts thereof and process for their preparation are described. The compounds are suitable, for example, for treating type II diabetes.
    Type: Grant
    Filed: May 24, 2002
    Date of Patent: November 2, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Elisabeth Defossa, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Erich von Roedern, Stefan Peukert, Alfons Enhsen, Armin Bauer, Bernd Neises, Karl Ulrich Wendt
  • Substituted 3-(benzoylureido) thiophene derivatives, processes for preparing them and their use
    Publication number: 20040198742
    Abstract: Substituted 3-(benzoylureido)thiophene derivatives, processes for preparing them and their use
    Type: Application
    Filed: February 17, 2004
    Publication date: October 7, 2004
    Applicant: AVENTIS PHARMA DEUTSCHLAND GMBH
    Inventors: Karl Schoenafinger, Elisabeth Defossa, Erich Von Roedern, Dieter Kadereit, Andreas Herling, Hans-Joerg Burger, Thomas Klabunde, Karl-Ulrich Wendt
  • Carboxyalkoxy-substituted acyl-carboxyphenylurea derivatives and their use as medicaments
    Publication number: 20040157922
    Abstract: Carboxyalkoxy-substituted acyl-carboxyphenylurea derivatives and their use as medicaments
    Type: Application
    Filed: October 6, 2003
    Publication date: August 12, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Elisabeth Defossa, Dieter Kadereit, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Karl Schoenafinger, Alfons Enhsen
  • Heterocyclically substituted benzoylureas, process for their preparation and their use as pharmaceuticals
    Publication number: 20040152743
    Abstract: The invention relates to heterocyclically substituted benzoylureas and also to their physiologically tolerated salts and physiologically functional derivatives.
    Type: Application
    Filed: July 11, 2003
    Publication date: August 5, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Karl Schoenafinger, Elisabeth Defossa, Dieter Kadereit, Erich Von Roedern, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt
  • Novel adenosine analogues and their use as pharmaceutical agents
    Publication number: 20040127434
    Abstract: The present invention relates to compounds according to the general formula (I) 1
    Type: Application
    Filed: June 27, 2003
    Publication date: July 1, 2004
    Inventors: Antony Bigot, Siegfried Stengelin, Gerhard Jaehne, Andreas Herling, Guenter Mueller, Franz Jakob Hock, Michael R. Myers
  • N-benzoylureidocinnamic acid derivatives, processes for preparing them and their use
    Publication number: 20040102518
    Abstract: The invention relates to N-benzoylureidocinnamic acid derivatives and to their physiologically tolerated salts and physiologically functional derivatives.
    Type: Application
    Filed: June 6, 2003
    Publication date: May 27, 2004
    Applicant: Aventis Pharma AG
    Inventors: Karl Schoenafinger, Elisabeth Defossa, Dieter Kadereit, Erich Von Roedern, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt
  • Urea- and urethane-substituted acylureas, process for their preparation and their use
    Publication number: 20040087659
    Abstract: The invention relates to urea- and urethane-substituted acylureas and to their physiologically tolerated salts and physiologically functional derivatives.
    Type: Application
    Filed: July 11, 2003
    Publication date: May 6, 2004
    Inventors: Elisabeth Defossa, Dieter Kadereit, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Karl Schoenafinger
  • Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use
    Publication number: 20040077716
    Abstract: The invention relates to acyl-4-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives.
    Type: Application
    Filed: April 10, 2003
    Publication date: April 22, 2004
    Inventors: Elisabeth Defossa, Dieter Kadereit, Karl Schoenafinger, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Alfons Enhsen, Joerg Rieke-Zapp
  • Acyl-3-carboxyphenylurea derivatives, processes for preparing them and their use
    Publication number: 20030216370
    Abstract: The invention relates to acyl-3-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives.
    Type: Application
    Filed: April 10, 2003
    Publication date: November 20, 2003
    Inventors: Elisabeth Defossa, Dieter Kadereit, Karl Schoenafinger, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Alfons Enhsen
  • Methods of treating insulin resistance syndrome and diabetes
    Publication number: 20030176390
    Abstract: This invention is directed to methods of treating insulin resistance syndrome and diabetes in a patient in need thereof, comprising administering to said patient a pharmaceutically effective amount of a compound derived from adenosine and analogues thereof, or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable prodrug thereof, an N-oxide thereof, a hydrate thereof or a solvate thereof, or a pharmaceutical composition comprising such compound.
    Type: Application
    Filed: May 14, 2002
    Publication date: September 18, 2003
    Inventors: Andreas Herling, Gerhard Jaehne, Martin P. Maguire, Alfred P. Spada, Michael R. Myers, Yong Mi Choi-Sledeski, Heinz W. Pauls, William R. Ewing
  • Carboxamide-substituted phenylurea derivatives, process for their preparation and their use as medicaments
    Publication number: 20030176497
    Abstract: The invention relates to carboxamide-substituted phenylurea derivatives and their physiologically tolerated salts and physiologically functional derivatives.
    Type: Application
    Filed: May 24, 2002
    Publication date: September 18, 2003
    Inventors: Elisabeth Defossa, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Erich von Roedern, Stefan Peukert, Alfons Enhsen, Armin Bauer, Bernd Neises, Karl Ulrich Wendt
  • Acylphenylurea derivatives, a process for their preparation and their use as pharmaceuticals
    Patent number: 6506778
    Abstract: The invention is directed to acylphenylurea derivatives and their physiologically tolerated salts and physiologically functional derivatives. Compounds of the formula I in which the radicals have the stated meanings, and their physiologically tolerated salts and a process for their preparation are described. The compounds are suitable, for example, for treating type II diabetes.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: January 14, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Elisabeth Defossa, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Heinz Baringhaus
  • Acylphenylurea derivatives, a process for their preparation and their use as pharmaceuticals
    Publication number: 20020151586
    Abstract: The invention is directed to acylphenylurea derivatives and their physiologically tolerated salts and physiologically functional derivatives.
    Type: Application
    Filed: June 8, 2001
    Publication date: October 17, 2002
    Inventors: Elisabeth Defossa, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Heinz Baringhaus
  • Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them
    Patent number: 6191164
    Abstract: Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or a diagnostic, and medicament comprising them Chromans of the formula I and of the formula 1a having the meanings R(A), R(B), R(C) and R(1) to R(8) indicated in the claims are outstandingly suitable for preparing a medicament for blocking the K+ channel which is opened by cyclic adenosine monophosphate (cAMP); and further for preparing a medicament for inhibiting gastric acid secretion; for the treatment of ulcers of the stomach and of the intestinal region, in particular of the duodenum, for the treatment of reflux esophagitis, for the treatment of diarrheal illnesses, for the treatment and prevention of all types of arrhythmias including ventricular and supraventricular arrhythmias, and for the control of reentry arrhythmias and for the prevention of sudden heart death as a result of ventricular fibrillation.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: February 20, 2001
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Jochen Lang, Uwe Gerlach, Joachim Brendel, Henrich Christian Englert, Heinz Gögelein, Max Hropot, Helmut Bohn, Andreas Herling, Andreas Busch, Rainer Greger
  • Kodaistatins A, B, C and D, a process for their production and their use
    Patent number: 6166070
    Abstract: Kodaistatins A and B, compounds of the molecular formula C.sub.35 H.sub.34 O.sub.11, and Kodaistatins C and D, compounds of the molecular formula C.sub.35 H.sub.34 O.sub.12, have antidiabetic activity.
    Type: Grant
    Filed: October 18, 1999
    Date of Patent: December 26, 2000
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Nirogi Venkata Satya Ramakrishna, Keshavapura Hosamane Sreedhara Swamy, Erra Koreswara Satya Vijayakumar, Suresh Rudra Nadkarni, Kenia Jayvanti, Andreas Herling, Herbert Kogler, Laszlo Vertesy, Rajan Mukund Panshikar, Kota Sridevi, Mythili Raman, Roda Maneck Dalal
  • Substituted propane derivatives, a process for their preparation and the use of the compounds for treating diseases
    Patent number: 5767141
    Abstract: Substituted propane derivatives, a process for their preparation and the use of the compounds for treating diseasesPropane derivatives of the formula I ##STR1## in which the radicals have the meanings stated in the description, a process for the preparation of these compounds, their use as pharmaceuticals, and pharmaceutical products are described. Also described are novel intermediates for preparing the compounds of the formula I.
    Type: Grant
    Filed: March 8, 1995
    Date of Patent: June 16, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerrit Schubert, Horst Hemmerle, Peter Below, Andreas Herling, Hans-Jorg Burger
  • Cyclohexane derivatives, process for their preparation, and the use of the compounds for the treatment of diseases
    Patent number: 5739147
    Abstract: Cyclohexane derivatives, process for their preparation, and the use of the compounds for the treatment of diseasesCyclohexane derivatives of the formula I ##STR1## wherein R.sup.2, R.sup.4 and R.sup.5 have the given meanings and a process for their preparation are described. The compounds have useful pharmacological properties and can therefore be used as pharmaceuticals.
    Type: Grant
    Filed: May 21, 1997
    Date of Patent: April 14, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Horst Hemmerle, Gerrit Schubert, Hans-Jorg Burger, Andreas Herling, Suad Efendic'