Abstract: Disclosed is an optoelectromechanical switch that includes: an optical feedline disposed on an isolation substrate that receives resonator light that is subject to optical communication to a resonator when a cavity length of the resonator supports an electromagnetic mode at the wavelength of the resonator light; a resonator including: a low refractive index optical layer and receives substrate electrical counter potential; a non-conductive spacer; the electrically conductive membrane and that receives a membrane electrical potential and deflects toward and away from the electrically conductive high-index optical waveguide based on a difference in potential between the membrane electrical potential and the substrate electrical counter potential; the cavity length that is variable and under electromechanical control.

Abstract: The invention relates to a process for removing dienes from a material stream comprising C3 to C5 hydrocarbons by selective hydrogenation at a specified reaction pressure and a specified reaction temperature in the presence of a hydrogenation catalyst, wherein the reaction pressure and the reaction temperature at the reactor inlet are regulated such that the reaction pressure at the reactor inlet does not deviate by more than 0.01 bar from the specified reaction pressure and the reaction temperature at the reactor inlet does not deviate by more than 0.1° C. from the specified reaction temperature and the proportion of hydrogen supplied to the selective hydrogenation is in the range from 2 to 20 moles per mole of diene present in the material stream comprising C3 to C5 hydrocarbons.

Abstract: Disclosed is an optoelectromechanical switch that includes: an optical feedline disposed on an isolation substrate that receives resonator light that is subject to optical communication to a resonator when a cavity length of the resonator supports an electromagnetic mode at the wavelength of the resonator light; a resonator including: a low refractive index optical layer and receives substrate electrical counter potential; a non-conductive spacer; the electrically conductive membrane and that receives a membrane electrical potential and deflects toward and away from the electrically conductive high-index optical waveguide based on a difference in potential between the membrane electrical potential and the substrate electrical counter potential; the cavity length that is variable and under electromechanical control.

Abstract: The present invention relates to a pharmaceutical combination comprising an FGFR4 inhibitor and a bile acid sequestrant, to the use of the pharmaceutical combination in the treatment of cancer, to the use of a bile acid sequestrant to reduce or mitigate side-effects associated with FGFR4 inhibition therapy.

Abstract: The invention relates to a process for removing dienes from a material stream comprising C3 to C5 hydrocarbons by selective hydrogenation at a specified reaction pressure and a specified reaction temperature in the presence of a hydrogenation catalyst, wherein the reaction pressure and the reaction temperature at the reactor inlet are regulated such that the reaction pressure at the reactor inlet does not deviate by more than 0.01 bar from the specified reaction pressure and the reaction temperature at the reactor inlet does not deviate by more than 0.1° C. from the specified reaction temperature and the proportion of hydrogen supplied to the selective hydrogenation is in the range from 2 to 20 moles per mole of diene present in the material stream comprising C3 to C5 hydrocarbons.

Abstract: Process for the preparation of alpha, beta unsaturated aldehydes by oxidation of alcohols in the presence of a liquid phase wherein the liquid phase contains 0.1 to less than 25 weight-% water and wherein the liquid phase contains at least 25 weight-% of alcohol(s) of general formula (II) and alpha, beta unsaturated aldehyde(s) of general formula (I) and wherein the oxidant is oxygen and/or hydrogen peroxide.

Abstract: The present invention relates to a pharmaceutical combination comprising an FGFR4 inhibitor and a bile acid sequestrant, to the use of the pharmaceutical combination in the treatment of cancer, to the use of a bile acid sequestrant to reduce or mitigate side-effects associated with FGFR4 inhibition therapy.

Abstract: The present invention provides a catalyst comprising alumina as carrier material and palladium or platinum as active component, obtainable by a) impregnating an alumina carrier with a solution comprising at least one salt of the active component palladium or platinum, b) drying the catalyst thus obtained, c) treating the catalyst thus obtained with hydrogen, or a mixture of hydrogen and at least one inert gas, for a period of 1 to 24 hours at a temperature of 30 to 200° C., and d) thereafter keeping the catalyst thus reduced in the presence of hydrogen, or a mixture of hydrogen and at least one inert gas, for a period of 1 hour to 10 days at a temperature of 10 to 100° C. The catalyst provided by the invention is useful in processes for isomerization of olefins from olefin-containing hydrocarbonaceous mixtures having 4 to 20 carbon atoms at temperatures of 10 to 150° C. and pressures of 1 to 35 bar.

Abstract: The invention relates to a method of fast identification and isolation of cells featuring a desired phenotype. The phenotype is coupled to the amount of gas-liberating enzymes or increased growth. The cells are encapsulated into microcapsules allowing exchange of solvents through the microcapsule wall, but retaining some or all of the gas formed by gas-liberating enzymes on contact with corresponding substrates. Microcapsules containing increased amounts of gas-liberating enzymes are starting to float and can be separated. The cells are then isolated from the microcapsules according to standard procedures.

Abstract: The invention relates to a method of fast identification and isolation of cells featuring a desired phenotype. The phenotype is coupled to the amount of gas-liberating enzymes or increased growth. The cells are encapsulated into microcapsules allowing exchange of solvents through the microcapsule wall, but retaining some or all of the gas formed by gas-liberating enzymes on contact with corresponding substrates. Microcapsules containing increased amounts of gas-liberating enzymes are starting to float and can be separated. The cells are then isolated from the microcapsules according to standard procedures.

Abstract: An over-center self adjusting cap chuck adapted for operative attachment to a high-speed capping machine includes a housing having an outer peripheral surface defining an inner annular periphery with an interior face. A plurality of independent engagement jaws are aligned along an annular area of, or within a pocket area of, the interior face. Each engagement jaw has a fastener to connect the engagement jaw to the housing and establish a pivot point to support a limited axial rotational movement thereof to a first open axial position and a second closed axial position for receiving and gripping a work piece respectively. Either a singular bias spring or a pair of bias springs pre-dispose the engagement jaws to the first open axial position.

Abstract: The combing machine comprises a nipper unit possessing a bottom nipper and a top nipper which is pivotable relative to the bottom nipper about a pivot axle. An additional nipper is pivotable relative to the bottom nipper about a shaft or journal which extends at a suitable distance from and substantially parallel to the pivot axle of the top nipper. The additional nipper is coupled to the top nipper by means of at least one link. In this manner, pivoting movements of the top nipper cause the additional nipper to be pivoted each time in the opposite direction with respect to the direction of motion of the bottom nipper. When the nipper unit is in an advanced end position, the top nipper is open and the additional nipper is closed. The additional nipper firmly holds the lap, and a tuft combed out of the latter is detached by a detaching roll. No separate pivot drive is required for the additional nipper.