Patents by Inventor Andreas Kiener

Andreas Kiener has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microbiological process for the production of 6-hydroxynicotinic acid
    Patent number: 5264362
    Abstract: A microbiological process for the production of 6-hydroxynicotinic acid starting from 3-cyanopyridine. For this process, new microorganisms are used, which are capable of growing with 3-cyanopyridine as the sole carbon, nitrogen and energy source and of biotransforming it as substrate in 6-hydroxynicotinic acid.
    Type: Grant
    Filed: October 14, 1992
    Date of Patent: November 23, 1993
    Assignee: Lonza Ltd.
    Inventor: Andreas Kiener
  • Microbiological oxidation of alkyl groups in heterocycles
    Patent number: 5242816
    Abstract: A microbiological process for the terminal oxidation of alkyl groups in 5- or 6-ring heterocycles which are substituted with at least one alkyl group with more than 2 carbon atoms to carboxylic acids.
    Type: Grant
    Filed: July 3, 1991
    Date of Patent: September 7, 1993
    Assignee: Lonza Ltd.
    Inventor: Andreas Kiener
  • Microbiological process for the production of 6-hydroxypicolinic acid
    Patent number: 5238830
    Abstract: A microbiological process for the production of 6-hydroxypicolinic acid starting from picolinic acid and/or its salts. The concentration of picolinic acid and/or its salts is selected so that the 6-hydroxypicolinic acid is not further metabolized. The process is performed either by microorganisms of genus Pseudomonas, Bacillus, Alcalioenes, Aerococcus, or Rhodotorula, or with biomass using picolinic acid, which grow with picolinic acid as the sole carbon, nitrogen and energy source.
    Type: Grant
    Filed: March 31, 1992
    Date of Patent: August 24, 1993
    Assignee: Lonza Ltd.
    Inventors: Andreas Kiener, Rainer Glockler, Klaus Heinzmann
  • Microbiological oxidation of methyl groups in heterocycles
    Patent number: 5236832
    Abstract: A microbiological process for the oxidation of methyl groups in aromatic 5- or 6-member ring heterocycles to the corresponding carboxylic acid. The heterocycle serves as the substrate and exhibits no substituent on the carbon atoms adjacent to the methyl groups to be oxidized. The reaction of the heterocycle takes place by means of microorganisms of the genus Pseudomonas utilizing toluene, xylene, or cymene. The enzymes of the microorganisms been previously induced.
    Type: Grant
    Filed: October 30, 1991
    Date of Patent: August 17, 1993
    Assignee: Lonza, Ltd.
    Inventor: Andreas Kiener
  • Microbiological process for the production of hydroxylated heterocycles
    Patent number: 5229278
    Abstract: Microorganisms which are capable of growing with 2,5-dimethylpyrazine as the sole carbon, nitrogen and energy source. These microorganisms hydroxylate heterocycles of general formula: ##STR1## to heterocycles of general formula: ##STR2## The latter compounds are accumulated in the growth medium.
    Type: Grant
    Filed: September 24, 1991
    Date of Patent: July 20, 1993
    Assignee: Lonza Ltd.
    Inventors: Andreas Kiener, Yvonne V. Gameren, Michael Bokel
  • Hydroxylation of methyl groups in aromatic heterocycles by microorganisms
    Patent number: 5217884
    Abstract: A process using microorganisms which contain genes, which form an active xylene monooxygenase, which form no effective, chromosomally or plasmid-coded alcohol hydrogenase, and which are, thus, capable of hydroxylating methyl groups on aromatic 5- or 6-atom heterocycles to the corresponding hydroxymethyl derivatives, for the production of hydroxymethylated 5- or 6-atom heterocycles.
    Type: Grant
    Filed: September 23, 1991
    Date of Patent: June 8, 1993
    Assignee: Lonza Ltd.
    Inventors: Thomas Zimmermann, Andreas Kiener, Shigeaki Harayama
  • Microbiological process for the production of 6-hydroxypicolinic acid
    Patent number: 5182197
    Abstract: A microbiological process for the production of 6-hydroxypicolinic acid starting from picolinic acid and/or its salts. The concentration of picolinic acid and/or its salts is selected so that the 6-hydroxypicolinic acid is not further metabolized. The process is performed either by microorganisms of genus Pseudomonas, Bacillus, Alcaligenes, Aerococcus, or Rhodotorula, or with biomass using picolinic acid, which grow with picolinic acid as the sole carbon, nitrogen and energy source.
    Type: Grant
    Filed: February 4, 1992
    Date of Patent: January 26, 1993
    Assignee: Lonza Ltd.
    Inventors: Andreas Kiener, Rainer Glockler, Klaus Heinzmann
  • Microbiological process for the production of hydroxylated pyrazine derivatives
    Patent number: 5173412
    Abstract: Microorganisms, which are capable of growing with pyrazine as the sole carbon, nitrogen and energy source. These microorganisms hydroxylate pyrazine derivatives of general formula: ##STR1## to hydroxylated pyrazine derivatives of general formula: ##STR2## and the latter are accumulated in the growth medium.
    Type: Grant
    Filed: November 6, 1991
    Date of Patent: December 22, 1992
    Assignee: Lonza, Ltd.
    Inventors: Andreas Kiener, Klaus Heinzmann, Michael Bokel
  • Microbiological oxidation of methyl groups in heterocycles
    Patent number: 5104798
    Abstract: A microbiological process for the oxidation of methyl groups in aromatic 5- or 6-member ring heterocycles to the corresponding carboxylic acid. The heterocycle serves as the substrate and exhibits no substituent on the carbon atoms adjacent to the methyl groups to be oxidized. The reaction of the heterocycle takes place by means of microorganisms of the genus Pseudomonas utilizing toluene, xylene, or cymene. The enzymes of the microorganisms have been previously induced.
    Type: Grant
    Filed: February 5, 1991
    Date of Patent: April 14, 1992
    Assignee: Lonza Ltd.
    Inventor: Andreas Kiener