Abstract: A method for monitoring a continuous industrial process is described. The industrial process includes a number of processing stations for processing material and a material flow between the number of processing stations. Each processing station dynamically provides data representing a state of the processing station. The method includes providing, for each processing station, a processing station layout of the processing station. The method further includes providing, for each processing station, an interface model of the processing station. The method further includes generating an information metamodel from the processing station layout and the interface model of the number of processing stations. The method further includes generating an adaptive simulation model of the industrial process by importing the data representing the state of the processing station provided by the number of processing stations into the adaptive simulation model via the information metamodel.

Abstract: The present invention relates to a novel method of preparing copanlisib, copanlisib dihydrochloride, or hydrates of copanlisib dihydrochloride, to novel intermediate compounds, and to the use of said novel intermediate compounds for the preparation of said copanlisib, copanlisib dihydrochloride, or hydrates of copanlisib dihydrochloride. The present invention also relates to copanlisib dihydrochloride hydrates as compounds.

Abstract: The present invention relates to a novel method of preparing copanlisib, copanlisib dihydrochloride, or hydrates of copanlisib dihydrochloride, to novel intermediate compounds, and to the use of said novel intermediate compounds for the preparation of said copanlisib, copanlisib dihydrochloride, or hydrates of copanlisib dihydrochloride. The present invention also relates to copanlisib dihydrochloride hydrates as compounds.

Abstract: The present invention relates to an improved and shortened synthesis of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acet-amide and the mesylate monohydrate salt thereof by using boronic acid derivatives or borolane reagents while avoiding toxic organic tin compounds and to the mesylate monohydrate salt of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acet-amide which has demonstrated increased long term stability and release kinetics from pharmaceutical compositions.

Abstract: The present invention relates to an improved and shortened synthesis of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acet-amide and the mesylate monohydrate salt thereof by using boronic acid derivatives or borolane reagents while avoiding toxic organic tin compounds and to the mesylate monohydrate salt of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acet-amide which has demonstrated increased long term stability and release kinetics from pharmaceutical compositions.

Abstract: The invention relates to novel substituted N-aryl nitrogen-containing heterocyclic compounds of the general formula (I) and to the compounds isomeric to the substituted N-aryl nitrogen-containing heterocyclic compounds of the formula (I), of the formulae (Ia) and (Ib) in which Q1, Q2, R1, R2 and Ar have the meanings given in the description, processes for their preparation and their use as herbicides.

Abstract: The invention relates to novel substituted N-aryl nitrogen-containing heterocyclic compounds of the general formula (I) 1

Abstract: The invention relates to novel substituted N-aryl nitrogen-containing heterocyclic compounds of the general formula (I) 1

Abstract: The present invention relates to a process for making disposable absorbent articles comprising adhering two components materials to each other using an improved roll printing process to provide an adhesive to one of the two components, the adhesive has an application temperature which is greater than a print roll temperature.

Abstract: The present invention relates to a process for making disposable absorbent articles such as sanitary napkins, panty liners, catamenials, incontinence inserts perspiration pads, and diapers for adults or babies. In particular the present invention relates to a process for the manufacture of disposable absorbent articles comprising two component materials which are adhered to each other which utilizes an improved gravure roll printing process (30) to provide the adhesive, wherein the adhesive is applied to the gravure print roll (31) such that the gravures (32) are only partly filled.

Abstract: There is disclosed substituted thiocarboxamides compounds of the formula (I): wherein R1, R2, R3 and Z are as defined in the specification. The compounds are useful as herbicides.

Abstract: The invention relates to novel substituted N-aryl nitrogen-containing heterocyclic compounds of the general formula (I) and to the compounds isomeric to the substituted N-aryl nitrogen-containing heterocyclic compounds of the formula (I), of the formulae (Ia) and (Ib) in which Q1, Q2, R1, R2 and Ar have the meanings given in the description, processes for their preparation and their use as herbicides.

Abstract: Disclosed are substituted aromatic thiocarboxamide compounds of the formula: their use as herbicides and the process of making said compounds.

Abstract: The invention relaters to compounds of the formula: and their use as herbicides.

Abstract: The invention relates to new heterocyclylbenzonitriles of the general formula (I) in which R1, R2, R3 and Het have the meanings given in the description, new processes and new intermediate products for their preparation and their use as herbicides.

Abstract: There is disclosed substituted thiocarboxamides of the general formula (I) useful as herbicides.

Abstract: The present invention relates to the use of partly known N-aryl-1,2,4-triazolin-5-ones of the formula (I) in which A, R1, R2, R3, R4 and R5 are each as defined in the description for controlling animal pests.

Abstract: The invention relates to novel arylalkyl compounds of the general formula (I) in which m represents the numbers 0 to 5, n represents the numbers 0 to 4, Q represents O, S, SO or SO2, R1 represents hydrogen or optionally substituted alkyl, R2 represents hydrogen or optionally substituted alkyl, X represents hydroxyl, mercapto, amino, hydroxyamino, nitro, formyl, carboxyl, cyano, carbamoyl, thiocarbamoyl, halogen, or represents an in each case optionally cyano-, halogen- or alkoxy-substituted radical from the series alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkylamino, dialkylamino, alkylcarbonyl or alkoxycarbonyl, Y represents nitro, carboxyl, cyano, carbamoyl, thiocarbamoyl, halogen, or represents an in each case optionally cyano-, halogen- or alkoxy-substituted radical from the series alkyl, alkoxy, alkylthio, alkylsulphinyl or alkylsulphonyl, and Z represents one of the groupings below in which R3, R4, R5, R6 and R7 are each as defined in the desc

Abstract: The invention relates to novel substituted N-aryl nitrogen-containing heterocyclic compounds of the general formula (I) ##STR1## and to the compounds isomeric to the substituted N-aryl nitrogen-containing heterocyclic compounds of the formula (I), of the formulae (Ia) and (Ib) ##STR2## in which Q.sup.1, Q.sup.2, R.sup.1, R.sup.2 and Ar have the meanings given in the description, processes for their preparation and their use as herbicides.

Abstract: There is disclosed substituted thiocarboxamides of the general formula (I) useful as herbicides.