Patents by Inventor Andreas Loehr

Andreas Loehr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230235406
    Abstract: Methods of treating a tumor in a subject and methods of determining a treatment regimen for a subject with a tumor are provided herein. In exemplary aspects, the methods comprise measuring the level of expression of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof. In exemplary aspects, the subject is a subject from which a sample was obtained, wherein the level of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof, has been measured from the sample. Related kits, computer readable-storage media, systems, and methods implemented by a processor in a computer are further provided.
    Type: Application
    Filed: September 6, 2022
    Publication date: July 27, 2023
    Applicant: Onyx Therapeutics, Inc.
    Inventors: Brian TUCH, Jeremiah DEGENHARDT, Andrea LOEHR, Kevin KWEI, Christopher J. KIRK
  • Publication number: 20210238691
    Abstract: Methods of treating a tumor in a subject and methods of determining a treatment regimen for a subject with a tumor are provided herein. In exemplary aspects, the methods comprise measuring the level of expression of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof. In exemplary aspects, the subject is a subject from which a sample was obtained, wherein the level of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof, has been measured from the sample. Related kits, computer readable-storage media, systems, and methods implemented by a processor in a computer are further provided.
    Type: Application
    Filed: December 21, 2020
    Publication date: August 5, 2021
    Inventors: Brian TUCH, Jeremiah DEGENHARDT, Andrea LOEHR, Kevin KWEI, Christopher J. KIRK
  • Patent number: 10870889
    Abstract: Methods of treating a tumor in a subject and methods of determining a treatment regimen for a subject with a tumor are provided herein. In exemplary aspects, the methods comprise measuring the level of expression of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof. In exemplary aspects, the subject is a subject from which a sample was obtained, wherein the level of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof, has been measured from the sample. Related kits, computer readable-storage media, systems, and methods implemented by a processor in a computer are further provided.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: December 22, 2020
    Assignee: Onyx Therapeutics, Inc.
    Inventors: Brian Tuch, Jeremiah Degenhardt, Andrea Loehr, Kevin Kwei, Christopher J. Kirk
  • Publication number: 20200354793
    Abstract: Methods of treating a tumor in a subject and methods of determining a treatment regimen for a subject with a tumor are provided herein. In exemplary aspects, the methods comprise measuring the level of expression of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof. In exemplary aspects, the subject is a subject from which a sample was obtained, wherein the level of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof, has been measured from the sample. Related kits, computer readable-storage media, systems, and methods implemented by a processor in a computer are further provided.
    Type: Application
    Filed: May 12, 2020
    Publication date: November 12, 2020
    Inventors: Brian Tuch, Jeremiah Degenhardt, Andrea Loehr, Kevin Kwei, Christopher J. Kirk
  • Patent number: 10662479
    Abstract: Methods of treating a tumor in a subject and methods of determining a treatment regimen for a subject with a tumor are provided herein. In exemplary aspects, the methods comprise measuring the level of expression of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof. In exemplary aspects, the subject is a subject from which a sample was obtained, wherein the level of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof, has been measured from the sample. Related kits, computer readable-storage media, systems, and methods implemented by a processor in a computer are further provided.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: May 26, 2020
    Assignee: Onyx Therapeutics, Inc.
    Inventors: Brian Tuch, Jeremiah Degenhardt, Andrea Loehr, Kevin Kwei, Christopher J. Kirk
  • Publication number: 20160177402
    Abstract: Methods of treating a tumor in a subject and methods of determining a treatment regimen for a subject with a tumor are provided herein. In exemplary aspects, the methods comprise measuring the level of expression of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof. In exemplary aspects, the subject is a subject from which a sample was obtained, wherein the level of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof, has been measured from the sample. Related kits, computer readable-storage media, systems, and methods implemented by a processor in a computer are further provided.
    Type: Application
    Filed: August 8, 2014
    Publication date: June 23, 2016
    Inventors: Brian Tuch, Jeremiah Degenhardt, Andrea Loehr, Kevin Kwei, Christopher J. Kirk
  • Publication number: 20150167078
    Abstract: A method is provided for discovering antibodies with desired properties. In one aspect of this invention, oligoclonal single chain repertoires are determined in a target tissue. Single cells from blood are then isolated and sequenced to determine the heavy and light chain pairing in each of thousands of cells. The oligoclonal single chain repertoire is then used to computationally select candidate paired chain antibodies to which the target tissue is antigenic. In another aspect of the invention, oligoclonal heavy and light chain repertoires are determined separately in a target tissue. A list of candidate fully paired antibodies are then identified computationally by an all-by-all pairing of the oligoclonal heavy chain repertoire with the oligoclonal light chain repertoire. This invention has practical application in many biological and medical specialties where antibodies are useful, such as therapeutics, diagnostics, molecular analysis, oncology, transplantation, and infectious disease.
    Type: Application
    Filed: December 12, 2014
    Publication date: June 18, 2015
    Inventors: David Scott Johnson, Andrea Loehr
  • Publication number: 20150154352
    Abstract: Methods and systems are provided for massively parallel genetic analysis of single cells in emulsions or droplets. A biological sample is divided into subsamples of single cells or cell supbopulations, and a fusion complex is formed by molecular linkage and amplification techniques. Methods, apparatuses, and systems are provided for high-throughput, massively parallel analysis of the subsamples. These methods integrate molecular, algorithmic, and engineering approaches. They have broad and useful application in a number of biological and medical fields, including immunology, noninvasive prenatal diagnosis, and noninvasive cancer diagnosis.
    Type: Application
    Filed: June 21, 2013
    Publication date: June 4, 2015
    Applicant: GigaGen, Inc.
    Inventors: David Scott Johnson, Andrea Loehr, Thomas Hunt, Everett Hurteau Meyer, Walter Mathias Howell, Gary Withey
  • Publication number: 20150031555
    Abstract: This invention relates a method to correct for bias inherent to multiplexed sequence amplification. The resulting corrected data is a much more accurate representation of true quantities than unprocessed data.
    Type: Application
    Filed: January 24, 2013
    Publication date: January 29, 2015
    Inventors: David Scott Johnson, Andrea Loehr
  • Publication number: 20140290325
    Abstract: The present invention relates to a stripper (11) for a work roll of a rolling stand, in particular a hot rolling stand, wherein the stripper tip (11) has a stripper tip (5) that makes a contact with the work roll (1), and a first screening element (8) for screening a rolled material (10) from cooling water of the rolling stand, wherein there is provided a second screening element (6) for screening the first screening element (8) from being thermally loaded by the rolled material (10).
    Type: Application
    Filed: September 3, 2012
    Publication date: October 2, 2014
    Applicant: SMS SIEMAG AG
    Inventors: Stephan Fischer, Andreas Loehr
  • Patent number: 8622681
    Abstract: Provided is a specimen carrier supply and delivery device having at least one specimen carrier magazine with separate compartments for receiving interchangeably specimen carriers and a magazine lift, which is adjustable in height in a magazine carrier frame for receiving interchangeably specimen carrier magazines. Two pairs of bars, which stand vertically and parallel to one another, are arranged in the magazine carrier frame, wherein the magazine lift is guided in a height adjustable manner on the two complementary first bars of the bar pairs. An equal-sided coupling frame, which is aligned vertically to the plane formed by the first bars, with a bridge, which is arranged parallel to the plane, is mounted in a sliding manner on the two complementary second bars of the pairs of bars. A linear scale, which is aligned parallel to the direction of the bars, is fastened to the magazine lift.
    Type: Grant
    Filed: April 9, 2013
    Date of Patent: January 7, 2014
    Assignee: Maerzhaeuser Wetzlar GmbH & Co. KG
    Inventors: Christopher Mark Rippl, Uwe Wagner, Lukas Nagel, Ralf Tide, Sebastian Scherer, Andreas Loehr
  • Publication number: 20130264299
    Abstract: Provided is a specimen carrier supply and delivery device having at least one specimen carrier magazine with separate compartments for receiving interchangeably specimen carriers and a magazine lift, which is adjustable in height in a magazine carrier frame for receiving interchangeably specimen carrier magazines. Two pairs of bars, which stand vertically and parallel to one another, are arranged in the magazine carrier frame, wherein the magazine lift is guided in a height adjustable manner on the two complementary first bars of the bar pairs. An equal-sided coupling frame, which is aligned vertically to the plane formed by the first bars, with a bridge, which is arranged parallel to the plane, is mounted in a sliding manner on the two complementary second bars of the pairs of bars. A linear scale, which is aligned parallel to the direction of the bars, is fastened to the magazine lift.
    Type: Application
    Filed: April 9, 2013
    Publication date: October 10, 2013
    Applicant: Maerzhaeuser Wetzlar GmbH & Co. KG
    Inventors: Christopher Mark Rippl, Uwe Wagner, Lukas Nagel, Ralf Tide, Sebastian Scherer, Andreas Loehr