Abstract: A pedal emulator for a vehicle is provided comprising a base part for mounting the pedal emulator to a structure of the vehicle. A pedal lever is pivotable around a rotary axis of the base part. A force generation unit exerts a counterforce on the pedal lever by means of at least one coupling element for mechanically coupling the force generation unit with the pedal lever. The counterforce works counter to an actuating force exerted on the pedal lever. The force generation unit and the coupling element are designed and arranged in such a way that a progression of the counterforce along a pedal travel of the pedal lever (6) takes the form of a non-linear progression in a pedal travel-counterforce diagram.

Abstract: The invention provides a dosing system for an inhalation device, comprising a filling chamber (10); a reservoir chamber (31) which supplies liquid (3) to an aerosol generator (301); and a plunger (20) which includes an overflow chamber (25) and which is pivotable about a hinge (50). The filling chamber has an inner wall (12) which is higher on the side adjacent to the hinge than on the opposite side. When the filling chamber is filled with liquid and the plunger is pivoted into the filling chamber, part of the liquid is displaced over the lower side (17) of the inner wall into the reservoir chamber and some or all of the remaining liquid is displaced into the overflow chamber. The invention also provides an inhalation device comprising the dosing system and a method for dosing liquid to the inhalation device.

Abstract: The present invention relates to certain DPP-4 inhibitors for treating and/or preventing oxidative stress, vascular stress and/or endothelial dysfunction as well as to the use of such DPP-4 inhibitors in treatment and/or prevention of diabetic or non-diabetic patients, including patient groups at risk of cardiovascular and/or renal disease.

Abstract: A mm wave radio communication mesh network comprises a wireless node apparatus comprising a plurality of wireless modems (103) and a configuration controller (307) arranged to perform a node configuration arranged to configure the wireless modems (103) as access point wireless modems or non-access point wireless modems. The configuration controller (307) determines a set of access point wireless modems that have no connection and control them to scan for access point beacons. It then controls a wireless modem that has detected an access point beacon to connect to the access point wireless modem transmitting the beacon. If the connection is successful, the configuration controller (307) proceeds to configure the wireless modem as a non-access point wireless modem and otherwise it is configured as an access point wireless modem.

Abstract: A mm wave radio communication mesh network comprises a wireless node apparatus comprising a plurality of wireless modems (103) and a configuration controller (307) arranged to perform a node configuration arranged to configure the wireless modems (103) as access point wireless modems or non-access point wireless modems. The configuration controller (307) controls a set of wireless modems to scan for access point beacons and determines a first wireless modem that has detected an access point beacon from a first target access point wireless modem. It then configures the first wireless modem as a non-access point wireless modem and controls it to connect to the first target access point modem. If the connection is successful, the configuration controller (307) proceeds to configure another wireless modem as an access point wireless modem.

Abstract: According to some embodiments, a method is performed by a wireless device comprises: receiving a sounding reference signal (SRS) configuration comprising a frequency hopping pattern over a plurality of slots wherein a frequency domain starting position varies per slot; and transmitting SRS according to the received SRS configuration.

Abstract: According to some embodiments, a method performed by a wireless device comprises receiving a sounding reference signal (SRS) configuration for a SRS resource set. The SRS resource set comprises a plurality of SRS resources. The SRS configuration comprises a first periodicity for a first subset of the plurality of SRS resources and a second periodicity for a second subset of the plurality of SRS resources. The method further comprises transmitting the first subset of SRS resources according to the first periodicity and transmitting the second subset of SRS resources according to the second periodicity.

Abstract: The present invention relates to certain DPP-4 inhibitors for treating and/or preventing oxidative stress, vascular stress and/or endothelial dysfunction as well as to the use of such DPP-4 inhibitors in treatment and/or prevention of diabetic or non-diabetic patients, including patient groups at risk of cardiovascular and/or renal disease.

Abstract: A substrate support unit including a turntable which is rotatable around a first axis and which is driven by a first drive. A plurality of substrate carrier units are arranged concentric to the first axis on the turntable. Each of the plurality of substrate carrier units includes a substrate carrier which is rotatable around a corresponding second axis and which is driven by a second drive, wherein all second axes are parallel to the first axis.

Abstract: A gas ring for a PVD-source with a cathode having a target for material deposition. The gas ring includes an inner rim and an outer rim and at least one flange between the inner and the outer rim. The gas ring further includes: —a gas inlet; —gas openings arranged circumferentially in or near the inner rim; —at least one circumferential gas channel connected to the gas inlet and/or the gas openings; —a cooling duct.

Abstract: The invention provides a dosing system for an inhalation device, comprising a filling chamber (10); a reservoir chamber (31) which supplies liquid (3) to an aerosol generator (301); and a plunger (20) which includes an overflow chamber (25) and which is pivotable about a hinge (50). The filling chamber has an inner wall (12) which is higher on the side adjacent to the hinge than on the opposite side. When the filling chamber is filled with liquid and the plunger is pivoted into the filling chamber, part of the liquid is displaced over the lower side (17) of the inner wall into the reservoir chamber and some or all of the remaining liquid is displaced into the overflow chamber. The invention also provides an inhalation device comprising the dosing system and a method for dosing liquid to the inhalation device.

Abstract: A blister piercing element for puncturing the lid of a blister containing a dose of medicament for inhalation by a user. The piercing element has an outlet opening for the passage of medicament entrained in an airflow out of the blister and, a piercing head extending beyond and overhanging the opening that cuts a flap in a lid of a blister and pushes it away from the opening during insertion.

Abstract: An inhaler comprising a housing defining a chamber to receive a strip having a plurality of blisters each containing a dose of medicament for inhalation by a user is disclosed. It comprises an actuating lever and a blister strip drive member rotatably mounted in the chamber to sequentially move each blister into a blister opening position. The blister strip drive member and the actuating lever comprise a drive gear and a drive gear element, respectively, that cooperate to effect rotation of the blister strip drive member in response to rotation of the actuating lever. The drive gear and drive gear element are disposed on the outside of the housing remote from the chamber.

Abstract: An inhaler is disclosed. It comprises a housing to receive a strip having a surface and a plurality of blister pockets depending from said surface. Each blister pocket contains a dose of medicament for inhalation by a user. The inhaler has a blister strip drive mechanism including a blister strip drive member shaped to contact the strip along a line defined by the crease between a blister pocket and said surface, to drive said strip.

Abstract: An inhaler comprising a housing to receive a strip having a plurality of blisters is disclosed. Each blister has a puncturable lid and contains a dose of medicament for inhalation by a user. A mouthpiece is pivotally mounted to the housing through which a dose of medicament is inhaled by a user. The inhaler also has an actuating mechanism including a lever operable to sequentially move each blister into alignment with a blister piercing member depending from the mouthpiece. The actuating lever is also operable to cause the mouthpiece to pivot so that the blister piercing member punctures the lid of an aligned blister so that, when a user inhales through the mouthpiece, an airflow through the blister is generated to entrain the dose contained therein and carry it, via the mouthpiece, into the user's airway.

Abstract: An inhaler comprising a housing to receive a strip having a plurality of blisters is disclosed. Each blister has a puncturable lid and contains a dose of medicament for inhalation by a user. A mouthpiece is pivotally mounted to the housing through which a dose of medicament is inhaled by a user. The inhaler also has an actuating mechanism including a lever operable to sequentially move each blister into alignment with a blister piercing member depending from the mouthpiece. The actuating lever is also operable to cause the mouthpiece to pivot so that the blister piercing member punctures the lid of an aligned blister so that, when a user inhales through the mouthpiece, an airflow through the blister is generated to entrain the dose contained therein and carry it, via the mouthpiece, into the user's airway.

Abstract: A closing unit for a vacuum valve includes a first valve plate (7) for closing a first valve opening (2) of the vacuum valve, a second valve plate (8) for closing a second valve opening (3) of the vacuum valve, and a carrier plate (19) that lies between the valve plates (7, 8) to which the valve plates (7, 8) are fastened detachably. For fastening a corresponding valve plate (7, 8) to the carrier plate (19), at least one clamping piece (20, 21) is used by which interacting clamping surfaces (22-26) are clamped with each other. Of the interacting clamping surfaces (22-26), at least one is constructed as an angular surface by which the corresponding valve plate (7, 8) is pressed against the carrier plate (19).