Patents by Inventor Andreas MATOUSCHEK

Andreas MATOUSCHEK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeting proteins for degradation
    Patent number: 11008372
    Abstract: Embodiments provided here include recombinant polypeptides, termed degradons, comprising a target binding domain and a proteasome-binding domain. Degradons of the embodiments are able to selectively target and degrade proteins bound by the target-binding domain, such as proteins associated with disease. Vectors encoding degradons and methods of treating disease with degradons and degradon expression vectors are likewise provided.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: May 18, 2021
    Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, NORTHWESTERN UNIVERSITY
    Inventor: Andreas Matouschek
  • TARGETING PROTEINS FOR DEGRADATION
    Publication number: 20180327462
    Abstract: Embodiments provided here include recombinant polypeptides, termed degradons, comprising a target binding domain and a proteasome-binding domain. Degradons of the embodiments are able to selectively target and degrade proteins bound by the target-binding domain, such as proteins associated with disease. Vectors encoding degradons and methods of treating disease with degradons and degradon expression vectors are likewise provided.
    Type: Application
    Filed: November 7, 2016
    Publication date: November 15, 2018
    Inventor: Andreas MATOUSCHEK