Abstract: An anti-cancer agent for use in a method for the treatment of cancer, in particular gynecological cancer, in a patient, wherein the method comprises subjecting said patient to a plurality of therapy cycles, in particular chemotherapy cycles, with the anti-cancer agent, which can be a chemotherapeutic agent, and subjecting said patient to a fasting mimicking diet (FMD) for a period of 30-42 hours before each therapy cycle and 18-30 hours after each therapy cycle.