Abstract: The invention concerns a microscopy method and a microscopy apparatus (100), with an illumination modulator (17) which is configured so as to produce a plurality of points of illumination (8, 11) during a scan of a light strip (3) of the illuminating light (27a) with an illumination modulator (17a), the points being in the form of an asymmetrical 2D Bravais lattice (G4, G5, G6) with a first, longer primitive vector (a) and a second, shorter primitive vector (b) and wherein the projection of the first primitive vector (a) onto the axial direction (3a) of the light strip (3) is longer than the projection of the second primitive vector (b) onto the axial direction (3a) of the light strip (3). In combination with a ROI of a detector synchronised to the illumination line, a more rapid confocal acquisition method is obtained with a better signal-to-noise ratio.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: A switch cabinet arrangement having at least one housing and at least one electrochemical energy storage accommodated therein and an extinguishing system, wherein at least one gas-permeable membrane is arranged in each case on at least two outer walls of the at least one housing, diametrically opposite one another, via which a gas atmosphere in the interior of the at least one housing is fluidically connected to a gas atmosphere in the surroundings of the at least one housing.

Abstract: A dental coil comprises a first element and a second element. The first element is composed of a dimensionally stable material and has a recess that is configured to receive at least one of a mouth region or a nose region of a patient when the dental coil is positioned on the jaw region of the patient during use. The second element has a flexible element that is configured to allow the flexible element to take the shape of the jaw region of the patient. The first element and the second element have an antenna configured to receive high-frequency signals in a frequency and power range of a magnetic resonance measurement.

Abstract: A device for adjusting a printing head includes a step-by-step switching mechanism, an actuator for shifting the step-by-step switching mechanism, and a locking disk supported for rotation. A first shifting tongue is provided for incrementally rotating the locking disk in a first direction of rotation. The first shifting tongue has two elongated holes for guidance purposes, one of which has a lateral recess. It is thus possible to adjust printing heads with a high degree of accuracy while saving time and costs. The device is preferably implemented in industrial inkjet printing.

Abstract: A system to be used for transmitting ultrasonic vibration, the system including a sonotrode designed to vibrate in a stationary wave having at least one node position between the distal end and the proximal end of the sonotrode, and a guide shaft with a through opening. During operation the sonotrode extends through the through opening of the guide shaft and the distal end of the guide shaft is situated on a distal side of the most distal node position of the sonotrode. The sonotrode and the guide shaft are adapted to each other for radial clearance between the sonotrode and the guide shaft to be a minimum for a sonotrode portion comprising the most distal node position.

Abstract: A process for producing at least one pyrogenic compound can be performed. A burner suitable for use in said process has at least four concentric tubes, where a second tube is arranged around the central tube. A process for making the burner can be performed, and a production facility that has at least one burner can be made.

Abstract: An optical component serves as a nonlinear photodetector for generating a nonlinear electrical signal. The component comprises a first electrically conductive layer, a second electrically conductive layer and an absorption layer. The absorption layer is arranged between the first and the second electrically conductive layer and has a layer thickness of at least 500 nm. The electrical signal is generated by the component by applying a voltage at the component and irradiating the component with electromagnetic radiation in a first wavelength range (?1) with a radiation intensity of less than 10 nW/mm2 and also irradiating the optical component with electromagnetic radiation in a second wavelength range (?2) that is different from the first wavelength range (?1) and a radiation intensity of less than 100 nW/mm2.

Abstract: A method for joining two metallic, tubular joining members to one another, the method including arranging two metallic, tubular joining members with respect to one another in an overlapping or end-face manner, and joining the joining members by material bond along a joining zone of the joining members. In the joining, a chain of joining spots extending in the circumferential direction of the joining members is produced in the joining zone, wherein successive joining spots in the chain overlap, wherein, in the joining, the joining spots are produced by means of TIG pulse welding with an arc time of up to 100 ms, preferably of up to 50 ms, wherein an arc of a welding pulse of the TIG pulse welding is extinguished after the arc time has been reached. A corresponding welding apparatus is also described.

Abstract: A medical device of an embodiment includes at least one movably mounted and motor-adjustable component; at least one drive unit for adjusting the at least one component; at least one motor control unit associated with the drive unit; and at least one sensing unit for sensing a position parameter dependent on the position of the at least one component. According to an embodiment of the invention, a safety function is integrated in the motor control unit. The safety function limits at least one operating parameter associated with the motion of the at least one component to be performed. An apparatus control unit controls the drive unit in dependence on the position parameter in accordance with the safety function. At least one embodiment of the invention further relates to a method for operating a medical device.

Abstract: The present invention relates to the compounds of formula (I) wherein the variables are defined as given in the description and claims. The invention further relates to their use and composition.

Abstract: A method for adjusting a bolus amount of insulin for a meal event using a control unit having a processing unit and a touch screen display as well as a medical control device and a medical system configured to perform the method. Additionally, the present disclosure relates to a computer program or computer program product that, when executed, performs the method. A carbohydrate-based bolus amount of insulin can be delivered in a first bolus and a second bolus. A movable slider displayed on the touch screen display can be used to adjust the relative amounts of the first and second boli.

Abstract: A peptide consists of the amino acid sequence GLIHLEGDTV (SEQ ID NO: 53) in the form of a pharmaceutically acceptable salt, in which the peptide has the ability to bind to an MHC class-I molecule and, when bound to MHC, is capable of being recognized by CD8 T cells. A composition contains a peptide consisting of the amino acid sequence GLIHLEGDTV (SEQ ID NO: 53), an adjuvant, and a pharmaceutically acceptable carrier.

Abstract: A semantic texture map system to generate a semantic texture map based on a 3D model that comprises a plurality of vertices that include coordinate that indicate positions of the plurality of vertices, a UV map, and a semantic segmentation image that comprises a set of semantic labels.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: A printing unit of an inkjet printing machine includes a printing bar with printing heads disposed in a row for printing on a printing substrate, a cleaning device for cleaning the printing heads, a device for individually adjusting the printing heads, at least one respective step-by-step switching mechanism assigned to every printing head, and a common actuator for shifting the step-by-step switching mechanisms of different printing heads. The actuator is movable into positions opposite every step-by-step switching mechanism. The cleaning device is movable and the actuator is disposed on the cleaning device for joint movement so that the actuator can be positioned opposite every step-by-step switching mechanism. It is thus possible to adjust printing heads with great precision while saving time and costs, which is preferably implemented in industrial inkjet printing.

Abstract: A device for measuring a measured variable of a medium includes: a measuring cell, through which the medium can flow, in the inner chamber of which a channel opens on an inlet side and on an outlet side; a first duct opening into the inner chamber; a first component in the first duct such that an end portion of the first component projects into the inner chamber; and a first molded part, which surrounds on the end portion of the first component and a hollow chamber adjacent to the first component in the inner chamber, and includes, for each channel, a recess which connects the hollow chamber to the corresponding channel and is configured as a cross-sectional converter.

Abstract: A device for adjusting a printing head includes a step-by-step switching mechanism, an actuator for shifting the step-by-step switching mechanism, and a locking disk supported for rotation. A first shifting tongue is provided for incrementally rotating the locking disk in a first direction of rotation. The first shifting tongue has two elongated holes for guidance purposes, one of which has a lateral recess. It is thus possible to adjust printing heads with a high degree of accuracy while saving time and costs. The device is preferably implemented in industrial inkjet printing.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: Methods, systems, and devices for generating a persistent world-space ground (or floor) segmentation map (or “texture”) for use in augmented or virtual reality 3D experiences.