Patents by Inventor Andreas Muller-Hermann

Andreas Muller-Hermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210024978
    Abstract: It is disclosed a method for the detection of an amplification of nucleic acids in which substantially use is made of the fact that a pre-defined nucleic acid chain (target sequence) can be multiplied/amplified in the presence of a target sequence-specific activator oligonucleotide. The target sequence-specific activator oligonucleotide causes the separation of re-synthesized complementary primer extension products by means of strand displacement, so that a new primer oligonucleotide can attach to the respective template strand. The thus formed complex of a primer oligonucleotide and a template strand can initiate a new primer extension reaction. The thus formed primer extension products in turn function as templates, so that an exponential amplification reaction results. Amplification is detected by a detection system.
    Type: Application
    Filed: February 25, 2019
    Publication date: January 28, 2021
    Applicant: AGCT GmbH
    Inventors: Christian GRUNWALD, Dmitry CHERKASOV, Norbert BASLER, Claus BECKER, Hans-Joerg HESS, Andreas MÜLLER-HERMANN
  • Patent number: 9994894
    Abstract: The invention relates to a novel method for the enzymatic marking of nucleic acid chains (target sequences) by means of nucleotide conjugates. Said nucleotide conjugates are able, under reaction conditions, to specifically bind to the target sequence and integrate into the complementary growing strand by means of a polymerase. The nucleic acid chains marked by such conjugates can be bound to the solid phase. The marking can be carried out parallel to the enzymatic amplification of target sequences.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: June 12, 2018
    Assignee: AGCT GMBH
    Inventors: Dmitry Cherkasov, Claus Becker, Norbert Basler, Andreas Muller-Hermann, Petra Van Husen
  • Publication number: 20150086981
    Abstract: The invention relates to a novel method for the enzymatic marking of nucleic acid chains (target sequences) with nucleotide conjugates. Under reaction conditions, said nucleotide conjugates are able to bind to a target sequence, and can be incorporated into the complementary growing strand by way of a polymerase. The nucleotide conjugates can be used for sequencing nucleic acid chains.
    Type: Application
    Filed: May 4, 2012
    Publication date: March 26, 2015
    Applicant: GENOVOXX GMBH
    Inventors: Dmitry Cherkasov, Claus Becker, Norbert Basler, Andreas Müller-Hermann, Petra Van Husen
  • Publication number: 20140295438
    Abstract: The invention relates to a novel method for the enzymatic marking of nucleic acid chains (target sequences) by means of nucleotide conjugates. Said nucleotide conjugates are able, under reaction conditions, to specifically bind to the target sequence and integrate into the complementary growing strand by means of a polymerase. The nucleic acid chains marked by such conjugates can be bound to the solid phase. The marking can be carried out parallel to the enzymatic amplification of target sequences.
    Type: Application
    Filed: April 26, 2012
    Publication date: October 2, 2014
    Applicant: GENOVOXX GMBH
    Inventors: Dmitry Cherkasov, Claus Becker, Norbert Basler, Andreas Muller-Hermann, Petra Van Husen