Patents by Inventor Andreas Pickl
Andreas Pickl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11911741Abstract: The present invention relates to a diatomaceous earth composition with a low endotoxin content, comprising an agglomerated mixture of calcined diatomaceous earth particles and water, wherein the mass ratio of calcined diatomaceous earth particles and water is in the range of 1:1.0 to 1:2.0, and wherein the endotoxin content of the diatomaceous earth composition is equal to or less than 0.5 EU/mL. In a further aspect, the present invention relates to a method for producing the diatomaceous earth composition with a low endotoxin content. In another aspect, the present invention relates to the use of the diatomaceous earth composition with a low endotoxin content as a precoat agent for the precoat filtration in biopharmaceutical applications.Type: GrantFiled: October 9, 2018Date of Patent: February 27, 2024Assignee: Sartorius Stedim Biotech GMBHInventors: Karl Pflanz, Florian Hebenstreit, Andreas Pickl
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Patent number: 11826720Abstract: The present invention relates to an improved diatomaceous earth composition containing salt water. The diatomaceous earth composition according to the present invention comprises an agglomerated mixture of calcined diatomaceous earth particles, water and at least one inorganic salt, wherein the mass ratio of the calcined diatomaceous earth particles and water is in the range of 1:1.0 to 1:2.0, and wherein the content of the at least one inorganic salt is equal to or more than 0.25 parts by mass based on 100 parts by mass of water. In a further aspect, the present invention relates to a method for producing the diatomaceous earth composition according to the present invention. In another aspect, the present invention relates to the use of the diatomaceous earth composition according to the present invention as an agent for precoat filtration or dynamic body feed filtration in biopharmaceutical applications.Type: GrantFiled: November 6, 2020Date of Patent: November 28, 2023Assignee: Sartorius Stedim Biotech GmbHInventors: Karl Pflanz, Andreas Pickl, Florian Hebenstreit
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Publication number: 20230311035Abstract: A filtering system (10) includes a filtering apparatus having a filter unit for receiving liquid to be filtered, a receptacle for receiving filtered liquid, and an adapter (14) for coupling the filter unit to the receptacle, and also includes a base (12) having a cradle (26) for receiving the filtering apparatus and a base vacuum delivery port (28). The adapter includes an adapter vacuum receiving port (22) coupled to the vacuum delivery port for driving the liquid through the filter and—as filtered liquid—into the receptacle. The cradle and the adapter have an interlocking mechanism (52, 54) that locks the filtering apparatus to the cradle in a locking position in which the vacuum receiving port is sealingly coupled to the base vacuum delivery port. The base vacuum delivery port has a vacuum valve (30) constituted as a normally-closed valve automatically forced open when the filtering apparatus locks to the cradle.Type: ApplicationFiled: June 6, 2023Publication date: October 5, 2023Inventors: Karl PFLANZ, Sebastian PRUEHL, Andreas PICKL, Roland LEETSCH, Adam GILBERT, Martin PURSHOUSE
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Patent number: 11666840Abstract: A filtering system (10) includes a filtering apparatus having a filter unit for receiving liquid to be filtered, a receptacle for receiving filtered liquid, and an adapter (14) for coupling the filter unit to the receptacle, and also includes a base (12) having a cradle (26) for receiving the filtering apparatus and a base vacuum delivery port (28). The adapter includes an adapter vacuum receiving port (22) coupled to the vacuum delivery port for driving the liquid through the filter and—as filtered liquid—into the receptacle. The cradle and the adapter have an interlocking mechanism (52, 54) that locks the filtering apparatus to the cradle in a locking position in which the vacuum receiving port is sealingly coupled to the base vacuum delivery port. The base vacuum delivery port has a vacuum valve (30) constituted as a normally-closed valve automatically forced open when the filtering apparatus locks to the cradle.Type: GrantFiled: January 8, 2021Date of Patent: June 6, 2023Assignee: SARTORIUS STEDIM BIOTECH GMBHInventors: Karl Pflanz, Sebastian Pruehl, Andreas Pickl, Roland Leetsch, Adam Gilbert, Martin Purshouse
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Publication number: 20220395807Abstract: The present invention relates to an improved diatomaceous earth composition containing salt water. The diatomaceous earth composition according to the present invention comprises an agglomerated mixture of calcined diatomaceous earth particles, water and at least one inorganic salt, wherein the mass ratio of the calcined diatomaceous earth particles and water is in the range of 1:1.0 to 1:2.0, and wherein the content of the at least one inorganic salt is equal to or more than 0.25 parts by mass based on 100 parts by mass of water. In a further aspect, the present invention relates to a method for producing the diatomaceous earth composition according to the present invention. In another aspect, the present invention relates to the use of the diatomaceous earth composition according to the present invention as an agent for precoat filtration or dynamic body feed filtration in biopharmaceutical applications.Type: ApplicationFiled: November 6, 2020Publication date: December 15, 2022Inventors: Karl PFLANZ, Andreas PICKL, Florian HEBENSTREIT
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Publication number: 20210129057Abstract: A filtering system (10) includes a filtering apparatus having a filter unit for receiving liquid to be filtered, a receptacle for receiving filtered liquid, and an adapter (14) for coupling the filter unit to the receptacle, and also includes a base (12) having a cradle (26) for receiving the filtering apparatus and a base vacuum delivery port (28). The adapter includes an adapter vacuum receiving port (22) coupled to the vacuum delivery port for driving the liquid through the filter and—as filtered liquid—into the receptacle. The cradle and the adapter have an interlocking mechanism (52, 54) that locks the filtering apparatus to the cradle in a locking position in which the vacuum receiving port is sealingly coupled to the base vacuum delivery port. The base vacuum delivery port has a vacuum valve (30) constituted as a normally-closed valve automatically forced open when the filtering apparatus locks to the cradle.Type: ApplicationFiled: January 8, 2021Publication date: May 6, 2021Inventors: Karl PFLANZ, Sebastian PRUEHL, Andreas PICKL, Roland LEETSCH, Adam GILBERT, Martin PURSHOUSE
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Publication number: 20200261883Abstract: The present invention relates to a diatomaceous earth composition with a low endotoxin content, comprising an agglomerated mixture of calcined diatomaceous earth particles and water, wherein the mass ratio of calcined diatomaceous earth particles and water is in the range of 1:1.0 to 1:2.0, and wherein the endotoxin content of the diatomaceous earth composition is equal to or less than 0.5 EU/mL. In a further aspect, the present invention relates to a method for producing the diatomaceous earth composition with a low endotoxin content. In another aspect, the present invention relates to the use of the diatomaceous earth composition with a low endotoxin content as a precoat agent for the precoat filtration in biopharmaceutical applications.Type: ApplicationFiled: October 9, 2018Publication date: August 20, 2020Inventors: Karl Pflanz, Florian Hebenstreit, Andreas Pickl
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Publication number: 20190054397Abstract: A device for purifying protein from a protein-containing fluid includes a prefilter unit, which has at least one size exclusion filter, a membrane adsorber unit, which has at least one porous membrane with functional constituents which adsorb the protein to be purified, and a collecting container. The collecting container, the membrane adsorber unit and the prefilter unit are configured such that the collecting container is suitable for receiving the membrane adsorber unit; and the membrane adsorber unit is suitable for receiving the prefilter unit. An associated method for purifying protein from a protein-containing fluid using the device is also disclosed.Type: ApplicationFiled: August 14, 2018Publication date: February 21, 2019Inventors: Karl Pflanz, Andreas Pickl, Holger Linne, Vanessa Ransiek, Kathrin Schroeder-Tittmann