Abstract: Silanes of the formula: [(ZmRnSi—R1o—)pR2q—Y—C(X)—Y—]rG[—Y—(X)C—Y—R3]s??(I), in which m+n=3; m=1, 2 or 3; n=0, 1 or 2; o=0 or 1, and q=1 if o=0; p=1, 2, 3 or 4; q=0 or 1, and p=1 if q=0; r, s=1, 2 or 3; and Z is a hydrolyzable atom or group; R is a nonhydrolyzable group without an epoxide group; R1 is a divalent group; R2 is a (p+1)-valent group; R3 is a nonhydrolyzable, epoxy-containing group; X is an oxygen atom and/or sulfur atom; G is an (r+s)-valent cyclic group; Y is an oxygen atom, sulfur atom or imino group >NR4 where R4=hydrogen atom, group R, group (ZmRnSi—R1o—)pR2q—, group R3—, group (ZmRnSi—R1o—)pR2q—NH—C(X)— or group R3—NH—C(X)—; processes for their preparation, and their use.

Abstract: The use of curable mixtures comprising (A) at least one phosphonic diester and/or at least one diphosphonic diester and (B) at least one compound containing at least two condensable silane groups, as coupling agents, particularly as coupling agents in laminates comprising at least one substrate, at least one coating, at least one adhesive layer, and at least one sheet, and also a new process for producing such laminates using the coupling agents, the laminates which are producible using the coupling agents, and thermally curable mixtures comprising the coupling agents and at least one thermally curable polyester (C).

Abstract: The invention concerns antibodies and antibody fragments, specifically recognising the EphB4 receptor comprising heavy chains and light chain, comprising light and heavy CDR's, and their use as medicament for the treatment of pathological angiogenesis, in particular cancer therapy.

Abstract: Autocatalyzed, thermally curable compositions free from external catalysts and comprising condensates of silanes which contain at least one of hydrolyzable atoms and hydrolyzable groups and processes for preparing them, and their use for producing thermally cured compositions.

Abstract: An aqueous dispersion with a pH of from 2 to 7, comprising (A) at least one swellable polymer or oligomer containing anionic and/or potentially anionic functional groups, (B) surface-modified, cationically stabilized, inorganic nanoparticles of at least one kind, and (C) at least one amphiphile; and its use for producing highly scratch-resistant coatings, moldings, and self-supporting films.

Abstract: For readjusting a polarization drift in the transmission of a polarization-encoded optical signal from a transmitter via a light guide to a receiver, optical auxiliary signals having the same wavelength as the polarization-encoded signal as well as different polarizations as in correspondence with a first base and a second base are fed into the light guide on the side of the transmitter while the transmission of the polarization-encoded signal is interrupted, and the optical auxiliary signals are picked up from the light guide and checked for shifts of the different polarizations by a polariometer on the side of the receiver, whereupon, in the event of the detection of polarization shifts, the different polarizations shifted during the transmission are displaced in the sense of the polarization set values via a polarization controller associated with the light guide.

Abstract: Liquid, thermally curable mixtures comprising, (A) low molecular weight polyols having at least three hydroxyl groups and a hydroxyl group content corresponding to a theoretical OH number of 800 to 1900 mg KOH/g, (B) compounds selected from the group consisting of cyclic and acyclic C9-C16 alkanes functionalized with hydroxyl groups or hydroxyl and at least one thiol group, and (C) low molecular weight or oligomeric compounds having reactive functional groups (c1) complementary to hydroxyl groups and thiol groups, processes for preparing them, and their use.

Abstract: Disclosed herein is a thermally curable mixture, comprising at least one phosphonic diester (A), at least one diphosphonic diester (A), or at least one phosphonic diester and at least one diphosphonic diester (A); and at least one compound (B) which can be reacted by transesterification, transamidation, self-condensation of N-hydroxyalkylamino groups, self-condensation of N-alkoxyalkylamino groups, transacctalization of N-alkoxyalkylamino groups, acctalization of N-hydroxyalkylamino groups, or a combination thereof. Also disclosed is a process for making the thermally curable mixture, and a cured material comprising the product of thermally curing the mixture.

Abstract: Disclosed herein is a silane-functional mixture, comprising at least one phosphonic diester (A), at least one diphosphonic diester (A), or at least one phosphonic diester and one diphosphonic diester (A), and at least one compound (B) comprising at least two condensable silane groups.

Abstract: The invention relates to a coating material comprising (A) at least 50% by weight, based on the amount of nonvolatile substances in the coating material, of at least one compound (A1) containing at least one reactive group of the formula(I) —NR—C(O)—N—(X—SiR?x(OR?)3-x)n(X?—SiR?y(OR?)3-y)m ??(I) where R=hydrogen, alkyl, cycloalkyl, aryl or aralkyl, the carbon chain being uninterrupted or interrupted by nonadjacent oxygen, sulfur or NRa groups, with Ra=alkyl, cycloalkyl, aryl or aralkyl, R?=hydrogen, alkyl or cycloalkyl, the carbon chain being uninterrupted or interrupted by nonadjacent oxygen, sulfur or NRa groups, X, X?=linear and/or branched alkylene or cycloalkylene radical of 2 to 20 carbon atoms, R?=alkyl, cycloalkyl, aryl or aralkyl, the carbon chain being uninterrupted or interrupted by nonadjacent oxygen, sulfur or NRa groups, n=0 to 2, m=0 to 2, m+n=2, and x, y=0 to 2, (B) a catalyst for the crosslinking of the —Si(OR?)3-X(y) units, and (C) an aprotic solvent or a mixture of aprotic solvents.

Abstract: Transparent coatings with a thickness of at least 30 ?m, a relative elastic resilience to DIN 55676 of at least 70%, and a scratch resistance corresponding to a score of not more than 2 in the steel wool scratch test to DIN 1041 after 10 double strokes; process for producing them, and their use.

Abstract: The present invention inter alia relates to methods for the prevention, amelioration or treatment of medical conditions associated with an alteration in normal goblet cell function. It also relates to methods of screening for disease-relevant markers indicative of an increased risk of a subject of developing such a condition. It furthermore relates to an animal model useful for studying said conditions and the molecular mechanisms underlying them, and uses of that animal model, for example for the identification of diagnostic markers or agents useful for the prevention, amelioration, or treatment of a goblet cell-related disorder. Novel agents useful in the above methods, and novel pharmaceutical compositions are likewise provided. The invention further relates to screening methods for agonists and antagonists useful for performing said methods.

Abstract: A coating material comprising (A) at least 50% by weight, based on the amount of nonvolatile substances in the coating material, of at least one compound (A1) and/or (A1?) containing at least two reactive groups of the formula I —X—SiR?x(OR?)3-x??(I) where R?=hydrogen, alkyl or cycloalkyl, the carbon chain being uninterrupted or interrupted by nonadjacent oxygen, sulfur or NRa groups, where Ra alkyl, cycloalkyl, aryl or aralkyl, X=linear and/or branched alkylene or cycloalkylene radical having 2 to 20 carbon atoms, R?=alkyl, cycloalkyl, aryl or aralkyl, the carbon chain being uninterrupted or interrupted by nonadjacent oxygen, sulfur or NRa groups, and x=0 to 2, (B) a catalyst for the crosslinking of the —Si(OR?)3-x units, and (C) an organic solvent or a mixture of organic solvents, the reactive groups (I) being crosslinked, in the course of curing of the coating material, such that nanoindentation testing on the cured coat results in the following properties: a. elastic volume recovery >86.5%, b.

Abstract: A thermosetting coating material comprising (A) at least 50% by weight, based on the amount of nonvolatile substances in the coating material of (A1) from 0% to 50% by weight, based on the entirety of components (A1) and (A2), of a polymethacrylate copolymer containing more than 50% by weight, based on the entirety of comonomers in the copolymer (A1), of free-radically polymerizable, ethylenically unsaturated compounds (a1) containing at least one reactive group of the formula I —X—SiR?x(OR?)3-x ??(I) and (A2) from 50% to 100% by weight, based on the entirety of components (A1) and (A2), of an adduct of polyisocyanate and alkoxysilane, (A2) containing at least one reactive group of the formula II: —NR—C(O)—N—(X—SiR?x(OR?)3-x)n(X?—SiR?y(OR?)3-y)m ??(II) (B) a catalyst for the crosslinking of the —Si(OR?)3-x units, and (C) an aprotic solvent or a mixture of aprotic solvents.

Abstract: The invention relates to a short-pulse laser device (11) with a preferably passive mode coupling. Said device comprises a resonator (12) which contains a laser crystal (14) in addition to several mirrors (M1-M7, OC) that define a long resonator arm (17) and a short resonator arm (16), one (M1) of said mirrors forming a pump beam coupling-in mirror and another (OC) forming a laser beam output coupler and comprising a multiple reflection telescope (18) that increases the length of the resonator and is allocated to the resonator arms (16, 17). Said telescope is constructed using mirrors (25, 26), in order to reflect a laser beam (15) that is coupled into the space between them back and forth several times, prior to being decoupled back into the other resonator, whereby sequential eccentric reflection points (1 to 8; 1? to 8?) on the mirrors (25, 26) are offset in relation to one another.

Abstract: Modified open-cell foams having a density in the range from 5 to 1000 kg/m3, a mean pore diameter in the range from 1 ?m to 1 mm, a BET surface area in the range from 0.1 to 50 m2/g and an acoustic absorption factor of more than 50% at a frequency of 2000 Hz at a layer thickness of 50 mm, comprising in the range from 1 to 4000 ppm, based on the weight of the unmodified open-cell foam, fixed particles (b) having a mean diameter (number average) in the range from 5 nm to 900 nm.

Abstract: Pseudoplastic aqueous dispersions comprising particles which are solid and/or of high viscosity, are dimensionally stable under storage and application conditions, are in dispersion in a continuous aqueous phase and said particles comprise surface-modified nanoparticles whose surface is covered fully or almost fully by modifying groups, processes for preparing them, and their use

Abstract: The present invention relates to novel (meth)acrylic esters of polyalkoxylated trimethylolpropane of the formula where EO is O—CH2-CH2- PO is independently at each instance O—CH2-CH(CH3)- or O—CH(CH3)-CH2- n1, n2 and n3 are independently 4, 5 or 6, n1+n2+n3 is 14, 15 or 16, m1, m2 and m3 are independently 1, 2 or 3, m1+m2+m3 is 4, 5 or 6, R1, R2 and R3 are independently H or CH3, a simplified process for preparing these esters and the use of reaction mixtures thus obtainable.

Abstract: Autocatalyzed, thermally curable compositions free from external catalysts and comprising condensates of silanes which contain at least one of hydrolyzable atoms and hydrolyzable groups and processes for preparing them, and their use for producing thermally cured compositions.

Abstract: Curable compositions comprising deagglomerated barium sulfate containing at least one dispersant and at least one crystallization inhibitor and having a primary particle size <0.5 ?m, preferably <0.1 ?m, in particular <30 nm, and their use.