Patents by Inventor Andreas R. Klatt

Andreas R. Klatt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of autoantibodies for diagnosing degenerative diseases of the skeletal system
    Patent number: 11609231
    Abstract: Methods, kits, and active ingredients for diagnosing or treating arthritis or a degenerative disease of the skeletal system, or for selection of subjects for therapy. The methods for diagnosing arthritis involve the detection of an autoantibody, which is associated with arthritis, or excluding the presence of an autoantibody against collagen II. The methods for diagnosing a degenerative disease of the skeletal system, involve the detection of an autoantibody against thrombospondin-4 or COMP. The kits contain a detection agent for an autoantibody and can be used for diagnosing arthritis or a degenerative disease of the skeletal system. The active ingredient can be used for treating or preventing autoimmune-associated arthritis.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: March 21, 2023
    Assignee: UNIVERSITÄT ZU KÖLN
    Inventors: Andreas R. Klatt, Johannes Ruthard, Benedikt Ostendorf, Matthias Schneider, Georg Pongratz, Gabriele Hermes
  • Detection of Autoantibodies for Diagnosing Degenerative Diseases of the Skeletal System
    Publication number: 20210109097
    Abstract: The invention relates to a method for diagnosing arthritis, comprising the detection of an autoantibody, which is associated with arthritis, to a method for diagnosing a degenerative disease of the skeletal system, comprising the detection of an autoantibody against thrombospondin-4 or COMP, to a method for diagnosing arthritis, comprising excluding the presence of an autoantibody against collagen II, to a kit for diagnosing arthritis or a degenerative disease of the skeletal system, comprising a detection agent for an autoantibody, to the use of the kit for diagnosing arthritis or a degenerative disease of the skeletal system, to an active ingredient for use for treatment or preventing autoimmune-associated arthritis and to the diagnostic method for selection of subjects for therapy.
    Type: Application
    Filed: December 12, 2018
    Publication date: April 15, 2021
    Applicant: UNIVERSITÄT ZU KÖLN
    Inventors: Andreas R. Klatt, Johannes Ruthard, Benedikt Ostendorf, Matthias Schneider, Georg Pongratz, Gabriele Hermes
  • Use of PAK inhibitor for the treatment of a joint disease
    Patent number: 8187828
    Abstract: The invention refers to the use of a p21-activated kinase (PAK) inhibitor as a target protein for the discovery of a PAK inhibitor as a medicament for the treatment of a joint disease.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: May 29, 2012
    Assignee: Sanofi-Aventis Deutschland GmnH
    Inventors: Sebastian Barradeau, Eckart Bartnik, Joerg Czech, Andreas R. Klatt, Ekkehard Leberer, Thomas Leeuw
  • USE OF PAK INHIBITOR FOR THE TREATMENT OF A JOINT DISEASE
    Publication number: 20090104279
    Abstract: The invention refers to the use of a p21-activated kinase (PAK) inhibitor as a target protein for the discovery of a PAK inhibitor as a medicament for the treatment of a joint disease.
    Type: Application
    Filed: March 26, 2008
    Publication date: April 23, 2009
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Sebastian BARRADEAU, Eckart BARTNIK, Joerg CZECH, Andreas R. Klatt, Ekkehard LEBERER, Thomas LEEUW
  • Use of PAK inhibitor for the treatment of a joint disease
    Patent number: 7364887
    Abstract: The invention refers to the use of a p21-activated kinase (PAK) inhibitor for the treatment of a joint disease such as osteoarthritis or rheumatoid arthritis or for the treatment of a joint pain and the use of PAK as a target protein for the discovery of a PAK inhibitor as a medicament for the treatment of a joint disease.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: April 29, 2008
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Sebastian Barradeau, Eckart Bartnik, Joerg Czech, Andreas R. Klatt, Ekkehard Leberer, Thomas Leeuw