Abstract: A surgical microscope includes an image capture unit having an image sensor, a detection beam path, an image evaluation unit, a connection region for attaching a protective glass module with an objective protective glass. The image sensor has a detection region which has a used detection region for capturing the object region, and a partial detection region, which is not assigned to the used detection region. The image capture unit is configured such that, when the protective glass module with the objective protective glass is arranged at the connection region, a detail of the protective glass module with the objective protective glass is capturable by the partial detection region of the image sensor. The image evaluation unit is configured to generate a signal when an objective protective glass is detectable by the evaluation of the image data of the partial detection region of the image sensor.

Abstract: A holding element for a drape for a surgical microscope is provided. The holding element has a holding ring and a recess located in the holding ring for an interface of the surgical microscope. The holding ring has an asymmetrical contour delimiting the recess such that in a condition in which the holding element is fastened to the surgical microscope there is only one possible fastening position of the holding element on the interface of the surgical microscope that corresponds to the contour of the holding ring, in which position an orientation of the holding element relative to the surgical microscope is defined.

Abstract: A microscopy system and a method for operating a microscopy system are provided. The microscopy system includes a tracking camera configured to detect a pose of an object, a tracking illumination device, and a controller configured to control the tracking illumination device and/or the tracking camera. Illumination information is determinable by evaluating an image representation from the tracking camera and/or pose information of the object is determinable relative to at least one illumination device and/or a working distance is determinable, with the illumination by the tracking illumination device and/or an image capture by the at least one tracking camera being able to be set based on the illumination information and/or based on the pose information of the object and/or based on the working distance.

Abstract: To simplify the optical calibration of an optical observation apparatus, a stand for an optical observation unit including a calibration object arranged directly on the stand in a fixed location is specified. Moreover, an optical observation apparatus, which includes such a stand and an optical observation unit connected to the stand, a method for calibrating such an optical observation apparatus, and a computer program are specified.

Abstract: A microscopy system includes a tracking camera for pose detection of a marker, a device configured to determine a working distance, a movable optical element, the pose of which can be changed to set a capture region of the tracking camera and/or at least two tracking illumination devices, at least one optical element for beam guidance of the radiation generated by the tracking illumination devices, and a controller configured to control the movable optical element and/or the tracking illumination devices, in which the pose of the movable optical element can be set based on the working distance and/or in which an operating mode and/or an illumination region of the tracking illumination devices can be set based on the working distance. In addition, a method for operating a microscopy system is provided.

Abstract: A holding element for a drape for a surgical microscope is provided. The holding element has a holding ring and a recess located in the holding ring for an interface of the surgical microscope. The holding ring has an asymmetrical contour delimiting the recess such that in a condition in which the holding element is fastened to the surgical microscope there is only one possible fastening position of the holding element on the interface of the surgical microscope that corresponds to the contour of the holding ring, in which position an orientation of the holding element relative to the surgical microscope is defined.

Abstract: A surgical microscope includes an image capture unit having an image sensor, a detection beam path, an image evaluation unit, a connection region for attaching a protective glass module with an objective protective glass. The image sensor has a detection region which has a used detection region for capturing the object region, and a partial detection region, which is not assigned to the used detection region. The image capture unit is configured such that, when the protective glass module with the objective protective glass is arranged at the connection region, a detail of the protective glass module with the objective protective glass is capturable by the partial detection region of the image sensor. The image evaluation unit is configured to generate a signal when an objective protective glass is detectable by the evaluation of the image data of the partial detection region of the image sensor.

Abstract: To simplify the optical calibration of an optical observation apparatus, a stand for an optical observation unit including a calibration object arranged directly on the stand in a fixed location is specified. Moreover, an optical observation apparatus, which includes such a stand and an optical observation unit connected to the stand, a method for calibrating such an optical observation apparatus, and a computer program are specified.

Abstract: The invention relates to an isolated, genetically modified, living non-mammal organism, having increased HMG-CoA-reductase activity compared to the wild type, and having reduced C24-methyltransferase and/or delta22-desaturase activity compared to the wild type. The invention is characterized in that the organism has increased dehydrocholesterol-delta70-reductase activity compared to the wild type. The invention further relates to different uses of such an organism, to a test kit comprising such an organism, and to a membrane extract of such an organism.

Abstract: The invention relates to an isolated, genetically modified, living non-mammal organism, having increased HMG-CoA-reductase activity compared to the wild type, and having reduced C24-methyltransferase and/or delta22-desaturase activity compared to the wild type. The invention is characterized in that the organism has increased dehydrocholesterol-delta70-reductase activity compared to the wild type. The invention further relates to different uses of such an organism, to a test kit comprising such an organism, and to a membrane extract of such an organism.

Abstract: The invention relates to an isolated, genetically modified, living non-mammal organism, having increased HMG-CoA-reductase activity compared to the wild type, and having reduced C24-methyltransferase and/or delta22-desaturase activity compared to the wild type. The invention is characterized in that the organism has increased dehydrocholesterol-delta70-reductase activity compared to the wild type. The invention further relates to different uses of such an organism, to a test kit comprising such an organism, and to a membrane extract of such an organism.

Abstract: The invention provides an isolated genetically modified non-mammalian organism, wherein the activity of acyl-CoA:sterol acyltransferase/sterol O-acyltransferase (EC 2.3.1.26) and/or diacylglycerol acyltransferase/diacylglycerol O-acyltranferase (EC 2.3.1.20) and/or lecithin cholesterol acyl transferase/phospholipid:diacylglycerol acyltransferase (EC 2.3.1.158) and/or acyl CoA-wax alcohol acyltransferase (EC 2.3.1.75) is reduced or abolished in comparison with a corresponding wildtype organism, methods of use of such an organism, shuttle vehicles for making such an organism and methods for producing such an organism.

Abstract: The invention relates to a microorganism, of the order of lactic acid bacteria or analog, fragment, derivative, mutant or combination thereof. Said microorganism, or analog, fragment, derivative, mutants or combinations thereof can be co-aggregated with at least Staphylococcus aureus or Pseudomonas aeruginosa.

Abstract: In a device for releasing a securing screw for a unit in a housing, in particular a pinion unit in a steering gear of a motor vehicle, the securing screw is connected via an external thread to an internal thread in the housing, wherein the securing screw is provided with a latching device, which has latching levers disposed distributed on the circumference of the securing screw, each of which said latching levers is provided with latching lugs disposed on the free ends of the latching levers. The latching lugs latch into teething gaps of a teething geometry of the housing. The latching devices can be connected to a tool in order to release the latching levers having the latching lugs from the latched position by means of a radially inwardly directed movement of the latching levers.

Abstract: The invention describes a microorganism of the order of lactic acid bacteria or an analog, fragment, derivative, mutant or combination thereof, wherein the microorganism, or analog, fragment, derivative, mutant or combination thereof can coaggregate with Streptococcus pyogenes.

Abstract: The present invention relates to a yeast cell, wherein said cell comprises a functional gene coding for soluble hydroxymethylglutaryl-coenzyme-A (HMG-CoA) reductase; one or more gene(s) coding for steryl acyltransferase(s) in said cell are defective or deleted; and said cell is prototrophic for at least histidine, leucine or uracil. Moreover, the present invention relates to the use of said cell for the production of one or more terpene(s). Further, the present invention relates to methods of generating said cell and the production of one or more terperne(s) and a pharmaceutical or cosmetically composition, a lubricant or transformer oil comprising said terpene(s).

Abstract: The invention relates to an isolated, genetically modified, living non-mammal organism, having increased HMG-CoA-reductase activity compared to the wild type, and having reduced C24-methyltransferase and/or delta22-desaturase activity compared to the wild type. The invention is characterized in that the organism has increased dehydrocholesterol-delta70-reductase activity compared to the wild type. The invention further relates to different uses of such an organism, to a test kit comprising such an organism, and to a membrane extract of such an organism.

Abstract: The invention provides an isolated genetically modified non-mammalian organism, wherein the activity of acyl-CoA:sterol acyltransferase/sterol O-acyltransferase (EC 2.3.1.26) and/or diacylglycerol acyltransferase/diacylglycerol O-acyltranferase (EC 2.3.1.20) and/or lecithin cholesterol acyl transferase/phospholipid: diacylglycerol acyltransferase (EC 2.3.1.158) and/or acyl CoA-wax alcohol acyltransferase (EC 2.3.1.75) is reduced or abolished in comparison with a corresponding wildtype organism, methods of use of such an organism, shuttle vehicles for making such an organism and methods for producing such an organism.

Abstract: The invention provides an isolated genetically modified non-mammalian organism, wherein the activity of acyl-CoA: sterol acyltransferase/sterol O-acyltransferase (EC 2.3.1.26) and/or diacylglycerol acyltransferase/diacylglycerol O-acyltranferase (EC 2.3.1.20) and/or lecithin cholesterol acyl transferase/phospholipid: diacylglycerol acyltransferase (EC 2.3.1.158) and/or acyl CoA-wax alcohol acyltransferase (EC 2.3.1.75) is reduced or abolished in comparison with a corresponding wildtype organism, methods of use of such an organism, shuttle vehicles for making such an organism and methods for producing such an organism.

Abstract: The invention relates to a microorganism, of the order of lactic acid bacteria or analog, fragment, derivative, mutant or combination thereof. Said microorganism, or analog, fragment, derivative, mutants or combinations thereof can be co-aggregated with at least Staphylococcus aureus or Pseudomonas aeruginosa.