Patents by Inventor Andreas ROLLER

Andreas ROLLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Predicting response to PD-1 axis inhibitors
    Patent number: 11513122
    Abstract: The invention is concerned with a method of predicting response to a PD-1 axis inhibitor such as anti-PD-L1 antibody by determining the abundance of dendritic cells (DCs) in a tumor tissue sample. The abundance of DCs characterized by enhanced expressions of XCR1, IRF8, BATF3 and FLT3 predicts clinical response to the PD-L1 blockade 5 treatment.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: November 29, 2022
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Christian Klein, Maud Léa Mayoux, Andreas Roller, Wei Xu
  • PREDICTING RESPONSE TO PD-1 AXIS INHIBITORS
    Publication number: 20190346444
    Abstract: The invention is concerned with a method of predicting response to a PD-1 axis inhibitor such as anti-PD-L1 antibody by determining the abundance of dendritic cells (DCs) in a tumor tissue sample. The abundance of DCs characterized by enhanced expressions of XCR1, IRF8, BATF3 and FLT3 predicts clinical response to the PD-L1 blockade treatment.
    Type: Application
    Filed: March 25, 2019
    Publication date: November 14, 2019
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Christian KLEIN, Maud Léa MAYOUX, Andreas ROLLER, Wei XU
  • Assembly for an exhaust system
    Patent number: 10364734
    Abstract: An assembly for an exhaust system comprises a housing having a jacket, an insert arranged in the interior of the housing and having at least one exhaust pipe, wherein the jacket has an opening, in particular a radial opening, through which the exhaust pipe is connectable to the exhaust system, wherein an adapter part is provided that is connected to the exhaust pipe, and wherein the adapter part has a contact section that contacts the inner side of the jacket around the opening.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: July 30, 2019
    Assignee: Friedrich Boysen GMBH & Co. KG
    Inventors: Ramazan Sahan, Andreas Roller, Volkmar Knipps
  • ASSEMBLY FOR AN EXHAUST SYSTEM
    Publication number: 20180038263
    Abstract: An assembly for an exhaust system comprises a housing having a jacket, an insert arranged in the interior of the housing and having at least one exhaust pipe, wherein the jacket has an opening, in particular a radial opening, through which the exhaust pipe is connectable to the exhaust system, wherein an adapter part is provided that is connected to the exhaust pipe, and wherein the adapter part has a contact section that contacts the inner side of the jacket around the opening.
    Type: Application
    Filed: August 2, 2017
    Publication date: February 8, 2018
    Inventors: Ramazan SAHAN, Andreas ROLLER, Volkmar KNIPPS