Abstract: The invention refers to a dosing apparatus (1) for dosing a composition (31), comprising: at least one box (2) for keeping the composition (31) or a capsule (43) containing the composition (31), a solution reservoir (3) for preparing a composition solution (4) with a pre-defined concentration of the composition (31) in solution, wherein the composition solution (4) with said pre-defined concentration of the composition (31) in solution can be further used as a use solution (34), at least one spray means (5) coupled to the box (2) for bringing the composition (31) being in the box (2) into contact with a solvent liquid, such that an amount of the composition (31) dissolves and the thus resulting composition solution (4) flows into the solution reservoir (3), at least one spray line (10), for feeding the spray means (5) with the solvent liquid, a supply line (6) comprising a liquid connection (7), for supplying fresh liquid, preferably water, to the solution reservoir (3), measuring means (14) for measuring the

Abstract: The present invention relates to a method of controlling a dispenser for dosing a product in a washing machine leading to an optimized dosing result, a dispenser controller programmed with an algorithm to execute the method of the present invention as well as to the use of said dispenser for controlling dosing of a product in a washing machine.

Abstract: The invention refers to a dosing apparatus (1) for dosing a composition (31), comprising: at least one box (2) for keeping the composition (31) or a capsule (43) containing the composition (31), a solution reservoir (3) for preparing a composition solution (4) with a pre-defined concentration of the composition (31) in solution, wherein the composition solution (4) with said pre-defined concentration of the composition (31) in solution can be further used as a use solution (34), at least one spray means (5) coupled to the box (2) for bringing the composition (31) being in the box (2) into contact with a solvent liquid, such that an amount of the composition (31) dissolves and the thus resulting composition solution (4) flows into the solution reservoir (3), at least one spray line (10), for feeding the spray means (5) with the solvent liquid, a supply line (6) comprising a liquid connection (7), for supplying fresh liquid, preferably water, to the solution reservoir (3), measuring means (14) for measuring the

Abstract: Provided are methods for detecting a target nucleic acid in a biological sample using RNA amplification. In an embodiment, provided is a method that comprises (a) amplifying a target nucleic acid, or portion thereof, using a primer comprising a sequence that is complementary to a polynucleotide sequence in the target nucleic acid, or a complement thereof, and a sequence that encodes an RNA polymerase promoter; (b) synthesizing RNA using an RNA polymerase that recognizes the promoter; and (c) detecting the presence or absence of the resulting RNA using mass spectrometry thereby detecting the presence or absence of the target nucleic acid in the biological sample.

Abstract: Fast and highly accurate mass spectrometry-based processes for detecting a particular nucleic acid sequence in a biological sample are provided. Depending on the sequence to be detected, the processes can be used, for example, to diagnose a genetic disease or chromosomal abnormality; a predisposition to a disease or condition, infection by a pathogenic organism, or for determining identity or heredity.

Abstract: Fast and highly accurate mass spectrometry-based processes for detecting a particular nucleic acid sequence in a biological sample are provided. Depending on the sequence to be detected, the processes can be used, for example, to diagnose a genetic disease or chromosomal abnormality; a predisposition to a disease or condition, infection by a pathogenic organism, or for determining identity or heredity.

Abstract: Fast and highly accurate mass spectrometry-based processes for detecting a particular nucleic acid sequence in a biological sample are provided. Depending on the sequence to be detected, the processes can be used, for example, to diagnose a genetic disease or chromosomal abnormality; a predisposition to a disease or condition, infection by a pathogenic organism, or for determining identity or heredity.

Abstract: Fast and highly accurate mass spectrometry-based processes for detecting a particular nucleic acid sequence in a biological sample are provided. Depending on the sequence to be detected, the processes can be used, for example, to diagnose a genetic disease or chromosomal abnormality; a predisposition to a disease or condition, infection by a pathogenic organism, or for determining identity or heredity.

Abstract: Processes, kits and preferred devices for rapidly isolating large numbers of plasmid DNAs from plasmid containing cells and for performing high throughput DNA sequencing are described.

Abstract: Processes and kits for simultaneously amplifying and sequencing nucleic acid molecules, and perfonning high throughput DNA sequencing are described.