Patents by Inventor Andreas Schoop

Andreas Schoop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • New dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
    Publication number: 20060046990
    Abstract: Disclosed are new dihydropteridinones of general formula (I) wherein the groups R1 to R5, Ra to Rc, W, Q1 and Q2 have the meanings given in the claims and specification, the isomers thereof and the use thereof for preparing a pharmaceutical composition for the treatment of diseases characterised by excessive or abnormal cell proliferation.
    Type: Application
    Filed: August 25, 2005
    Publication date: March 2, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Heinz Stadtmueller, Harald Engelhardt, Andreas Schoop, Martin Steegmaier, Matthias Hoffmann, Matthias Grauert
  • Cyclopentabenzofuran derivatives and their use
    Patent number: 6943182
    Abstract: The invention relates to cyclopentabenzofuran derivatives, process for their preparation, the use of cyclopentabenzofuran derivatives for the production of a medicament for the therapy of NF-?B-dependent diseases and medicaments which contain the cyclopentabenzofuran derivatives.
    Type: Grant
    Filed: May 30, 2002
    Date of Patent: September 13, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Walter Guarnieri, Thomas Jaetsch, Andreas Schoop, Jörg Baumgarten, Axel Kretschmer, Horst-Peter Antonicek
  • Pyrimidine derivatives
    Publication number: 20030171359
    Abstract: The present invention relates to trisubstituted pyrimidines of formula (I) 1
    Type: Application
    Filed: October 16, 2002
    Publication date: September 11, 2003
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Georg Dahmann, Frank Himmelsbach, Bernd Krist, Martin Lenter, Alexander Pautsch, Gisela Schnapp, Martin Steegmaier, Helmut Wittneben, Anthony S. Prokopowicz, Walter Spevak, Andreas Schoops, Steffen Steurer
  • Cyclopentabenzofuran derivatives and their use
    Publication number: 20030144334
    Abstract: The invention relates to cyclopentabenzofuran derivatives and their use preparation, the use of cyclopentabenzofuran derivatives for the production of a medicament for the therapy of NF-&kgr;B-dependent diseases and medicaments which contain the cyclopentabenzofuran derivatives.
    Type: Application
    Filed: May 30, 2002
    Publication date: July 31, 2003
    Inventors: Walter Guarnieri, Thomas Jaetsch, Andreas Schoop, Jorg Baumgarten, Axel Kretschmer, Horst-Peter Antonicek
  • &bgr;-phenylalanine derivatives as integrin antagonists
    Patent number: 6589972
    Abstract: The present invention relates to compounds of the general formula (1) wherein R4 is —SO2R4′, —COOR4″, —COR4′, —CONR4′2 or —CSNR4′2; R4′ is hydrogen, a substituted or unsubstituted alkyl or cycloalkyl residue, a substituted or unsubstituted aryl residue or a saturated or unsaturated, optionally substituted heterocyclic residue; R4″ is a substituted or unsubstituted alkyl or cycloalkyl residue, a substituted or unsubstituted aryl residue or a saturated or unsaturated, optionally substituted heterocyclic residue; L is a sulphonamide, amide, ether, ester, keto, urea, thioether, sulphoxide or sulphone unit optionally extended by one or two methylene groups; and X is N, O or S; and their physiologically acceptable salts and stereoisomers.
    Type: Grant
    Filed: May 30, 2001
    Date of Patent: July 8, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Schoop, Gerhard Mueller, Ulf Brueggemeier, Delf Schmidt, Beatrix Stelte-Ludwig, Joerg Keldenich
  • Novel cytostatic conjugates with integrin ligands
    Publication number: 20020193311
    Abstract: The present invention relates to cytostatics which have a tumour-specific action as a result of linkage to &agr;v&bgr;3 integrin antagonists via preferred linking units which can be selectively cleaved by elastase, i.e. by an enzyme which can especially be found in tumour tissue. The preferred linking units provide sufficient stability of the conjugate of cytostatic and &agr;v&bgr;3 integrin antagonist in biological fluids and, at the same time, the desired intracellular action within tumour cells as a result of its specific enzymatic or hydrolytic cleavability with release of the cytostatic.
    Type: Application
    Filed: March 8, 2002
    Publication date: December 19, 2002
    Inventors: Hans-Georg Lerchen, Jorg Baumgarten, Andreas Schoop, Markus Albers
  • Cytostatic-integrin conjugates having specifically cleavable linking units
    Publication number: 20020183256
    Abstract: The present invention relates to cytostatics which have a tumor-specific action as a result of linkage to &agr;v&bgr;3 integrin antagonists via preferred linking units which can be selevtively cleaved by enzymes such as metallo matrixproteases (MMPs), i.e. by enzymes which can especially be found in tumor tissue. The preferred linking units guarantee the serum stability of the conjugate of cytostatic and &agr;v&bgr;3 integrin antagonist and, at the same time, the desired intracellular action within tumor cells as a result of its specific enzymatic or hydrolytic cleavability with release of the cytostatic.
    Type: Application
    Filed: December 21, 2001
    Publication date: December 5, 2002
    Inventors: Hans-Georg Lerchen, Jorg Baumgarten, Oswald Lockhoff, Markus Albers, Andreas Schoop
  • Cyclopentabenzofuran derivatives and their use
    Patent number: 6420393
    Abstract: The invention relates to cyclopentabenzofuran derivatives, processes for their preparation, the use of cyclopentabenzofuran derivatives for the production of a medicament for the therapy of NF-&kgr;B-dependent diseases and medicaments which contain the cyclopentabenzofuran derivatives.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: July 16, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Walter Guarnieri, Thomas Jaetsch, Andreas Schoop, Jörg Baumgarten, Axel Kretschmer, Horst-Peter Antonicek
  • Beta-phenylalanine derivatives as integrin antagonists
    Publication number: 20010031788
    Abstract: The present invention relates to compounds of the general formula (1) 1
    Type: Application
    Filed: May 30, 2001
    Publication date: October 18, 2001
    Inventors: Andreas Schoop, Gerhard Mueller, Ulf Brueggemeier, Delf Schmidt, Beatrix Stelte-Ludwig, Joerg Keldenich
  • &bgr;-phenylalanine derivatives as integrin antagonists
    Patent number: 6291503
    Abstract: The present invention relates to compounds of the general formula (1) wherein R4 is —SO2R4, —COOR4′, —COR4′, —CONR4′2 or —CSNR4′2; R4′ is hydrogen, a substituted or unsubstituted alkyl or cycloalkyl residue, a substituted or unsubstituted aryl residue or a saturated or unsaturated, optionally substituted heterocyclic residue; R4″ is a substituted or unsubstituted alkyl or cycloalkyl residue, a substituted or unsubstituted aryl residue or a saturated or unsaturated, optionally substituted heterocyclic residue; L is a sulphonamide, amide, ether, ester, keto, urea, thioether, sulphoxide or sulphone unit optionally extended by one or two methylene groups; and X is N, O or S; and their physiologically acceptable salts and stereoisomers.
    Type: Grant
    Filed: January 15, 1999
    Date of Patent: September 18, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Schoop, Gerhard Mueller, Ulf Brueggemeier, Delf Schmidt, Beatrix Stelte-Ludwig, Joerg Keldenich