Patents by Inventor Andreas Sellmer

Andreas Sellmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis, pharmacology and use of new and selective FMS-like tyrosine kinase 3 (FLT3) FLT3 inhibitors
    Patent number: 11384076
    Abstract: The present invention relates to small molecule compounds of formula (I) and their use as FLT3 inhibitors for the treatment of various diseases, such as acute myeloid leukemia (AML). The present invention further relates to methods of synthesizing the compounds and methods of treatment.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: July 12, 2022
    Assignees: UNIVERSITÄT REGENSBURG, UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZ
    Inventors: Siavosh Mahboobi, Andreas Sellmer, Herwig Pongratz, Bernardette Pilsl, Oliver Krämer, Thomas Kindler, Mandy Beyer
  • SYNTHESIS, PHARMACOLOGY AND USE OF NEW AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) FLT3 INHIBITORS
    Publication number: 20200190075
    Abstract: The present invention relates to small molecule compounds of formula (I) and their use as FLT3 inhibitors for the treatment of various diseases, such as acute myeloid leukemia (AML). The present invention further relates to methods of synthesizing the compounds and methods of treatment.
    Type: Application
    Filed: August 9, 2018
    Publication date: June 18, 2020
    Inventors: SIAVOSH MAHBOOBI, ANDREAS SELLMER, HERWIG PONGRATZ, BERNARDETTE PILSL, OLIVER KRÄMER, THOMAS KINDLER, MANDY BEYER
  • HDAC6 inhibitors and their uses
    Patent number: 10106540
    Abstract: The present invention relates to small molecule compounds and their use as HDAC inhibitors and in the treatment of various diseases, such as cancer. The present invention further relates to methods of synthesizing the compounds and methods of treatment. H-L(HA), H is a head group selected from (head group 1), (head group 2), (head group 3), (head group 4), (head group 5) and (head group 6).
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: October 23, 2018
    Assignees: UNIVERSITÄT REGENSBURG, FRIEDRICH-SCHILLER-UNIVERSITÄT JENA, UNIVERSITÄTSKLINIKUM JENA
    Inventors: Siavosh Mahboobi, Andreas Sellmer, Herwig Pongratz, Michel Leonhardt, Oliver Krämer, Frank-Dietmar Böhmer, Gerhard Kelter
  • NOVEL HDAC6 INHIBITORS AND THEIR USES
    Publication number: 20170210743
    Abstract: The present invention relates to small molecule compounds and their use as HDAC inhibitors and in the treatment of various diseases, such as cancer. The present invention further relates to methods of synthesizing the compounds and methods of treatment. H-L(HA), H is a head group selected from (head group 1), (head group 2), (head group 3), (head group 4), (head group 5) and (head group 6).
    Type: Application
    Filed: August 4, 2015
    Publication date: July 27, 2017
    Inventors: Siavosh MAHBOOBI, Andreas SELLMER, Herwig PONGRATZ, Michel LEONHARDT, Oliver KRÄMER, Frank-Dietmar BÖHMER, Gerhard KELTER
  • NOVEL BIFUNCTIONAL COMPOUNDS WHICH INHIBIT PROTEIN KINASES AND HISTONE DEACETYLASES
    Publication number: 20110065734
    Abstract: The present invention relates to a bifunctional compound of formula I or its pharmaceutically acceptable salts or solvates A-L-B (I) wherein A is a histone deacetylase (HDAC) inhibitory moiety, L is a single bond or a linker group and B is a protein kinase inhibitory moiety. The bifunctional compound according to formula (I) is useful for the treatment of malignant and non-malignant neoplasia and diseases related to abnormal cell growth.
    Type: Application
    Filed: November 14, 2008
    Publication date: March 17, 2011
    Applicant: 4SC AG
    Inventors: Thomas Bar, Thomas Maier, Thomas Beckers, Thomas Clossek, Siavosh Mahboobi, Andreas Sellmer
  • Novel lapacho compounds and methods of use thereof
    Publication number: 20060142271
    Abstract: The invention provides new synthetic lapacho derivatives as well as methods of use thereof. These compounds can be used in pharmaceutical compositions for the treatment or prevention of cell proliferation disorders. These compounds can also be used in the treatment or prevention of psoriasis or cancer or precancerous conditions.
    Type: Application
    Filed: September 17, 2003
    Publication date: June 29, 2006
    Inventors: Klaus Muller, Andreas Sellmer, June Salvesen, Chiang Li, Youzhi Li, Xianggao Sun