Patents by Inventor Andreas Sewing

Andreas Sewing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF DEPOSITING DISCRETE HYDROXYAPATITE REGIONS ON MEDICAL IMPLANTS
    Publication number: 20110089041
    Abstract: A method for electrochemically depositing discrete regions of calcium phosphate onto a medical implant. The method includes providing an implant including at least one area having a metallic surface. At least a portion of the metallic surface is contacted with an electrolyte solution comprising calcium ions and phosphate ions. The metallic surface is used as a cathode, and an electrical potential is applied between the cathode and the electrolyte solution. The electrical potential is applied with a constant current density of from about 10 to about 50 mA/cm2 for a period of time of from about 1 to about 20 minutes. A plurality of discrete regions of needle-shaped hydroxyapatite crystals are electrochemically deposited onto the metallic surface.
    Type: Application
    Filed: October 19, 2009
    Publication date: April 21, 2011
    Applicant: Biomet Manufacturing Corp.
    Inventors: Gautam GUPTA, Andreas Sewing
  • Process for the coating for metallic implant materials
    Patent number: 7229545
    Abstract: A biomimetically produced bone-analogous coating, comprising organic and inorganic main constituents, is suitable for coating metallic implant materials of any desired surfaces. The coating comprises a collagen matrix mineralized with calcium phosphate.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: June 12, 2007
    Assignee: Biomet Deutschland GmbH
    Inventors: Andreas Sewing, Michel Dard, Sophie Roessler, Dieter Scharnweber, Hartmut Worch
  • Pyrrolo (2.1a)dihydroisoquinolines and their use as phosphodiesterase 10a inhibitors
    Patent number: 6930114
    Abstract: The present invention relates to pyrrolo[2.1-a]dihydroisoquinolines which are inhibitors of phosphodiesterase 10a and can be used for combating cancer.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: August 16, 2005
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Maria Theresia Niewöhner, Marcus Bauser, Jens-Kerim Ergüden, Dietmar Flubacher, Paul Naab, Thorsten-Oliver Repp, Jürgen Stoltefuss, Nils Burkhardt, Andrea Sewing, Michael Schauer, Karl-Heinz Schlemmer, Olaf Weber, Stephen J. Boyer, Mark Miglarese, Ulrich Niewöhner
  • Chitosan-coated metallic article, and process for the production thereof
    Publication number: 20050079198
    Abstract: The invention describes an article made from chitosan-coated metal, where an impermeable chitosan layer having a barrier action is present on the metal through electrochemical polarisation in a chitosan-containing solution. The incorporation of biologically active components into the chitosan coating enables the coating to be matched to various applications and the bio-compatibility of correspondingly modified surfaces to be increased. Metallic articles or surfaces coated in this way are used, for example, as material for medical implants.
    Type: Application
    Filed: August 16, 2004
    Publication date: April 14, 2005
    Inventors: Berthold Nies, Andreas Sewing, Dieter Scharnweber, Hartmut Worch, Rene Beutner
  • Pyrrolo (2.1a)dihydroisoquinolines and their use as phosphodiesterase 10a inhibitors
    Publication number: 20040138249
    Abstract: The present invention relates to pyrrolo[2.1-a]dihydroisoquinolines which are inhibitors of phosphodiesterase 10a and can be used for combating cancer.
    Type: Application
    Filed: February 9, 2004
    Publication date: July 15, 2004
    Inventors: Ulrich Niewohner, Maria Theresia Niewohner, Marcus Bauser, Jens-Kerim Erguden, Dietmar Flubacher, Paul Nabb, Thorsten-Oliver Repp, Jurgen Stoltefuss, Nils Burkhardt, Andrea Sewing, Michael Schauer, Karl-Heinz Schlemmer, Olaf Weber, Stephen J. Boyer, Mark Miglarese
  • Process for the coating for metallic implant materials
    Publication number: 20040033249
    Abstract: A biomimetically produced bone-analogous coating, comprising organic and inorganic main constituents, is suitable for coating metallic implant materials of any desired surfaces. The coating comprises a collagen matrix mineralized with calcium phosphate.
    Type: Application
    Filed: April 16, 2003
    Publication date: February 19, 2004
    Applicant: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Andreas Sewing, Michel Dard, Sophie Roessler, Dieter Scharnweber, Hartmut Worch
  • Pyrrolo[2.1-a]isoquinoline derivatives
    Publication number: 20030236276
    Abstract: The present invention relates to pyrrolo[2.1-a]isoquinolines which are inhibitors of phosphodiesterase 10a, a process for preparing these compounds and a method of treating cancer in humans and animals by administering these compounds.
    Type: Application
    Filed: August 5, 2002
    Publication date: December 25, 2003
    Inventors: Ulrich Niewohner, Maria Niewohner, Marcus Bauser, Jens-Kerim Erguden, Dietmar Flubacher, Paul Naab, Thorsten-Oliver Repp, Jurgen Stoltefuss, Nils Burkhardt, Andrea Sewing, Michael Schauer, Karl-Heinz Schlemmer, Olaf Weber, Stephen J. Boyer, Mark Miglarese, Jianmei Fan, Barton Phillips, Brian C. Raudenbush, Yamin Wang
  • Coating for metallic implant materials
    Publication number: 20020018798
    Abstract: A biomimetically produced bone-analogous coating, comprising organic and inorganic main constituents, is suitable for coating metallic implant materials of any desired surfaces. The coating comprises a collagen matrix mineralized with calcium phosphate.
    Type: Application
    Filed: June 21, 2001
    Publication date: February 14, 2002
    Applicant: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Andreas Sewing, Michel Dard, Sophie Rossler, Dieter Scharnweber, Hartmut Worch