Patents by Inventor Andreas Stoll

Andreas Stoll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
    Publication number: 20050075338
    Abstract: This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.
    Type: Application
    Filed: September 22, 2004
    Publication date: April 7, 2005
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Derek Lowe, Philip Wickens, Xin Ma, Mingbao Zhang, William Bullock, Philip Coish, Ingo Mugge, Andreas Stolle, Ming Wang, Yamin Wang, Chengzhi Zhang, Hai-Jun Zhang, Lei Zhu, Manami Tsutsumi, James Livingston
  • 4-AMINO-5,6-SUBSTITUTED THIOPHENO [2,3-D] PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND THEIR USE IN THE TREATMENT OR PREVENTION OF PDE7B-MEDIATED DISEASES AND CONDITIONS
    Patent number: 6849638
    Abstract: The invention relates to 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same and their use to treat or prevent diseases and conditions mediated by the phosphodiesterase enzyme 7B (PDE7B). Diseases and conditions mediated by PDE7B include osteoporosis, osteopenia and asthma.
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: February 1, 2005
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Andreas Stolle, Donald E. Bierer, Yuanwei Chen, Dongping Fan, Barry Hart, Mary Katherine Monahan, William J. Scott
  • Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
    Patent number: 6828335
    Abstract: This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: December 7, 2004
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Derek B. Lowe, Philip L. Wickens, Xin Ma, Mingbao Zhang, William H. Bullock, Philip D. G. Coish, Ingo A. Mugge, Andreas Stolle, Ming Wang, Yamin Wang, Chengzhi Zhang, Hai-Jun Zhang, Lei Zhu, Manami Tsutsumi, James N. Livingston
  • Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases
    Publication number: 20040235830
    Abstract: The invention relates to substituted cyclohexane derivates of formula (I), a method for the production thereof and the use thereof in medicaments, particularly for preventing and/or treating cardiovascular diseases, diseases of the urogenital tract and cerebrovascular diseases.
    Type: Application
    Filed: April 22, 2004
    Publication date: November 25, 2004
    Inventors: Susanne Rohrig, Andreas Stolle, Julio C. Castro-Palomino, Helmut Haning, Gabriele Handke-Erguden, Noemi Daviu-Folguera, Holger Paulsen, Josef Pernerstorfer, Stephan-Nicholas Wirtz, Henning Steinhagen, Wolfgang Thielemann, Erwin Bischoff, Ulrich Ebbinghaus-Kintscher, Peter Ellinghaus, Joachim Hutter, Thomas Krahn, Frank Wunder, Klemens Lustig, Joachim Schuhmacher, Frank Sussmeier
  • Substituted indoles, pharmaceutical compounds containing such indoles and their use as PPAR-&ggr; binding agents
    Patent number: 6787651
    Abstract: Disclosed are substituted indoles, pharmaceutical compositions containing such indoles, and their use in treating or preventing PPAR-&ggr; mediated diseases or conditions, such as osteopenia, osteoporosis, cancer, diabetes and atherosclerosis.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: September 7, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: Andreas Stolle, Jacques P. Dumas, William Carley, Philip D. G. Coish, Steven R. Magnuson, Yamin Wang, Dhanapalan Nagarathnam, Derek B. Lowe, Ning Su, William H. Bullock, Ann-Marie Campbell, Ning Qi, Jeremy L. Baryza, James H. Cook
  • Substituted &agr;, &bgr;-anellated butyrolactones
    Patent number: 6723718
    Abstract: The present invention relates to novel substituted &agr;,&bgr;-fused butyrolactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cerebral ischaemias, craniocerebral trauma, states of pain or CNS-mediated spasms.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: April 20, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Stolle, Horst-Peter Antonicek, Stephen Lensky, Arnd Voerste, Thomas Müller, Jörg Baumgarten, Karsten von dem Bruch, Gerhard Müller, Udo Stropp, Ervin Horváth, Jean-Marie-Viktor de Vry, Rudy Schreiber
  • Process for preparing arylaminopropanols
    Publication number: 20030225153
    Abstract: The invention relates to a process for preparing enantiomerically enriched aryl-aminopropanols and to their use and also to intermediates.
    Type: Application
    Filed: March 18, 2003
    Publication date: December 4, 2003
    Inventors: Markus Eckert, Claus Dreisbach, Boris Bosch, Andreas Stolle
  • Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
    Publication number: 20030216391
    Abstract: This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.
    Type: Application
    Filed: July 25, 2002
    Publication date: November 20, 2003
    Inventors: Derek B. Lowe, Philip L. Wickens, Xin Ma, Mingbao Zhang, William H. Bullock, Philip D.G. Coish, Ingo A. Mugge, Andreas Stolle, Ming Wang, Yamin Wang, Chengzhi Zhang, Hai-Jun Zhang, Lei Zhu, Manami Tsutsumi, James N. Livingston
  • Substituted alpha, beta-anellated butyrolactones
    Publication number: 20030158424
    Abstract: The present invention relates to novel substituted &agr;,&bgr;-fused butyrolactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cerebral ischaemias, craniocerebral trauma, states of pain or CNS-mediated spasms.
    Type: Application
    Filed: July 25, 2002
    Publication date: August 21, 2003
    Inventors: Andreas Stolle, Horst-Peter Antonicek, Stephen Lensky, Arnd Voerste, Thomas Muller, Jorg Baumgarten, Karsten von dem Bruch, Gerhard Muller, Udo Stropp, Ervin Horvath, Jean-Marie-Viktor de Vry, Rudy Schreiber
  • 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same, and their use in the treatment or prevention of PDE7B-mediated diseases and conditions
    Publication number: 20030119829
    Abstract: The invention relates to 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same and their use to treat or prevent diseases and conditions mediated by the phosphodiesterase enzyme 7B (PDE7B). Diseases and conditions mediated by PDE7B include osteoporosis, osteopenia and asthma.
    Type: Application
    Filed: April 29, 2002
    Publication date: June 26, 2003
    Inventors: Andreas Stolle, Donald E. Bierer, Yuanwei Chen, Dongping Fan Can, Barry Hart, Mary Katherine Monahan, William J. Scott
  • Substituted indoles, pharmaceutical compounds containing such indoles and their use as PPAR-gamma binding agents
    Publication number: 20030087902
    Abstract: Disclosed are substituted indoles, pharmaceutical compositions containing such indoles, and their use in treating or preventing PPAR-&ggr; mediated diseases or conditions, such as osteopenia, osteoporosis, cancer, diabetes and atherosclerosis.
    Type: Application
    Filed: October 9, 2001
    Publication date: May 8, 2003
    Inventors: Andreas Stolle, Jacques P. Dumas, William Carley, Philip D.G. Coish, Steven R. Magnuson, Yamin Wang, Dhanapalan Nagarathnam, Derek B. Lowe, Ning Su, William H. Bullock, Ann-Marie Campbell, Ning Qi, Jeremy L. Baryza, James H. Cook
  • Substituted &agr;, &bgr;-anellated butyrolactones
    Patent number: 6462074
    Abstract: The present invention relates to novel substituted (&agr;,&bgr;-fused butyrolactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cerebral ischaemias, craniocerebral trauma, states of pain or CNS-mediated spasms.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: October 8, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Stolle, Horst-Peter Antonicek, Stephen Lensky, Arnd Voerste, Thomas Müller, Jörg Baumgarten, Karsten von dem Bruch, Gerhard Müller, Udo Stropp, Ervin Horváth, Jean-Marie-Viktor de Vry, Rudy Schreiber
  • Substituted &bgr;,&ggr;-anellated lactones
    Patent number: 6433004
    Abstract: The present invention relates to novel substituted &bgr;,&ggr;-fused lactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cerebral ischaemias, craniocerebral trauma, states of pain or CNS-mediated spasms.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: August 13, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Stolle, Horst-Peter Antonicek, Stephen Lensky, Arnd Voerste, Thomas Müller, Jörg Baumgarten, Karsten von dem Bruch, Gerhard Müller, Udo Stropp, Ervin Horváth, Jean-Marie-Viktor de Vry, Rudy Schreiber
  • Substituted bicyclic lactones
    Patent number: 6376539
    Abstract: The present invention relates to novel substituted bicyclic lactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cerebral ischaemias, cranial cerebral trauma, states of pain or CNS-mediated spasms.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: April 23, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Stolle, Horst-Peter Antonicek, Stephen Lensky, Arnd Voerste, Thomas Müller, Jörg Baumgarten, Karsten von dem Bruch, Gerhard Müller, Udo Stropp, Ervin Horváth, Jean-Marie-Viktor de Vry, Rudy Schreiber
  • Heteroatom-containing benzocyclopentane-oxazolidinones
    Patent number: 6069160
    Abstract: The invention relates to heteroatom-containing benzocyclopentaneoxazolidinones, to processes for their preparation and their use as medicaments, especially as antibacterial medicaments.
    Type: Grant
    Filed: April 12, 1996
    Date of Patent: May 30, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Stolle, Dieter Habich, Stephan Bartel, Bernd Riedl, Martin Ruppelt, Hanno Wild, Rainer Endermann, Klaus-Dieter Bremm, Hein-Peter Kroll, Harald Labischinski, Klaus Schaller, Hans-Otto Werling
  • Agent for increasing the keeping quality of slaughtered-animal carcasses
    Patent number: 5989611
    Abstract: The invention concerns an agent for enhancing the keeping quality of bodies of slaughtered animals, parts of bodies of slaughtered animals, and hamburger patties, a process for the use thereof, and bodies of slaughtered animals, parts of bodies of slaughtered animals, and hamburger patties which are preserved according to the process.
    Type: Grant
    Filed: October 16, 1997
    Date of Patent: November 23, 1999
    Inventors: Heinz Stemmler, Jr., Andreas Stolle, Hans G. Liebich
  • Heteroaryl-oxazolidinones
    Patent number: 5922708
    Abstract: The invention relates to novel heteroaryl-oxazolidinones of the general formula (I): ##STR1## in which the substituents are as defined in the description, to processes for their preparation and to their use as drugs, especially as antibacterial drugs.
    Type: Grant
    Filed: February 3, 1997
    Date of Patent: July 13, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bernd Riedl, Dieter Habich, Andreas Stolle, Martin Ruppelt, Stephan Bartel, Walter Guarnieri, Rainer Endermann, Hein-Peter Kroll
  • Heteroatom-containing cyclopentanopyridyl-oxazolidinones
    Patent number: 5869659
    Abstract: The present invention relates to heteroatom-containing cyclopentanopyridyl-oxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.
    Type: Grant
    Filed: January 13, 1997
    Date of Patent: February 9, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Stolle, Dieter Habich, Bernd Riedl, Martin Ruppelt, Stephen Bartel, Walter Guarnieri, Hanno Wild, Rainer Endermann, Hein-Peter Kroll
  • 2-oxo- and 2-thio-1,2-dihydroquinolinyl-oxazolidinones
    Patent number: 5861413
    Abstract: The present invention relates to 2-oxo- and 2-thio-1,2-dihydroquinolinyl-oxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.
    Type: Grant
    Filed: January 9, 1997
    Date of Patent: January 19, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Dieter Habich, Andreas Stolle, Bernd Riedl, Martin Ruppelt, Stephan Bartel, Walter Guarnieri, Rainer Endermann, Hein-Peter Kroll
  • 6-membered nitrogen-containing heteroaryl-oxazolidinones
    Patent number: 5843967
    Abstract: The invention relates to 6-membered nitrogen-containing heteroaryloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.
    Type: Grant
    Filed: November 15, 1996
    Date of Patent: December 1, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bernd Riedl, Dieter Habich, Andreas Stolle, Hanno Wild, Rainer Endermann, Klaus Dieter Bremm, Hein-Peter Kroll, Harald Labischinski, Klaus Schaller, Hans-Otto Werling