Patents by Inventor Andreas Tebbe

Andreas Tebbe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Markers for susceptibility to an inhibitor of an Src-family kinase
    Patent number: 9328386
    Abstract: The present invention relates to a method for predicting the responsiveness of a mammalian tumor cell or cancer cell to an inhibitor of a kinase of the Src family, such as dasatinib, bosutinib, saracatinib or ponatinib. The present invention also provides for a method for predicting the responsiveness of an individual to an inhibitor of a kinase of the Src family, whereby the individual is suspected to suffer from cancer. These methods involve the evaluation of the status of integrin ?4, wherein said status is indicative for the responsiveness to the inhibitor. Furthermore, a kit useful for carrying out the methods described herein as well as an oligo—or polynucleotide and/or antibodies capable of detecting the expression level of integrin ?4 for predicting the responsiveness to the inhibitor are provided.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: May 3, 2016
    Assignee: Evotec (München) GmbH
    Inventors: Christoph Schaab, Klaus Godl, Martin Klammer, Andreas Tebbe, Stefan Müller
  • Proteome-wide quantification of small molecule binding to cellular target proteins
    Patent number: 8959984
    Abstract: This invention relates to methods for the evaluation and/or quantification of the binding affinity of small molecules or other compounds to target components contained within an analyte, such as target proteins contained within the proteome of a cell or tissue.
    Type: Grant
    Filed: September 26, 2008
    Date of Patent: February 24, 2015
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V.
    Inventors: Henrik Daub, Michaela Bairlein, Kirti Sharma, Klaus Godl, Andreas Tebbe, Christoph Weber
  • MARKERS FOR SUSCEPTIBILITY TO AN INHIBITOR OF AN SRC-FAMILY KINASE
    Publication number: 20140302172
    Abstract: The present invention relates to a method for predicting the responsiveness of a mammalian tumor cell or cancer cell to an inhibitor of a kinase of the Src family, such as dasatinib, bosutinib, saracatinib or ponatinib. The present invention also provides for a method for predicting the responsiveness of an individual to an inhibitor of a kinase of the Src family, whereby the individual is suspected to suffer from cancer. These methods involve the evaluation of the status of integrin ?4, wherein said status is indicative for the responsiveness to the inhibitor. Furthermore, a kit useful for carrying out the methods described herein as well as an oligo- or polynucleotide and/or antibodies capable of detecting the expression level of integrin ?4 for predicting the responsiveness to the inhibitor are provided.
    Type: Application
    Filed: August 16, 2012
    Publication date: October 9, 2014
    Inventors: Christoph Schaab, Klaus Godl, Martin Klammer, Andreas Tebbe, Stefan Müller
  • Proteome-Wide Quantification of Small Molecule Binding to Cellular Target Proteins
    Publication number: 20100279891
    Abstract: This invention relates to methods for the evaluation and/or quantification of the binding affinity of small molecules or other compounds to target components contained within an analyte, such as target proteins contained within the proteome of a cell or tissue.
    Type: Application
    Filed: September 26, 2008
    Publication date: November 4, 2010
    Inventors: Henrik Daub, Michaela Bairlein, Kirti Sharma, Klaus Godl, Andreas Tebbe, Christoph Weber