Abstract: The invention relates to substituted dihydropyrazolo pyrazine carboxamide derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.

Abstract: The present application relates to novel substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo[2,1-c][1,2,4]triazol-3-ones of formula (I), to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of lung inflammation disorders.

Abstract: The present application relates to novel substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo[2,1-c][1,2,4]triazol-3-ones, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of lung inflammation disorders.

Abstract: The present application relates to novel, chiral 2,5-disubstituted cyclopentanecarboxylic acid derivatives, to a method for their preparation, to their use on their own or in combinations for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diseases of the respiratory tracts, the lung and the cardiovascular system.

Abstract: The present application relates to novel 2,5-disubstituted cyclopentanecarboxylic acid derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of respiratory, pulmonary and cardiovascular disorders.

Abstract: The present application relates to novel 2,5-disubstituted cyclopentanecarboxylic acid derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of respiratory, pulmonary and cardiovascular disorders.

Abstract: A method of handling a data request by exporting data from at least one database to at least one receiver via an intermediary server, the intermediary server comprising at least one database adapter and a memory buffer for temporary storage of data, the method including the steps of transmitting a data request to the database, retrieving the data from the database and assigning it with a unique ID, transmitting the data and the unique ID to the intermediary server, passing the data through the database adapter to transform the data into receiver readable format and transmitting the transformed data and unique ID number to the receiver when the receiver is next enabled to receive the data. There is furthermore provided a computer implemented system for accessing databases operated by independent electronic processing devices.

Abstract: An arrangement is provided for digital transmission of information via lines between a line termination (1) of a telecommunication network and subscribers (Tln) connected to the line termination. At least one terminal of a subscriber (Tln) is connected to a network termination (2) via an electric line (L3). The network termination (2) is connected to the line termination (1) via a line (L2) having metallic conductors. The line termination (1) has a voltage source (SV) for supplying power to itself and to the network termination (2) and the subscriber (Tln) terminals. For increased reliability during operation, two separate power supply units (SVE1, SVE2) are arranged in the network termination (2). One of the two separate power supply units (SVE1, SVE2) powers active components of the network termination (2) and the other of the two separate power supply units (SVE1, SVE2) powers the subscriber (Tln) terminals.

Abstract: A controllable amplifier, which has two symmetrical outputs, at which two output signals mirror-symmetrical with respect to each other are present, is used for amplification of a burst signal. To achieve the largest possible eye opening of the signals to be fed to a comparator, a predetermined d.c. voltage difference for the formation of matched signals is adjusted for both output signals. After this, the arithmetic mean values of the two matched signals are formed and are fed to a second comparator. The output value of the second comparator is fed to an integrator, to which a reference voltage is also fed. In case of a deviation of the mean values of the two matched signals from each other, the amplifier is adjusted in a compensating direction by the integrator.

Abstract: A cervical support has an inherently stable support body of elastic foam material, provided with a covering of textile material, the free ends of which body overlap each other at the rear in a nape support region of the cervical support and can be detachably connected to each other. The nape support region is of greater height than a front, chin support region of the cervical support. For improved fit against the patient's body, and the relief of pressure thereagainst, the nape support region follows a path which is substantially partially circular or partially elliptical, and merges into jaw support regions which extend symmetrically and in mirror image relationship with respect to an imaginary longitudinal axis connecting the centers of the nape support region and the chin support region. Each jaw support region is of flat S-shape, which at a certain distance from the chin support region, is bowed towards the longitudinal axis.

Abstract: For controlling the level of electrical signals a circuit arrangement is formed with two series connected amplifiers. A first amplifier containing a first variable resistor, operates at maximum amplification when a low input signal level is received. A second amplifier comprises a series connection of a second variable resistor and a current-controlled voltage source with two complementary outputs. The outputs of the voltage source are connected to a comparator and a controller with two separate outputs. One of the controller outputs transmits a control signal while the other output simultaneously transmits a blocking signal. A first output of the controller is connected with the first variable resistor, while a second output of the controller is connected to the second variable resistor.

Abstract: A cervical support has a substantially inherently stable support member of resilient foam material, constructed to encircle the neck of a patient who is to wear the cervical support. The support member has overlapping free end parts which are releasably connectable to each other. Support elements are insertable into through radial openings of the support member, each support element having a shank having a mushroom-shaped head at one end and a large area head at its other end. The former head can be pressed into a disc or band partially embracing the outer surface of the support member. The support elements can be selectively removed from, or inserted into, the openings to provide local stiffening of the support member as required by the patient's condition.