Patents by Inventor Andreas Tobler

Andreas Tobler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11370835
    Abstract: Processes and methods of purifying or separating Single Domain Antigen Binding (SDAB) molecules that include one or more single binding domains (e.g., one or more nanobody molecules), substantially devoid of a complementary antibody domain and an immunoglobulin constant region, using Protein A-based affinity chromatography, are disclosed.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: June 28, 2022
    Assignee: Ablynx N.V.
    Inventors: Paul R. Brown, Scott Andreas Tobler, Andrew M. Wood, Austin Wayne Boesch
  • Publication number: 20220119873
    Abstract: This disclosure relates to methods and kits for karyotyping in which chromosomes are interrogated by amplifying loci that are not within copy number variable regions thereof.
    Type: Application
    Filed: November 2, 2021
    Publication date: April 21, 2022
    Inventors: Adam BROOMER, Kelly LI, Andreas TOBLER, Caifu CHEN, David KEYS
  • Patent number: 11193165
    Abstract: This disclosure relates to methods and kits for karyotyping in which chromosomes are interrogated by amplifying loci that are not within copy number variable regions thereof.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: December 7, 2021
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Adam Broomer, Kelly Li, Andreas Tobler, Caifu Chen, David Keys
  • Publication number: 20190144531
    Abstract: Processes and methods of purifying or separating Single Domain Antigen Binding (SDAB) molecules that include one or more single binding domains (e.g., one or more nanobody molecules), substantially devoid of a complementary antibody domain and an immunoglobulin constant region, using Protein A-based affinity chromatography, are disclosed.
    Type: Application
    Filed: September 26, 2018
    Publication date: May 16, 2019
    Applicant: Ablynx N.V.
    Inventors: Paul R. Brown, Scott Andreas Tobler, Andrew M. Wood, Austin Wayne Boesch
  • Patent number: 10118962
    Abstract: Processes and methods of purifying or separating Single Domain Antigen Binding (SDAB) molecules that include one or more single binding domains (e.g., one or more nanobody molecules), substantially devoid of a complementary antibody domain and an immunoglobulin constant region, using Protein A-based affinity chromatography, are disclosed.
    Type: Grant
    Filed: October 29, 2009
    Date of Patent: November 6, 2018
    Assignee: Ablynx N.V.
    Inventors: Paul R. Brown, Scott Andreas Tobler, Andrew M. Wood, Austin Wayne Boesch
  • Publication number: 20160251707
    Abstract: This disclosure relates to methods and kits for karyotyping in which chromosomes are interrogated by amplifying loci that are not within copy number variable regions thereof.
    Type: Application
    Filed: March 1, 2016
    Publication date: September 1, 2016
    Inventors: Adam BROOMER, Kelly Li, Andreas Tobler, Caifu Chen, David Keys
  • Publication number: 20100172894
    Abstract: Processes and methods of purifying or separating Single Domain Antigen Binding (SDAB) molecules that include one or more single binding domains (e.g., one or more nanobody molecules), substantially devoid of a complementary antibody domain and an immunoglobulin constant region, using Protein A-based affinity chromatography, are disclosed.
    Type: Application
    Filed: October 29, 2009
    Publication date: July 8, 2010
    Applicant: WYETH
    Inventors: Paul R. Brown, Scott Andreas Tobler, Andrew M. Wood, Austin Wayne Boesch
  • Publication number: 20060088825
    Abstract: The present invention is in the field of molecular biology and genetics. More specifically, the invention relates to human ?N p73, a novel gene associated with apoptosis regulation. The present invention provides and includes nucleic acid molecules, proteins and antibodies associated with ?N p73 and methods utilizing such agents, for example in gene isolation, gene analysis, the production of transformed cell lines, and transgenic cells modified to over- or under-express ?N p73. Moreover, the present invention includes use of the agents of the invention for the diagnosis, prevention and treatment of diseases associated with decreases or increased apoptosis.
    Type: Application
    Filed: September 17, 2002
    Publication date: April 27, 2006
    Inventors: Ian Hayes, Gennaro Melino, Vincenzo De Laurenzi, Daniela Barcaroli, Eleonora Candi, Francesca Bernassola, Andreas Tobler, Urban Novak
  • Patent number: 4511873
    Abstract: A current transformer for outdoor high-voltage installations which is insulated by pressurized gas includes a metallic top housing mounted to a hollow porcelain insulator. The top housing contains a primary conductor which is surrounded by coils of the secondary circuit. The secondary terminal leads are installed in a grounded lead-through tube which is disposed within the hollow porcelain insulator. In order to increase the dielectric strength of the current transformer, the space which is enclosed by the top housing and the porcelain insulator is divided into a high-pressure region and a low-pressure region, the former region including zones which are exposed to high voltages, in particular the interior of the top housing, and which are bounded throughout by metal and a mechanically strong insulating material, such as a casting region.
    Type: Grant
    Filed: July 8, 1983
    Date of Patent: April 16, 1985
    Assignee: BBC Brown, Boveri & Company, Limited
    Inventors: Manfred Baier, Andreas Tobler