Abstract: The present disclosure describes methods of dosing vapendavir or a pharmaceutically acceptable salt thereof to treat subject in need thereof, thereby treating the respiratory enterovirus infection, wherein the respiratory enterovirus infection may be a respiratory enterovirus infection. The subject may further have an underlying condition, and the methods of the present disclosure may be useful in preventing or reducing acute exacerbations of the underlying condition in the subject. Pharmaceutical formulations of vapendavir are also disclosed.

Abstract: The present disclosure describes a method of treating a respiratory enterovirus infection in a human subject with COPD which includes administering to the subject a therapeutically effective amount of vapendavir or a pharmaceutically acceptable salt thereof, thereby treating the respiratory enterovirus infection in the subject. Pharmaceutical formulations of vapendavir are also disclosed.

Abstract: The invention relates to a method for detecting an infection of a mammal with an acid-resistant microorganism comprising the following steps: (a) provision of an immunochromatographic test with a sample application area for the application of a stool sample of the mammal with an antigen and application of the stool sample, (b) incubation of the stool sample using (i) a first receptor under conditions permitting a complex formation of the antigen from the acid resistant microorganism with the receptor; or (ii) at least two different first receptors under conditions permitting a complex formation of the antigen from the acid-resistant microorganism with the at least two first receptors and wherein the first receptor according to (i) or the first receptors according to (ii) specifically bind(s) an antigen which shows, at least with some mammals, a structure after passage through the intestine that corresponds to the native structure or the structure against which a mammal produces antibodies against after being

Abstract: The present invention relates to a new solution for the preparation of stool samples for diagnostic tests. The solution allows samples to be prepared simply before use in an immunological detection process and also provides a high level of sensitivity, specificity and reproducibility of the tests. The solution must contain at least one buffer substance, one detergent and one blocking reagent. The Invention also relates to a process for the analysis of a stool sample for diagnostic purposes using the solution according to the invention.