Abstract: A method for manufacturing a drug-delivery composition includes providing at least one pharmaceutically active compound, a dry powder comprising at least a polymer, and an aqueous solution. The dry powder, the pharmaceutically active compound and the aqueous solution are mixed to form a paste-like or semi-solid drug-delivery composition, wherein the aqueous solution is added in an amount of less than or equal to twice the total dry mass of the dry powder.

Abstract: A method for manufacturing a drug-delivery composition includes providing at least a pharmaceutically active composition, providing a hydrophobic matrix; and mixing the hydrophobic matrix and the pharmaceutically active composition to form a paste-like or semi-solid drug-delivery composition.

Abstract: A drug-delivery composition includes an intermediate composition having a hydrophilic matrix of a cross-linked polymer in form of particles, and a pharmaceutically active composition distributed in the cross-linked polymer of the particles.

Abstract: A method for manufacturing a drug-delivery composition includes providing at least a pharmaceutically active composition, providing a hydrophobic matrix; and mixing the hydrophobic matrix and the pharmaceutically active composition to form a paste-like or semi-solid drug-delivery composition.

Abstract: Embodiments described herein relate to hydrophilic matrix material and sustained drug-delivery material, and their use in medical and cosmetic applications.

Abstract: A system and method for managing power flow in a fuel cell vehicle. The method provides a difference between a power limit signal and an actual power signal to a PI controller to generate a power offset signal. The method determines whether a fuel cell stack is able to provide enough power to satisfy a power request, and if so, adds the power request and the power offset signal to generate a stack power request signal to cause the upper power limit signal to move towards and be matched to the actual power signal. If the stack is not able to provide enough power to satisfy the load power request signal, the method subtracts the power offset signal from the power limit signal to provide a load limit signal to cause the actual stack power signal to move towards and be matched to the upper power limit signal.

Abstract: A system and method for determining fuel consumption and travel range of an electric hybrid vehicle, such as an electric hybrid fuel cell vehicle. The method includes converting the output current of a battery to a virtual consumed fuel consumption flow value and then adding the virtual consumed fuel consumption flow value to an actual consumed fuel value to get a total consumed fuel value that is then divided by the travelled distance of the vehicle to get the fuel consumption of the vehicle. The method also includes converting the SOC of the battery to a virtual available fuel value and then adding the virtual available fuel value to an actual available fuel value to get a total available fuel value that is then divided by the fuel consumption to get the travel range of the vehicle.

Abstract: A method for manufacturing a drug-delivery composition includes providing at least a pharmaceutically active composition, providing a hydrophobic matrix; and mixing the hydrophobic matrix and the pharmaceutically active composition to form a paste-like or semi-solid drug-delivery composition.

Abstract: A method for manufacturing a drug-delivery composition includes providing at least one pharmaceutically active compound, a dry powder comprising at least a polymer, and an aqueous solution. The dry powder, the pharmaceutically active compound and the aqueous solution are mixed to form a paste-like or semi-solid drug-delivery composition, wherein the aqueous solution is added in an amount of less than or equal to twice the total dry mass of the dry powder.

Abstract: A system and method for managing power flow in a fuel cell vehicle. The method provides a difference between a power limit signal and an actual power signal to a PI controller to generate a power offset signal. The method determines whether a fuel cell stack is able to provide enough power to satisfy a power request, and if so, adds the power request and the power offset signal to generate a stack power request signal to cause the upper power limit signal to move towards and be matched to the actual power signal. If the stack is not able to provide enough power to satisfy the load power request signal, the method subtracts the power offset signal from the power limit signal to provide a load limit signal to cause the actual stack power signal to move towards and be matched to the upper power limit signal.

Abstract: The starch composition comprises a cationic, cross-linked starch that is partly swollen and partly gelatinized. It has a gelatinization coefficient gT smaller than 0.7 with T the jet cooking temperature. The starch composition suitably comprises a wheat starch or a blend of a wheat starch and another starch, for instance a root or tuber starch.

Abstract: The present invention relates to a method for coating a surface of a substrate with a drug for sustained release: (i) providing a substrate with a surface to be coated, (ii) depositing at least one bilayer on at least a portion of said surface, wherein one layer of the bilayer comprises a polyelectrolyte and the other layer comprises a pharmaceutically active ingredient, and wherein the two layers of the bilayer are oppositely charged under conditions of the deposition and one layer of the bilayer has a substantially different net charge under physiological conditions. The invention also pertains to substrates with microscopic or macroscopic surfaces coated with the method according to the invention.

Abstract: A power request controller that prevents a power request signal to a fuel cell stack controller from providing more compressor air and hydrogen gas than is necessary to meet the current power demands of the vehicle. The stack controller generates a signal of the available current from the fuel cell stack. This signal and the measured current actually being drawn from the stack are received by a proportional-integral (P-I) controller in the power request controller. If the available stack current is significantly greater than the stack current being used, the P-I controller will provide an output signal that reduces the power request signal to the stack controller so that the current produced by the stack and the current being drawn from the stack are substantially the same. A transient detector turns off the P-I controller so that it does not reduce the power request signal during an up-power transient.

Abstract: The present invention relates to a method for preparing a drug-eluting implantable or insertable medical device comprising the steps of (i) providing a implantable or insertable medical device having a surface, (ii) depositing at least two oppositely charged polyelectrolyte layers on at least a portion of said surface to form a polyelectrolyte multilayer on the surface, and (iii) depositing one or more layers of particulate pharmaceutically active ingredient within said polyelectrolyte multilayer or on top of said polyelectrolyte multilayer. The invention also pertains to a drug-eluting implantable or insertable medical device obtained by such a method and the medical uses of such devices.

Abstract: The starch composition comprises a cationic, cross-linked starch that is partly swollen and partly gelatinized. It has a gelatinization coefficient gT smaller than 0.7 with T the jet cooking temperature. The starch composition suitably comprises a wheat starch or a blend of a wheat starch and another starch, for instance a root or tuber starch.

Abstract: The invention relates to a method for electron diffraction tomography in a Transmission Electron Microscope. Known methods involve using Scanning Transmission Electron Microscope, and use the scanned beam for STEM diffraction. The invention proposes to form the diffraction patterns with a stationary beam with a diameter slightly larger than the crystal, as a result of which a TEM without STEM unit can be used. Finding the crystal is done in TEM mode. Advantages of the method according to the invention are: a TEM without scanning unit can be used, and the diffraction volume is not depending on the orientation of the crystal, as the whole crystal is illuminated while obtaining the diffraction pattern.

Abstract: A method for manufacturing a drug-delivery composition includes providing at least one pharmaceutically active compound, a dry powder comprising at least a polymer, and an aqueous solution. The dry powder, the pharmaceutically active compound and the aqueous solution are mixed to form a paste-like or semi-solid drug-delivery composition, wherein the aqueous solution is added in an amount of less than or equal to twice the total dry mass of the dry powder.

Abstract: A method for manufacturing a drug-delivery composition includes providing at least a pharmaceutically active composition, providing a hydrophobic matrix; and mixing the hydrophobic matrix and the pharmaceutically active composition to form a paste-like or semi-solid drug-delivery composition.

Abstract: Grid members, namely a runner (10) and wall angle (400) for suspended ceiling grids, are disclosed. Certain embodiments of the runner and the wall angle have two web portions (28, 30) and at least one distinct indent portion (62) to define a space between the web portions. An adhesive (56) may be disposed within one or more of the indent portions (62) to adhere the two web portions (28, 30) to each other. Certain embodiments of the runner or wall angle have flange portions (32, 34) that may have indent portions as well. One or more of these indent portions may contain adhesive. Some embodiments of the runner or wall angle have overturned cap portions on the flange portions, and an adhesive may be placed between the overturned cap portions and upwardly facing surfaces of the flange portions.