Patents by Inventor Andreas Wack

Andreas Wack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TCR-independent activation of T cells
    Patent number: 8029792
    Abstract: A method for TCR-independent T cell activation which comprises the co-ligation of CD28 and CD81.
    Type: Grant
    Filed: May 8, 2006
    Date of Patent: October 4, 2011
    Assignee: Novartis Vaccines and Diagnostics SRL
    Inventors: Alessandro Serra, Andreas Wack
  • TCR-Independent Activation of T Cells
    Publication number: 20100062977
    Abstract: A method for TCR-independent T cell activation which comprises the co-ligation of CD28 and CD81.
    Type: Application
    Filed: May 8, 2006
    Publication date: March 11, 2010
    Inventors: Alessandro Serra, Andreas Wack
  • ZWITTERIONIZATION OF CAPSULAR SACCHARIDES
    Publication number: 20090136547
    Abstract: Capsular saccharides are typically anionic. In the invention, however, cationic groups are introduced, such that the modified saccharide has a repeating unit which includes both cationic and anionic groups. These cationic and anionic groups can be balanced to give a zwitterionic repeating unit. These modifications can convert a saccharide that is normally a T-independent antigen into one that can activate T cells without requiring conjugation to a carrier. Typically, the invention modifies an anionic bacterial capsular saccharide antigen by converting a neutral group in the saccharide into a cationic group e.g. to change —NHAc to —NH3+.
    Type: Application
    Filed: August 24, 2006
    Publication date: May 28, 2009
    Applicant: NOVARTIS VACCINES AND DIAGNOSTICS SRL
    Inventors: John Telford, Francesco Berti, Andreas Wack