Abstract: A holding device for a disc-shaped component, in particular for a wafer, as part of a manipulator of an X-ray inspection system is disclosed. The holding device includes an X-ray tube and a detector in which the position and orientation of the component can be corrected by radial clamps. The radial clamps exert a force in the direction of the center of the component in the plane thereof. Access to the component is enabled for the X-ray tube on one side of the component and allows for a free space on the other side of the component for the beam cone of the X-ray tube.

Abstract: An instruction configured to perform data conversion is executed. The executing the instruction includes determining that an overflow condition exists in a change of a value, specified by the instruction, from one data format to another data format. It is determined that an overflow result control of the instruction is set to a selected value. A result of executing the instruction is provided. The providing the result includes placing a chosen default value in a result location based on determining that the overflow condition exists and that the overflow result control is set to the selected value.

Abstract: An instruction is executed to obtain a result that includes an output value and a result sign code. At least one operation is performed on at least a portion of a source value to provide the output value. The source value is located in a source location which includes a source position to include the source value and a source sign position to include a sign code of the source value. One or more controls of the instruction, including a preserve sign control, are checked to determine the result sign code. Based on, at least, the value of the preserve sign control being set to enabled, the result sign code is the sign code in the source sign position unmodified. The unmodified sign code is provided as the result sign code. The result including the output value and the result sign code is provided.

Abstract: An instruction to perform validity testing of a source value is executed. The executing the instruction includes obtaining the source value using at least one field of the instruction and obtaining a plurality of test controls using a field of the instruction. The one or more test controls of the plurality of test controls are used to specify which digit positions of the source value are to be tested for validity and what codes are valid codes for the digit positions specified to be tested. Validity testing of at least a portion of the source value is performed based on the plurality of test controls obtained using the field of the instruction, and the performing the validity testing provides a result. The result is provided for use in further processing.

Abstract: An instruction to perform validity testing of a source value is executed. The executing the instruction includes obtaining the source value using at least one field of the instruction and performing validity testing of at least a portion of the source value. The performing the validity testing is based on one or more test controls obtained using a field of the instruction. The performing the validity testing determines whether a format of the at least the portion of the source value adheres to a data format variation specified by, at least, the one or more test controls. The performing the validity testing provides a result, and the result is provided for use in further processing.

Abstract: An instruction to perform validity testing of a source value is executed. The executing the instruction includes obtaining the source value using at least one field of the instruction and obtaining a plurality of test controls using a field of the instruction. The one or more test controls of the plurality of test controls are used to specify which digit positions of the source value are to be tested for validity and what codes are valid codes for the digit positions specified to be tested. Validity testing of at least a portion of the source value is performed based on the plurality of test controls obtained using the field of the instruction, and the performing the validity testing provides a result. The result is provided for use in further processing.

Abstract: A method of producing a lipid-encapsulated RNA nanoparticle, comprising the steps a) flowing an aqueous solution comprising an RNA through a 1st tube having an inner diameter (ID) of between about 0.1? and 0.132?; b) flowing an ethanol solution comprising lipids through a 2nd tube having an ID of between about 0.005? and 0.02? at one third the flow rate of the aqueous solution through the 1st tube, wherein the lipids comprise a cationic lipid; and c) mixing the ethanol solution with the aqueous solution by flowing the ethanol solution and the aqueous solution into a mixing module consisting of the 2nd tube perpendicularly joined to the 1st tube; wherein the mixing produces an output solution flowing in the 1st tube comprising a turbulent flow of the RNA and the lipids in between about 10% to 75% ethanol v/v, and wherein the lipid-encapsulated RNA nanoparticles have a bilayer structure.

Abstract: A stator for an electric machine includes a stator body having a large number of stator grooves, wherein, in each stator groove in the radial direction, a plurality of conductors are arranged one above the other. A plurality of spacing elements are configured to maintain a predetermined spacing between the conductors and a spacing of the respective conductors from a groove wall of the stator body, wherein, within the stator groove, respective cooling channels, which are at least partially delimited by the respective conductors, are kept free, whereby a cooling fluid can flow directly along the conductors, wherein each of the conductors has in the cross section thereof an angular form, and each of the corners of the angular form is supported by a respective spacing element against an additional conductor and/or the groove wall.

Abstract: A method of producing a lipid-encapsulated RNA nanoparticle, comprising the steps a) flowing an aqueous solution comprising an RNA through a 1st tube having an inner diameter (ID) of between about 0.1? and 0.132?; b) flowing an ethanol solution comprising lipids through a 2nd tube having an ID of between about 0.005? and 0.02? at one third the flow rate of the aqueous solution through the 1st tube, wherein the lipids comprise a cationic lipid; and c) mixing the ethanol solution with the aqueous solution by flowing the ethanol solution and the aqueous solution into a mixing module consisting of the 2nd tube perpendicularly joined to the 1st tube; wherein the mixing produces an output solution flowing in the 1st tube comprising a turbulent flow of the RNA and the lipids in between about 10% to 75% ethanol v/v, and wherein the lipid-encapsulated RNA nanoparticles have a bilayer structure.

Abstract: The invention relates to a method for the operational analysis of an engine and/or for calibrating a controller of the engine, in particular an internal combustion engine, wherein run-up occurs of test points defined by values of a plurality of predetermined operating parameters and selected from a multidimensional test space using a statistical experiment design, whereby at least one operating parameter is in each case changed from one test point to the next test point in a plurality of steps in the run-up of the test points, wherein operational measurements are performed at measurement points resulting from a respective increment and at the actual test points, whereby measurement data from the operational measurements for the analysis and calibration of the controller are output and continuously stored, as well as a corresponding system.

Abstract: A stator for an electric machine of a motor vehicle includes with a laminated core in which at least one cooling channel runs, through which a cooling fluid for cooling the stator can flow, and at least one winding which is held on the laminated core and has a winding head. At least one ring is provided which adjoins a laminated core at least partially in the axial direction of the stator, has at least one guide channel which is connected fluidically to the cooling channel and through which the cooling fluid from the cooling channel can flow as a result, which guide channel has at least one outlet opening which is directed towards the winding head and via which the cooling fluid which flows through the cooling channel can be discharged from the ring and can be sprayed against the winding head.

Abstract: A processor unit for multiply and accumulate (“MAC”) operations is provided. The present invention may include the processor unit having a plurality of MAC units for performing a set of MAC operations. The present invention may include each MAC unit having an execution unit and a one-write one-read (“1W/1R”) register file, where the 1W/1R register file may have at least one accumulator. The present invention may include the execution unit of each MAC unit being configured to perform a subset of MAC operations by computing a product of a set of values received from another register file of the processor unit and adding the computed product to the at least one accumulator. The present invention may include each MAC unit being configured to perform the respective subset of MAC operations in a single clock cycle.

Abstract: A method for honing a rotationally symmetric, non-cylindrical bore includes the steps of limiting the stroke of a honing tool between upper and lower reversal points, continoulsy detecting the actual diameter of the bore at all points along its length between the upper and lower reversal points, continuously comparing the actual diameter of the bore to a specified target diameters for at least one of the upper or lower reversal points, continuously limiting the stroke to regions of the bore in which the actual diameter is smaller than the target diameter, continuously limiting the stroke to regions of the bore in which the actual diameter is smaller than the target diameter, and reducing the stroke of the honing tool step-by-step based on the detected actual values of the diameter of the bore, so that it only the regions of the bore that are machined in which the actual diameter of the bore is smaller than the target diameter corresponding to the detected actual values of the diameter.

Abstract: According to various embodiments of the invention, a heat exchanger can have at least one duct for conveying a coolant, wherein the at least one duct has a first section and a second section, the first section being arranged in the at least one duct upstream relative to the second section, in relation to a flow direction of the coolant, the second section having a cross section area that is larger than a cross section area of the first section, such that a sublimation of the coolant in the second section is made possible.

Abstract: The present disclosure provides methods and intermediates for making Compound A or a pharmaceutical salt thereof, and/or a solvate of, which are useful as methods and intermediates for producing compounds for treating diseases and conditions related to mutant KIT and PDGFRA.

Abstract: A method of producing a lipid-encapsulated RNA nanoparticle, comprising the steps a) flowing an aqueous solution comprising an RNA through a 1st tube having an inner diameter (ID) of between about 0.1? and 0.132?; b) flowing an ethanol solution comprising lipids through a 2nd tube having an ID of between about 0.005? and 0.02? at one third the flow rate of the aqueous solution through the 1st tube, wherein the lipids comprise a cationic lipid; and c) mixing the ethanol solution with the aqueous solution by flowing the ethanol solution and the aqueous solution into a mixing module consisting of the 2nd tube perpendicularly joined to the 1st tube; wherein the mixing produces an output solution flowing in the 1st tube comprising a turbulent flow of the RNA and the lipids in between about 10% to 75% ethanol v/v, and wherein the lipid-encapsulated RNA nanoparticles have a bilayer structure.

Abstract: A computer system, processor, and method for processing information is disclosed that includes at least one computer processor; a main register file associated with the at least one processor, the main register file having a plurality of entries for storing data, one or more write ports to write data to the main register file entries, and one or more read ports to read data from the main register file entries; one or more execution units including a dense math execution unit; and at least one accumulator register file having a plurality of entries for storing data. The results of the dense math execution unit in an aspect are written to the accumulator register file, preferably to the same accumulator register file entry multiple times, and the data from the accumulator register file is written to the main register file.

Abstract: An exhaust muffler for an exhaust system of an internal combustion engine includes a muffler housing (12) with an outer shell (14) enclosing a muffler interior (22), through which exhaust gas can flow. An inner shell (54) is arranged in the muffler interior (22) and covers the outer shell (14) in at least some areas on an inner side (52) facing the muffler interior (22).

Abstract: Aspects include a compute array of a processor with mixed-precision numerical linear algebra support. A first precision and a first shape of a first input matrix and a second precision and a second shape of a second input matrix to the compute array are determined. A plurality of linear algebra operations is repeated in parallel within the compute array to update a result matrix in an accumulator register based on the first input matrix, the second input matrix, and a number of rank updates of the result matrix to store in the accumulator register.

Abstract: A computer system, processor, and method for processing information is disclosed that includes at least one computer processor; a main register file associated with the at least one processor, the main register file having a plurality of entries for storing data, one or more write ports to write data to the main register file entries, and one or more read ports to read data from the main register file entries; one or more execution units including a dense math execution unit; and at least one accumulator register file having a plurality of entries for storing data. The results of the dense math execution unit in an aspect are written to the accumulator register file, preferably to the same accumulator register file entry multiple times, and the data from the accumulator register file is written to the main register file.