Patents by Inventor Andreas Zisch

Andreas Zisch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzyme-mediated modification of fibrin for tissue engineering
    Publication number: 20040082513
    Abstract: Matrices covalently bound to bidomain peptides or proteins, produced recombinantly or synthetically, contain a transglutaminase substrate domain and a bioactive factor. The bioactive factor is preferably a growth factor, such as VEGF, growth factors from the TGF-&bgr; superfamily, PDGF, human growth hormone, IGF, and ephrin. Particularly preferred growth factors are TGF-&bgr;1, BMP 2; VEGF121 and PDGF AB. The matrix material is crosslinkable, and may form a gel. These compositions are useful for tissue repair and regeneration.
    Type: Application
    Filed: August 27, 2003
    Publication date: April 29, 2004
    Applicant: California Institute of Technology
    Inventors: Jeffrey Hubbell, Jason Schense, Andreas Zisch, Heike Hall
  • Enzyme-mediated modification of fibrin for tissue engineering
    Publication number: 20020168718
    Abstract: Matrices covalently bound to bidomain peptides or proteins, produced recombinantly or synthetically, contain a transglutaminase substrate domain and a bioactive factor. The bioactive factor is preferably a growth factor, such as VEGF, growth factors from the TGF-&bgr; superfamily, PDGF, human growth hormone, IGF, and ephrin. Particularly preferred growth factors are TGF-&bgr;1, BMP 2; VEGF121 and PDGF AB. The matrix material is crosslinkable, and may form a gel. These compositions are useful for tissue repair and regeneration.
    Type: Application
    Filed: December 18, 2001
    Publication date: November 14, 2002
    Applicant: California Institute of Technology
    Inventors: Jeffrey Hubbell, Jason Schense, Andreas Zisch, Heike Hall