Patents by Inventor Andreas Zophel

Andreas Zophel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies to interleukin-like epithelial-mesenchymal transition inducer (ILEI)
    Patent number: 7745585
    Abstract: The functional characterization of ILEI to be a novel cytokine involved in epithelial/mesenchymal transition and the identification of biologically active ILEI provides the basis for generating ILEI inhibitors, in particular anti-ILEI antibodies, that are useful in the therapy of cancer, fibrosis and COPD.
    Type: Grant
    Filed: September 2, 2004
    Date of Patent: June 29, 2010
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Andreas Zophel, Horst Johann Ahorn, Birgit Jung, Renate Konopitzky, Karl-Heinz Heider, Norbert Kraut, Peter Seither, Thomas Waerner, Hartmut Beug, Martin Jechlinger, Ido M. Tamir, Andreas Weith, Stefan Gruenert
  • Use of manganese superoxide dismutase (MN-SOD) for preparing pharmaceutical compositions for low-dose treatment of diseases
    Patent number: 5714143
    Abstract: The present invention relates to the use of pharmaceutical preparations containing manganese superoxide dismutase in a low dose for treating diseases and conditions caused by free oxygen radicals.
    Type: Grant
    Filed: September 9, 1993
    Date of Patent: February 3, 1998
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: David R. Blake, Ewa J. Dowling, Christian Lillie, Andreas Zophel
  • Human manganese superoxide dismutase (hMn-SOD)
    Patent number: 5589371
    Abstract: The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: December 31, 1996
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Konrad Heckl, Walter Spevak, Elinborg Ostermann, Andreas Zophel, Edeltraud Krystek, Ingrid Maurer-Fogy, Maria J. Wiche-Castanon, Christian Stratowa, Rudolf Hauptmann
  • Expression of mature proteinase 2A, the partial purification thereof and preparation of substrates having an inhibitory effect
    Patent number: 5559025
    Abstract: The invention relates to the expression of mature HRV proteinase 2A, the partial purification thereof and the preparation of substrates having an inhibitory effect.
    Type: Grant
    Filed: October 11, 1994
    Date of Patent: September 24, 1996
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Horst Ahorn, Ingrid Maurer-Fogy, Wolfgang Sommergruber, Andreas Zophel, Dieter Blaas, Ernst Kuchler, Hans-Dieter Liebig, Timothy Skern
  • Human manganese superoxide dismutase (hMn-SOD)
    Patent number: 5436162
    Abstract: The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
    Type: Grant
    Filed: September 15, 1992
    Date of Patent: July 25, 1995
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Konrad Heckl, Walter Spevak, Elinborg Ostermann, Andreas Zophel, Edeltraud Krystek, Ingrid Maurer-Fogy, Maria J. Wiche-Castanon, Christian Stratowa, Rudolf Hauptmann
  • Human manganese superoxide dismutase (hMn-SOD)
    Patent number: 5260204
    Abstract: The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
    Type: Grant
    Filed: September 15, 1992
    Date of Patent: November 9, 1993
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Konrad Heckl, Walter Spevak, Elinborg Ostermann, Andreas Zophel, Edeltraud Krystek, Ingrid Maurer-Fogy, Maria J. Wiche-Castanon, Christian Stratowa, Rudolf Hauptmann
  • Human manganese superoxide dismutase (hMn-SOD)
    Patent number: 5240847
    Abstract: The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
    Type: Grant
    Filed: March 11, 1988
    Date of Patent: August 31, 1993
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Konrad Heckl, Walter Spevak, Elinborg Ostermann, Andreas Zophel, Edeltraud Krystek, Ingrid Maurer-Fogy, Maria J. Wiche-Castanon, Christian Stratowa, Rudolf Hauptmann