Abstract: The present invention relates to a method for in vitro detection and/or monitoring of a disease in a sample, based on measurement of enzymatic activity of proteases activated and secreted upon disease development, to modified peptides used for the enzymatic detection of the proteases, the use of the peptides, a kit comprising such peptides and the use of ADAM-protease activity as a surrogate marker for disease burden and activity in infectious, inflammatory, and malignant diseases, such as HIV infection and melanoma.

Abstract: Memory address translation apparatus comprises page table access circuitry to access a page table to retrieve translation data; a translation data buffer to store one or more instances of the translation data, comprising: an array of storage locations arranged in rows and columns; a row buffer comprising a plurality of entries and comparison circuitry responsive to a key value dependent upon at least the initial memory address, to compare the key value with information stored in each of at least one key entry and an associated value entry for storing at least a representation of a corresponding output memory address, and to identify which of the at least one key entry, if any, is a matching key entry storing information matching the key value; and output circuitry to output, when there is a matching key entry, at least the representation of the output memory address.

Abstract: A light source module includes an array of illumination elements and a light diffusing material. The light source module is configured to receive a control signal for adjusting diffusion of light emitted from the light source module and in response adjust the amount of diffusion of light emitted from the light source module. A light source module may include a segmented light diffusing material where each segment is associated with an illumination element. And individual segments may have light diffusing properties that are different than other segments of the light diffusing material. Some illumination elements may emit light of a different color spectrum than other illumination elements, and a light diffusing material may scatter the different colored light to illuminate a scene with combinations of light of different colors. A light source module may be embedded in a mobile computing device.

Abstract: Systems and methods of real-time augmented visualization of anatomical features are disclosed herein. The systems and methods can use concurrently collected and/or preexisting data regarding an anatomical structure to present an image of the anatomical structure to an operator in virtual space as overlayed in real space. The systems and methods can include acquiring image data from an anatomical structure of a subject. Visual image data of the subject can then be received, including non-rigid deformation of the subject. The device pose of the ultrasound device in real space can be determined using device pose data. Image pose of the image data can then be determined in virtual space. Then, a perspective pose of the image of at least a portion of the anatomical structure in virtual space can be mapped to the subject in real space.

Abstract: An apparatus for automatic movement of sliding windows in a motor vehicle, comprising a d.c. electric motor that moves a window (F) so that it slides along guides, including an electronic control module for controlling the d.c. electric motor, in particular a microprocessor. The electronic control module measures a current (I) of the motor and a position (X) of the window (F), and drives reversal of operation of the electric motor if it is verified that the current (I) is higher than a threshold current (Ith) and the position (X) of the window (F) falls within a given zone (APZ) of a path (P) of movement of the window (F). The anti-pinch circuit device measures a back electromotive force (E; Em) of the motor, and the electronic control module calculates the position of the window (F) as a function of the back electromotive force (E; Em) of the motor.

Abstract: A method (30) for analog beamfinding performed by a device (1, 2) is provided. The method (30) comprises performing (31) one or more one-dimensional beam sweeps in a first direction, performing (32) one or more one-dimensional beam sweeps in a second direction, and determining (33) a two-dimensional beam based on at least one one-dimensional sweep in the first direction and at least one one-dimensional sweep in the second direction. A corresponding device (1, 2), computer program (42) and computer program product (41) are also provided.

Abstract: A light-emitting component includes a light-emitting chip and a housing including a plastic body and a reflector, the reflector includes an electrically conductive layer, the light-emitting chip includes a top side and an underside, the underside of the light-emitting chip is arranged on the plastic body, an electrical terminal on the top side of the light-emitting chip electrically conductively connects to the reflector by a bond wire, the underside of the light-emitting chip and the reflector are electrically insulated from one another, a conduction region is provided within the plastic body, thermal conductivity of the conduction region is greater than thermal conductivity of the plastic body, the conduction region adjoins the underside of the light-emitting chip, and the conduction region extends from the side of the plastic body facing the light-emitting chip as far as the side of the plastic body facing away from the light-emitting chip.

Abstract: A method for producing a security element formed as a lenticular flip, including a micro-optical layer, a carrier substrate and an image layer, wherein the image layer includes n images for n=1 to i which are visible from an n-th observation angle allocated to the n-th image, and wherein n is at least 1. The images are imaged on a photoresist with parallel light in contact print or by means of projection. After the photoresist is developed, an image layer which includes the i images is present.

Abstract: Systems and methods are described for extended foreign object detection (FOD) signal processing. In aspects, an oscillator reset is implemented in a FOD system to mitigate the effects of intermodulation products. In addition, dynamic frequency allocation is implemented to avoid high noise desensitizing the FOD system. Also, a slow sampling mode is implemented to increase a tolerance to transient foreign objects. Reference tracking and auto-recovery is implemented to bridge power outages. Additionally, the FOD system is configured to support position finding for determining an alignment between the vehicle pad and the base pad using a passive beacon transponder circuit and to perform beacon response cancellation as needed in concurrent FOD operation.

Abstract: A mesh handler for a mining machine includes a generally U-shaped frame arranged for receiving and positioning at least one mesh against a roof portion of an underground tunnel. The frame includes at least one generally U-shaped rail and a guide mechanism arranged for guiding the mesh along the rail in a direction substantially perpendicular to a longitudinal direction of the mining machine. Moreover, a mining machine including the mesh handler is provided.

Abstract: The invention is directed to a cutting post for mounting on a cutting apparatus and to the cutting apparatus. The cutting apparatus has at least one cutting blade and at least one cutting post. The cutting post includes at least one receptacle for the cutting blade and at least one cutting element having a cutting edge arranged at the head end of the cutting post. The cutting blade has a cutting blade edge and is held in the receptacle of the cutting post. The cutting blade edge of the cutting blade and the cutting edge of the cutting element of the cutting post conjointly form a continuous cutting contour.

Abstract: The present invention relates to immunomodulator compositions and methods of use as well as methods of making. The immunomodulator compositions comprise immunostimulatory plasmids, or DNA sequence, capable of eliciting an immune response in a recipient subject. Further, the immunostimulatory plasmids, or DNA sequence, do not contain antibiotic resistance coding sequence to help reduce the potential of horizontal transfer of antibiotic resistance in a population.

Abstract: The method according to the invention for producing a prestressed concrete workpiece is characterized in that the prestress is created by a heat treatment, wherein the concrete and the reinforcement therefor are selected in such a way that, when cooling the concrete workpiece from an elevated temperature, the heat expansion coefficient of the concrete is less than that of the reinforcement, and in that, during cooling, the concrete and the reinforcement adhere sufficiently strongly to one another if, during cooling, the concrete is hydrated at least to such an extent in order to be able to expand the reinforcement on account of the different heat expansion coefficients, and in that the concrete, together with the reinforcement, is brought to the elevated temperature in such a way that and is hydrated during cooling at least to such an extent that it is prestressed by the reinforcement after cooling.

Abstract: Embodiments of the present disclosure relate generally to improved braking systems for slide extractors. Slide extractors are generally used in aircraft galleys in order to move containers forward. The disclosed slide extractor braking system provides cooperation between magnets and corresponding conductive material in order to manage and appropriately slow retraction of the slide extractor in use.

Abstract: A problem addressed by embodiments of the invention disclosed herein consists in devising a connection device in which field terminations can be released also in the installed state, i.e., the electrical conductors can be manually disconnected using a simple tool even if the insulating body is already installed in an attachment housing. To this end, an actuator is proposed which has an inclined engagement portion with an adjoining engagement edge and engagement step by which the actuator can be lifted out of the insulating body, also from the cable connection side, with a slotted screwdriver in a single lifting movement.

Abstract: An assembly for an electric machine including a core with a plurality of teeth extending radially inward from the core, the plurality of teeth defining a plurality of slots for receiving coils, a plurality of coils, each coil wrapping around a respective tooth, a separator in one of the slots including a first leg joined at an angle to a second leg for separating adjacent coils within the slot, an insert between the first leg and the second leg for at least partially filling a space between the first leg and the second leg, and a potting filling space within the slot between the separator, the plurality of coils, and the insert.

Abstract: Disclosed is a pump dispenser comprising: a body defining a hollow interior and an opening through which at least a portion of a refill cartridge containing a flowable substance is receivable into the hollow interior; a lid; and a pump for pumping the flowable substance from the refill cartridge when the portion of the refill cartridge is in the hollow interior and the lid closes the opening. The lid comprises a dip tube with a lumen fluidly connected to the pump, the dip tube has a tapered end located in the hollow interior when the lid closes the opening. At least one of the body and the lid has a grip on an exterior surface thereof for aiding relative movement of the body and the lid to access the hollow interior when the lid closes the opening. Also disclosed is a system comprising the pump dispenser and the refill cartridge.

Abstract: A frequency-dependent damping valve arrangement of a vibration damper having a damping piston with at least one check valve, a control arrangement arranged coaxial to the damping piston including a control pot with a pot wall and a control piston axially displaceably arranged in the control pot that axially limits a control space. The control piston has a seal arrangement that seals the control piston relative to the pot wall including a circumferential groove formed at the control piston and a seal ring arranged therein. The seal arrangement is constructed such that this seal arrangement increases its sealing effect with rising damping medium pressure in the control space and reduces its sealing effect with falling damping medium pressure in the control space.