Abstract: A device for the hold-down and controlled release of space satellites installed on launchers and loads installed on space satellites, includes a blocking member made up of segments radially displaceable from a mutually approached retaining position to a mutually spaced-apart release position of a connecting screw. In order to control the radial displacement of the segments between the retaining position and the release position there are provided a rotatable element coaxial with the blocking member, an articulated mechanism which operatively connects the rotatable element with the segments of the blocking member, and linear motors for driving the controlled rotation of the rotatable element and, through the articulated mechanism, the simultaneous displacement of the segments of the blocking member.

Abstract: A vacuum device comprising at least one component having a portion which, during operation of the vacuum device, is in contact with a vacuum and which is coated at least in part by a layer which absorbs gas particles, in particular with a layer of a no-evaporable getter (NEG) material.

Abstract: A wireless sensor interface for a steering wheel is disclosed that includes a wireless sensor interface for a steering wheel with steering wheel components comprising a transmitter side with a wireless transmitter coil of a transmitter integrated circuit on a stationary printed circuit board and a receiver side with a wireless receiver coil of a receiver integrated circuit on a movable, rotating receiver printed circuit board, wherein the transmitter and receiver coils are mounted close to each other and concentric to a rotation axis of a steering column of the steering wheel, whereas an inductive coupling between the transmitter and receiver coils are used for wireless powering the steering wheel components and transmitting data of the steering wheel components back to the transmitter integrated circuit by means of modulating the received energy.

Abstract: The radionuclide 43Sc is produced at commercially significant yields and at specific activities and radionuclidic purities which are suitable for use in radiodiagnostic agents including imaging agents. In a method, a solid target having an isotopically enriched target layer prepared on an inert substrate is positioned in a specially configured target holder and irradiated with a charged-particle beam of protons or deuterons. The beam is generated using an accelerator such as a biomedical cyclotron at energies ranging from 3 to about 22. MeV. The method includes the use of three different nuclear reactions: a) irradiation of enriched 43Ca targets with protons to generate the radionuclide 43Scin the nuclear reaction 43Ca (p,n)43Sc, b) irradiation of enriched 42Ca targets with deuterons to generate the radionuclide 43Sc in the nuclear reaction 42Ca(d,n)43Sc, and c) irradiation of enriched 46Ti targets with protons to generate the radionuclide 43Sc in the nuclear reaction 46Ti (p,a) 43Sc.

Abstract: An electronic switching element (1) which comprises, in this sequence, a first electrode (16), a molecular layer (18) bonded to a substrate, and a second electrode (20), where the molecular layer essentially consists of compounds of the formula I indicated in claim 1, in which a mesogenic radical is bonded to the substrate via a spacer group (Sp) by means of an anchor group (G), is suitable for the production of components (1) as memristive device for digital information storage.

Abstract: A valve for metering a fluid is described, which is used, in particular, as a fuel injector for internal combustion engines, including an electromagnetic actuator and a valve needle actuatable by the actuator, an armature of the actuator being guided on valve needle, a stop element which limits a movement of the armature relative to the valve needle being situated on the valve needle, and the armature including a spring receptacle which is open toward the stop element and in which a spring supported on the stop element is inserted. The valve needle is guided via the armature and/or the stop element along a longitudinal axis of a housing. Furthermore, as viewed along the longitudinal axis, a length of the spring receptacle is smaller than a spring length of the spring in the non-actuated initial state.

Abstract: The present disclosure relates to various embodiments of aluminum alloy products having fine eutectic-type structures and methods for making the same. The method for producing an aluminum alloy product having a fine eutectic-type structure comprising selectively heating at least a portion of an additive manufacturing feedstock to a temperature above a liquidus temperature of the additive manufacturing feedstock, thereby forming a molten pool; and cooling the molten pool, thereby forming a solidified mass.

Abstract: A microscope arrangement includes a plurality of microscopes, and a control device having a display screen and a data link. The display screen is configured to show microscopy data of the microscopes via the data link using display symbols, each display symbol representing microscopy data received by the control device from a different one of the microscopes. In at least one operational state of the control device, the display symbols are moveable on the display screen to correspond to an arrangement of the microscopes.

Abstract: A thick matter pump includes a hydraulically-driven two-cylinder piston-pump configured to generate a thick matter delivery pressure. The thick matter pump also includes a hydraulic pump configured to apply hydraulic fluid to the two-cylinder piston-pump via a drive line. The hydraulic pump includes a pressure regulator that is adjustable to a target value of pressure of the hydraulic fluid for limiting the thick matter delivery pressure, and the thick matter delivery pressure is adjustably limited. The pressure of the hydraulic fluid is limited in the drive line, via an adjustable pressure-limiting valve, to an adjustable maximum pressure. The target pressure of the pressure regulator and the maximum pressure of the hydraulic fluid are adjustable through a joint adjusting element.

Abstract: A device for the hold-down and controlled release of space satellites installed on launchers and loads installed on space satellites, includes a blocking member made up of segments radially displaceable from a mutually approached retaining position to a mutually spaced-apart release position of a connecting screw. In order to control the radial displacement of the segments between the retaining position and the release position there are provided a rotatable element coaxial with the blocking member, an articulated mechanism which operatively connects the rotatable element with the segments of the blocking member, and linear motors for driving the controlled rotation of the rotatable element and, through the articulated mechanism, the simultaneous displacement of the segments of the blocking member.

Abstract: The present disclosure provides a method and an apparatus for producing astatine-211 from alpha-particle bombardment of bismuth-209. The disclosure also relates to a method and apparatus of producing other radionuclides from target nuclides. The apparatus includes a plate having a recessed portion. The recessed portion has a generally inert surface of ceramic or metal, preferably aluminium oxide that does not react with molten bismuth. A bismuth target is placed in the recessed portion and held therein by a foil cover. The foil has a melting temperature greater than target nuclide (i.e., for bismuth, >271° C.). The foil and target nuclide are held in the recessed portion by a cover that is fastened over the foil. The cover has an aperture to allow a beam of radiation, such as alpha particles, from a cyclotron or other accelerator to pass through the cover to the foil and target nuclide.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: An activity tracking device, such as a step-counting device includes an interface configured to receive one or more acceleration signals and signal processing circuitry. The signal processing circuitry generates an indication of condition of an accelerometer, such as a body position of the accelerometer, based on one or more accelerometer signals, generates an event signal, such as an event flag, based on one or more accelerometer signals and the indication of the condition of the accelerometer, and generates an activity signal, such as step flag based on the event signal, the indication of the condition of the accelerometer and one or more acceleration signals. The signal processing circuitry may generate a noise signal based on one or more acceleration signals and generate the activity signal based on the noise signal.

Abstract: It is disclosed an improved multi-step process for the preparation of a highly concentrated liquid formulation containing biomolecules comprising the steps of (a) a first ultrafiltration UF1; (b) a first diafiltration DF1; (c) a second diafiltration DF2; and (d) a second ultrafiltration UF2; wherein an aqueous solution of one or more salts, as liquid medium B, is used for step (b) and water or an aqueous solution of one or more salts, as liquid medium C, is used for step (c), wherein the one or more salts used for step (b) are the same or different from the one or more salts used for step (c) and wherein the liquid medium B has an ionic strength which is higher than the ionic strength of the liquid medium C. The process according to the present invention allows the preparation of well-defined highly concentrated formulations containing biomolecules, particularly proteins, intended for pharmaceutical or non-pharmaceutical use.

Abstract: Methods and devices are provided for use in a streaming process (130) of a Virtual Reality [VR] video to a VR rendering device (120). The streaming process has a configurable setup, each configured setup providing respective different image data of a scene. The VR rendering device is arranged to render a current view of the scene based on a current head position. The streaming process is executed according to a first configured setup providing first image data needed to render the current view. EEG data is determined by measuring brain signals (115) and a head movement is predicted based on the EEG data. Target image data is determined as needed for rendering a future view based on the predicted head movement. A new configured setup for providing the target image data is determined. By adapting the streaming process based on the prediction the target image data can be provided in time and efficiently using available bandwidth.

Abstract: A system for implementing virtual columns in a column store database is provided. In some implementations, the system performs operations including accessing a database table in a column store database system, the database table comprising at least one virtual column, the column store database system storing data in a column-oriented structure. The operations further include calculating a value for the at least one virtual column based on at least one existing column of the database table, the calculated value mapped to a row identifier associated with a row of the database table. The operations further include providing, in response to a query, the calculated value to a user interface, the query associated with the row identifier.

Abstract: A first moulding element is arranged on a vertical edge of a door leaf, and at least one second moulding element is arranged on a vertical strut of a door frame, wherein the first moulding element and the second moulding element intermesh automatically only in the closed position of the door leaf in such a manner that a direct or indirect form fit is automatically produced between the first moulding element and the second moulding element, as seen in a direction perpendicular to the plane of the door leaf, but such a form fit is automatically removed in a position of the door leaf differing from the closed position.

Abstract: A refrigeration appliance includes a case body and a door to be connected to the case body for sliding forwards and backwards. The door includes a front wall, a rear wall spaced from the front wall, a side wall interconnecting the front and rear walls, and an accommodating space formed and enclosed by the front, rear the side walls and filled with a heat insulation material. A power and/or signal transmission apparatus passes through a through hole in the rear wall and includes cables. A cable guiding member located in the accommodating space is used for guiding the cables. Not only can the cables be fixed conveniently and prevented from being stacked randomly in the accommodating space, but the cable guiding member can also guide the cables and provide conditions for power supply for wiring in the door.

Abstract: The invention relates to methods for determining whether a subject is afflicted with a motor neuron disease, the method comprising conducting an analysis of cerebrospinal fluid and/or plasma, measuring the level of one or more sterol/oxysterol analytes, and comparing these to reference values. Further, the invention relates to methods of identifying agents suitable for the treatment of MND, and monitoring the progress of the disease.

Abstract: The invention relates to an assembly comprising an electric component. The component has an electric part, a control circuit, and a capacitor. At least two lead frames are provided which are embedded into a housing. The part, the control circuit, and the capacitor are arranged on the lead frames, and the control circuit is designed to charge the capacitor and to supply the part with current from the capacitor in a clocked manner. The component has two contacts, and the component is arranged on a support. The support has an electrically conductive layer and the two contacts are connected to the layer in an electrically conductive manner. At least one first part of one lead frame is arranged at a greater distance from the electrically conductive layer than the second lead frame.