Abstract: A device for measuring a measured variable of a medium includes: a measuring cell, through which the medium can flow, in the inner chamber of which a channel opens on an inlet side and on an outlet side; a first duct opening into the inner chamber; a first component in the first duct such that an end portion of the first component projects into the inner chamber; and a first molded part, which surrounds on the end portion of the first component and a hollow chamber adjacent to the first component in the inner chamber, and includes, for each channel, a recess which connects the hollow chamber to the corresponding channel and is configured as a cross-sectional converter.

Abstract: A method for operating a damper valve in order to control a damper force of a damper in an active chassis of a vehicle, wherein the damper valve includes a pilot valve for controlling a main spool. The method includes determining a target pressure necessary for a target damper force, in a first damper chamber of the damper; determining a valve flow through a damper valve inlet of the damper valve on the basis of a damper flow, generated by a damper movement, from the first damper chamber and on the basis of a measured pump flow of a pump; determining a main spool opening distance in such a way that, with an applied main spool flow through the main spool opening distance, the target pressure is present as the back pressure in the first damper chamber.

Abstract: One or more example embodiments of the present invention relates to a detector module for an X-ray detector comprising a sensor layer in a stacked construction configured to convert incident X-ray radiation into electrical signals; a readout layer configured to read out the electrical signals from the sensor layer; and a heating layer, the heating layer including a plurality of heating elements spatially distributed in the heating layer and configured separately from one another for heating the sensor layer, and wherein the readout layer has for each heating element an associated activatable adapting unit via which each heating element is contacted for feeding in power and which is configured to adapt the power fed to each heating element.

Abstract: A vehicle, in particular motorcycle, includes a frame, handlebars with two handlebar grips and a communication unit with at least one sensor for the acquisition of data relating to the vehicle, and an interface for transmitting the acquired data. A handlebar protector is arranged, preferably centrally, between the handlebar grips and the communication unit is arranged underneath the handlebar protector or at least partially, preferably entirely, within the handlebar protector.

Abstract: A wheel information transfer apparatus, including: an information detection apparatus to detect and store wheel-related information; and an information transfer apparatus to transfer the wheel-related information over a transfer medium; in which the information transfer apparatus is configured to transfer at least a first portion of the wheel-related information parallel or quasi-parallel, and in which the information transfer apparatus is configured to transfer the at least first portion of the wheel-related information or a second portion of the wheel-related information serially within the parallel or quasi-parallel data transfer. Also described are a wheel information transfer method and a related vehicle.

Abstract: A dual-clutch transmission includes two clutches for respectively connecting an input shaft in a rotationally fixed manner to a sub-transmission input shaft. Two layshafts each have one output gear arranged coaxially with respect thereto. A first, second, and third forward idler gear are each arranged coaxially with respect to the one layshaft. A fourth and fifth forward idler gear are each arranged coaxially with respect to the other layshaft. One of the output gears is a larger output gear having a greater diameter or a greater number of teeth than the other, smaller output gear. The first forward idler gear forms a second gear stage, the second forward idler gear forms a third gear stage, etc. The gear stages have a decreasing transmission ratio in the order stated.

Abstract: Plastic powder for use as a building material for manufacturing a three-dimensional object by layer-by-layer melting and solidification by hardening of the building material at the positions corresponding to the cross-section of the three-dimensional object in the respective layer by exposure to radiation, preferably by exposure to NIR radiation, wherein the plastic powder comprises a dry blend of polymer-based particles and particles of a NIR absorber, wherein the NIR absorber comprises carbon black or is carbon black and wherein the weight percentage of carbon black in the total weight of polymer and carbon black particles is in the range of at least 0.02% and at most 0.45%, and/or wherein the carbon black has a mean primary particle diameter in the range of from 15 nm to 70 nm, preferably of at least 26 nm and/or at most 58 nm.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: A valve assembly with a valve body, which has a fluid passage designed as a fluid inlet and at least one fluid passage designed as a fluid outlet, is disclosed. A fluid chamber connecting the fluid inlet to the at least one fluid outlet is formed in the valve body. A movably mounted closing body is positioned in the fluid chamber. The closing body is guided axially and/or radially by at least one guide ball. The at least one guide ball is arranged between the closing body and a lateral delimitation of the fluid chamber. A fluid passage is formed in the radial direction of the valve body.

Abstract: A lens element and a one-piece contact apparatus having a lens element and a holding device for fixing a patient's eye to a laser applicator of an ophthalmological laser therapy system and a corresponding production method. The production method is conceptually simple and user-friendly and allows a high degree of automation while at the same time meeting the high requirements for mechanical and optical precision of the lens element. The lens element has an optically effective zone and a joining zone. The joining zone also has a functional zone for joining the lens element to a holding device which is arranged continuously circumferentially or interrupted circumferentially at the outer edge of the lens element. The contact apparatus includes a lens element and a holding device, which are permanently connected to one another, wherein the lens element and the holding device are not connected to one another by adhesive-bonding.

Abstract: The present invention relates to the system for measuring the slip of a tyre (10) with respect to a rim (20), on which said tyre (10) is mounted. In particular, said system comprises a first electronic device (1) and a second electronic device (2), each of which is configured at least to acquire, filter, store and send data, and a processing unit (3), external to said electronic devices (1, 2), configured at least to receive and process the data sent by each electronic device (1, 2), in order to measure said slip by measuring an angle (?) and comparing the value of this angle with respect to at a reference angle ?ref. The present invention also relates to method for measuring the slip of a tyre (10) with respect to a rim (20), on which said tyre (10) is mounted.

Abstract: The present invention provides ISVD polypeptide derivatives capable of binding coagulation Factor IX(a) and Factor X(a) which are highly potent and provide a sufficiently long half-life such to allow for effective subcutaneous—as well as peroral administration. The ISVD polypeptides derivatives disclosed herein are thus suitable for treatment of haemophilia A, haemophilia A with inhibitors and acquired haemophilia A by various routes of administration including subcutaneous and peroral administration.

Abstract: A method for operating an injection valve by determining an opening or closing time of the injection valve based on a sensor signal. The method includes: providing an evaluation point time series by sampling a sensor signal of a sensor of the injection valve; using a non-linear data-based first sub-model to obtain a first output vector based on the evaluation point time series, wherein each element of the first output vector is associated with a specific time; using a linear, data-based second sub-model to obtain a second output vector based on the evaluation point time series, wherein each element of the second output vector is associated with a specific time; limiting the time determined by the first output vector depending on the second output vector in order to obtain the opening or closing time.

Abstract: A small-sized, portable enclosure protects a gas sensor against degradation due to environmental exposure and changes in atmospheric conditions. The protective enclosure includes an inlet for introduction of a gas into the enclosure, an outlet for release of the gas upon completion of a sensing run, and at least one retractable filter that removes from the inflowing gas deleterious compounds that can compromise the integrity of the sensor or cause the sensor to degrade over time. The enclosure does not include any filters during the measurement phase of the sensing run in order to allow the gas sensor to accurately measure an unmodified gas mixture and/or analyte.

Abstract: A method for the spatial mapping of a model of a surgical tool onto a spatial position of the surgical tool includes a) providing a surgical tool having a working part and a marker in the form of a visual image on a surface; b) providing a tool model of the surgical tool; c) providing a viewing device configured to be carried by a user and including a camera configured to capture a view and to generate camera data representative of the view; d) creating a spatial model of a space viewed by the camera; e) bringing the surgical tool within the space viewed b y the camera; f) identifying a representation of the marker in the camera data; g) determining a position and rotation of the representation of the marker with respect to the spatial model, and h) creating a spatial mapping of the tool model in the spatial model.

Abstract: The present disclosure relates to a seal, such as a gasket, for sealing a gap in a housing, said gap extending around an inner chamber of the housing, and thus for sealing the inner chamber from an exterior of the housing, comprising at least one sealing layer. The present disclosure further relates to a frame seal that provides sealing between at least two components of the housing, for example a bottom part and a top part of the housing, for example of a motor vehicle battery housing or motor vehicle battery box housing.

Abstract: The systems, methods, and devices can efficiently express breast milk while being visually and audibly discreet, and portable. The breastmilk expression system for extracting milk from a breast of a female may include an interface configured to deliver suction to a nipple of the breast. The system may include a breastmilk storage container configured to store breastmilk. The system may include a control device operatively coupled to the breastmilk storage container and the interface. The control device may include one or more pressure reservoirs configured to store negative pressure. The control device may be configured to cause passive suction at the interface to cause extraction of the breast milk by controlling delivery of the negative pressure stored in the one or more pressure reservoirs to the interface.

Abstract: Provided herein are methods of using the antibodies that bind to RGMc to treat and diagnose iron-related disorders.

Abstract: A method of AI adjusting odds based on the context of the lineup in baseball or cricket. Specific examples include a batter likely to be pitched around because of who is up next and when a reliever is approaching his third batter faced (the minimum before he can be replaced).

Abstract: A gate driver circuit includes a pulse generator that receives an input signal and generates a pulse signal in response to a switch-on command included in the input signal. The pulse signal has a pulse with a pulse length that is dependent on a level of a pulse control signal. The circuit further includes a sampling circuit that samples an output voltage subsequent to the pulse and stores a respective sampled value, and a controller that receives the sampled value of the output voltage and a reference voltage and updates the level of the pulse control signal based on the sampled value and the reference voltage. A driver circuit generates the output voltage based on the pulse signal.