Patents by Inventor Andrei A. Zlota

Andrei A. Zlota has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of resolving amlodipine racemate
    Patent number: 6822099
    Abstract: The invention relates to methods of resolving racemic amlodipine into enantiomerically enriched compositions by precipitation with tartaric acid in the presence of a non-aqueous solvent, such as N,N′-dimethylacetamide. The molar ratio of tartaric acid:amlodipine is preferably less than 0.25:1.0 or greater than 0.75:1.0.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: November 23, 2004
    Assignee: Sepracor, Inc.
    Inventors: Chris H. Senanayake, Gerald J. Tanoury, Harold S. Wilkinson, Roger P. Bakale, Andrei A. Zlota
  • Method of resolving amlodipine racemate
    Publication number: 20030130321
    Abstract: The invention relates to methods of resolving racemic amlodipine into enantiomerically enriched compositions by precipitation with tartaric acid in the presence of a non-aqueous solvent, such as N,N′-dimethylacetamide. The molar ratio of tartaric acid:amlodipine is preferably less than 0.25:1.0 or greater than 0.75:1.0.
    Type: Application
    Filed: December 20, 2002
    Publication date: July 10, 2003
    Applicant: Sepracor, Inc.
    Inventors: Chris H. Senanayake, Gerald J. Tanoury, Harold S. Wilkinson, Roger P. Bakale, Andrei A. Zlota