Patents by Inventor Andrei Glinka

Andrei Glinka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECEPTORS OF RSPO2 AND RSPO3
    Publication number: 20170153246
    Abstract: The present invention relates to the finding that Syndecans (Sdc) are receptors of Rspondin-2 (Rspo2) and Rspondin-3 (Rspo3). Thus, the present invention relates to the identification of Rspo2, Rspo3 and/or Sdc activity modulators by determining if a test compound has the ability to modulate the binding of an Rspo2 and/or Rspo3 polypeptide to an Sdc polypeptide. Further, the invention refers to novel uses for antagonists of Rspo2 and/or Rspo3 in the treatment of Sdc-associated disorders and for Sdc antagonists in the treatment of Rspo2- and/or Rspo3-associated disorders.
    Type: Application
    Filed: February 10, 2017
    Publication date: June 1, 2017
    Applicant: Deutsches Krebsforschungszentrum
    Inventors: Christof NIEHRS, Andrei GLINKA, Bisei OKAWARA
  • RECEPTORS OF RSPO2 AND RSPO3
    Publication number: 20150362489
    Abstract: The present invention relates to the finding that Syndecans (Sdc) are receptors of Rspondin-2 (Rspo2) and Rspondin-3 (Rspo3). Thus, the present invention relates to the identification of Rspo2, Rspo3 and/or Sdc activity modulators by determining if a test compound has the ability to modulate the binding of an Rspo2 and/or Rspo3 polypeptide to an Sdc polypeptide. Further, the invention refers to novel uses for antagonists of Rspo2 and/or Rspo3 in the treatment of Sdc-associated disorders and for Sdc antagonists in the treatment of Rspo2- and/or Rspo3-associated disorders.
    Type: Application
    Filed: January 9, 2015
    Publication date: December 17, 2015
    Applicant: DEUTSCHES KREBSFORSCHUNGSZENTRUM
    Inventors: Christof NIEHRS, Andrei GLINKA, Bisei OKAWARA
  • Inhibitor protein of the wnt signal pathway
    Patent number: 8536311
    Abstract: The present invention relates to an inhibitor protein of the wnt signal path, a DNA encoding such a protein and a process for the preparation of such a protein. In addition, this invention concerns the use of the DNA and the protein as well as antibodies directed against the protein.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: September 17, 2013
    Assignee: Deutsches Krebsforschungszentrum Stiftung des Offentlichen Rechts
    Inventors: Christof Niehrs, Andrei Glinka
  • Inhibitor protein of the wnt signal pathway
    Patent number: 8461309
    Abstract: The present invention relates to an inhibitor protein of the wnt signal path, a DNA encoding such a protein and a process for the preparation of such a protein. In addition, this invention concerns the use of the DNA and the protein as well as antibodies directed against the protein.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: June 11, 2013
    Assignee: Deutsches Krebsforschungszentrum Stiftung des Offentlichen Rechts
    Inventors: Christof Niehrs, Andrei Glinka
  • RECEPTORS OF RSPO2 AND RSPO3
    Publication number: 20120263730
    Abstract: The present invention relates to the finding that Syndecans (Sdc) are receptors of Rspondin-2 (Rspo2) and Rspondin-3 (Rspo3). Thus, the present invention relates to the identification of Rspo2, Rspo3 and/or Sdc activity modulators by determining if a test compound has the ability to modulate the binding of an Rspo2 and/or Rspo3 polypeptide to an Sdc polypeptide. Further, the invention refers to novel uses for antagonists of Rspo2 and/or Rspo3 in the treatment of Sdc-associated disorders and for Sdc antagonists in the treatment of Rspo2- and/or Rspo3-associated disorders.
    Type: Application
    Filed: December 23, 2010
    Publication date: October 18, 2012
    Applicant: Deutsches Krebsforschungszentrum
    Inventors: Christof Niehrs, Andrei Glinka, Bisei Okawara
  • Inhibitor protein of the wnt signal pathway
    Publication number: 20110118445
    Abstract: The present invention relates to an inhibitor protein of the wnt signal path, a DNA encoding such a protein and a process for the preparation of such a protein. In addition, this invention concerns the use of the DNA and the protein as well as antibodies directed against the protein.
    Type: Application
    Filed: January 19, 2011
    Publication date: May 19, 2011
    Inventors: Christof Niehrs, Andrei Glinka
  • INHIBITOR PROTEIN OF THE WNT SIGNAL PATHWAY
    Publication number: 20070077244
    Abstract: The present invention relates to an inhibitor protein of the wnt signal path, a DNA encoding such a protein and a process for the preparation of such a protein. In addition, this invention concerns the use of the DNA and the protein as well as antibodies directed against the protein.
    Type: Application
    Filed: November 20, 2006
    Publication date: April 5, 2007
    Inventors: Christof Niehrs, Andrei Glinka
  • Inhibitor protein of the wnt signal pathway
    Patent number: 7138508
    Abstract: The present invention relates to an inhibitor protein of the wnt signal path, a DNA encoding such a protein and a process for the preparation of such a protein. In addition, this invention concerns the use of the DNA and the protein as well as antibodies directed against the protein.
    Type: Grant
    Filed: October 6, 2004
    Date of Patent: November 21, 2006
    Assignee: Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts
    Inventors: Christof Niehrs, Andrei Glinka
  • Inhibitor protein of the wnt signal pathway
    Publication number: 20050079173
    Abstract: The present invention relates to an inhibitor protein of the wnt signal path, a DNA encoding such a protein and a process for the preparation of such a protein. In addition, this invention concerns the use of the DNA and the protein as well as antibodies directed against the protein.
    Type: Application
    Filed: October 6, 2004
    Publication date: April 14, 2005
    Inventors: Christof Niehrs, Andrei Glinka
  • Inhibitor protein of the wnt signal pathway
    Patent number: 6844422
    Abstract: The present invention relates to an inhibitor protein of the wnt signal path, a DNA encoding such a protein and a process for the preparation of such a protein. In addition, this invention concerns the use of the DNA and the protein as well as antibodies directed against the protein.
    Type: Grant
    Filed: October 27, 1998
    Date of Patent: January 18, 2005
    Assignee: Deutsches Krebsforschungszentrum
    Inventors: Christof Niehrs, Andrei Glinka