Patents by Inventor Andrei Loas

Andrei Loas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E
    Publication number: 20250074942
    Abstract: This disclosure relates to synthetic peptides, peptidomimetics, and complexes of synthetic peptides and peptidomimetics with HLA-E, methods of making such peptides, peptidomimetics, and complexes, and methods of using such peptides, peptidomimetics and complexes for blocking, inhibiting, or preventing the interaction of HLA-E with CD94/NKG2A or activation of CD94/NKG2A by HLA-E. The synthetic peptides, peptidomimetics, and complexes of synthetic peptides and peptidomimetics with HLA-E can further comprise warheads to introduce covalent linkages between the synthetic peptides and peptidomimetics with HLA-E.
    Type: Application
    Filed: November 19, 2024
    Publication date: March 6, 2025
    Inventors: Magdalena Preciado Lopez, Dan L. Eaton, Clint Remarcik, John Wang, Nathalie M. Grob, Simon L. Rössler, Anthony J. Quartararo, Jason Tao, Andrei Loas, Stephen L. Buchwald, Bradley L. Pentelute, Ying Kit Jeffrey Wong
  • SARS-COV2 SPIKE PROTEIN BINDING PEPTIDES
    Publication number: 20230152316
    Abstract: The disclosure provides peptides that are useful for the prevention of infection of coronaviruses, especially SARS-CoV-2. Also described is a method reducing probability of viral infection in a human subject, comprising administering a therapeutically effective amount of the pharmaceutical composition described herein.
    Type: Application
    Filed: March 19, 2021
    Publication date: May 18, 2023
    Inventors: Bradley L. Pentelute, Genwei Zhang, Sebastian Pomplun, Alexander R. Loftis, Andrei Loas