Patents by Inventor Andrei PAVEL
Andrei PAVEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 12157627Abstract: A method of dislodging entrapped particulate material from an assembly of a bin and a hopper for dispensing the particulate material is disclosed. The method includes lifting at least one of a plurality of support legs off of the foundation by a predetermined amount by using at least one lifting mechanism that is resting on the foundation and operatively attached to one of the plurality of support legs; and dropping the at least one support leg into a free fall down on to the foundation using the lifting mechanism, whereby an impact shock thus produced is transmitted to the assembly of the bin and the hopper through the support leg and promote dislodging of any of the particulate material that may be in a non-flowable state to enhance dispensing of the particulate material from the assembly of the bin and the hopper.Type: GrantFiled: January 10, 2024Date of Patent: December 3, 2024Assignee: VALCO INDUSTRIES, INC.Inventors: Philip E. Risser, Logan Auker, Jake Byer, Andrei Pavel
-
Publication number: 20240150114Abstract: A method of dislodging entrapped particulate material from an assembly of a bin and a hopper for dispensing the particulate material is disclosed. The method includes lifting at least one of a plurality of support legs off of the foundation by a predetermined amount by using at least one lifting mechanism that is resting on the foundation and operatively attached to one of the plurality of support legs; and dropping the at least one support leg into a free fall down on to the foundation using the lifting mechanism, whereby an impact shock thus produced is transmitted to the assembly of the bin and the hopper through the support leg and promote dislodging of any of the particulate material that may be in a non-flowable state to enhance dispensing of the particulate material from the assembly of the bin and the hopper.Type: ApplicationFiled: January 10, 2024Publication date: May 9, 2024Applicant: Valco Industries, Inc.Inventors: Philip E. RISSER, Logan AUKER, Jake BYER, Andrei PAVEL
-
Patent number: 11926470Abstract: A lifting mechanism for operably attaching to one of the plurality of support legs on a bin is provided where the lifting mechanism is configured to sequentially lift and drop the support leg by a predetermined amount, whereby an impact shock generated by the drop is transmitted to the bin through the support leg and promote dislodging of any of the particulate material that may be in a non-flowable state to enhance dispensing of the particulate material from the bin. A bin assembly incorporating such lifting mechanism on at least one of its plurality of support legs is also disclosed.Type: GrantFiled: September 3, 2020Date of Patent: March 12, 2024Assignee: VALCO INDUSTRIES, INC.Inventors: Philip E. Risser, Logan Auker, Jake Byer, Andrei Pavel
-
Publication number: 20230159458Abstract: Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.Type: ApplicationFiled: August 3, 2022Publication date: May 25, 2023Applicant: AM Chemicals LLCInventors: Andrei Pavel GUZAEV, Vladimir Y. VVEDENSKIY, Khirud GOGOI
-
Patent number: 11447451Abstract: Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.Type: GrantFiled: May 19, 2020Date of Patent: September 20, 2022Assignee: AM Chemicals LLCInventors: Andrei Pavel Guzaev, Vladimir Y. VVedenskiy, Khirud Gogoi
-
Publication number: 20210061549Abstract: A lifting mechanism for operably attaching to one of the plurality of support legs on a bin is provided where the lifting mechanism is configured to sequentially lift and drop the support leg by a predetermined amount, whereby an impact shock generated by the drop is transmitted to the bin through the support leg and promote dislodging of any of the particulate material that may be in a non-flowable state to enhance dispensing of the particulate material from the bin. A bin assembly incorporating such lifting mechanism on at least one of its plurality of support legs is also disclosed.Type: ApplicationFiled: September 3, 2020Publication date: March 4, 2021Applicant: Valco Industries, Inc.Inventors: Philip E. RISSER, Logan AUKER, Jake BYER, Andrei PAVEL
-
Patent number: 10781175Abstract: Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.Type: GrantFiled: July 14, 2017Date of Patent: September 22, 2020Assignee: AM CHEMICALS LLCInventors: Andrei Pavel Guzaev, Vladimir Y. Vvedenskiy, Khirud Gogoi
-
Publication number: 20200277260Abstract: Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.Type: ApplicationFiled: May 19, 2020Publication date: September 3, 2020Applicant: AM Chemicals LLCInventors: Andrei Pavel Guzaev, Vladimir Y. VVedenskiy, Khirud Gogoi
-
Patent number: 10669301Abstract: Methods of preparing synthetic oligonucleotides containing at least one phosphotriester linkage conjugated to a monosaccharide are disclosed, where the synthetic oligonucleotides are prepared from nucleosidic phosphoramidite building blocks, preferably followed by removal of protecting groups to provide monosaccharide-conjugated oligonucleotides.Type: GrantFiled: August 30, 2018Date of Patent: June 2, 2020Assignee: AM CHEMICALS LLCInventors: Andrei Pavel Guzaev, Vladimir Y. Vvedenskiy
-
Publication number: 20180362572Abstract: Novel nucleoside phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one phosphotriester linkage conjugated to a monosaccharide and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said building blocks, preferably followed by removal of protecting groups to provide monosaccharide-conjugated oligonucleotides.Type: ApplicationFiled: August 30, 2018Publication date: December 20, 2018Applicant: AM CHEMICALS LLCInventors: Andrei Pavel GUZAEV, Vladimir Y. VVEDENSKIY
-
Patent number: 10087208Abstract: Novel nucleoside phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one phosphotriester linkage conjugated to a monosaccharide and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said building blocks, preferably followed by removal of protecting groups to provide monosaccharide-conjugated oligonucleotides.Type: GrantFiled: December 4, 2015Date of Patent: October 2, 2018Assignee: AM CHEMICALS LLCInventors: Andrei Pavel Guzaev, Vladimir Y. Vvedenskiy
-
Publication number: 20180016232Abstract: Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.Type: ApplicationFiled: July 14, 2017Publication date: January 18, 2018Applicant: AM Chemicals LLCInventors: Andrei Pavel GUZAEV, Vladimir V. VVEDENSKIY, Khirud GOGOI
-
Publication number: 20160083414Abstract: Novel nucleoside phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one phosphotriester linkage conjugated to a monosaccharide and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said building blocks, preferably followed by removal of protecting groups to provide monosaccharide-conjugated oligonucleotides.Type: ApplicationFiled: December 4, 2015Publication date: March 24, 2016Applicant: AM CHEMICALS LLCInventors: Andrei Pavel GUZAEV, Vladimir Y. VVEDENSKIY