Patents by Inventor Andrei Purmal

Andrei Purmal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS
    Publication number: 20190082845
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).
    Type: Application
    Filed: October 12, 2018
    Publication date: March 21, 2019
    Inventors: John TUCKER, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • Carbazole compounds and therapeutic uses of the compounds
    Patent number: 10137109
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: November 27, 2018
    Assignee: INCURON, INC.
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS
    Publication number: 20170165229
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).
    Type: Application
    Filed: December 21, 2016
    Publication date: June 15, 2017
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • Carbazole compounds and therapeutic uses of the compounds
    Patent number: 9566265
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: February 14, 2017
    Assignee: INCURON, LLC
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS
    Publication number: 20150342927
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).
    Type: Application
    Filed: June 4, 2015
    Publication date: December 3, 2015
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • Carbazole compounds and therapeutic uses of the compounds
    Patent number: 9108916
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: August 18, 2015
    Assignee: Incuron, LLC
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS
    Publication number: 20140303224
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).
    Type: Application
    Filed: April 1, 2014
    Publication date: October 9, 2014
    Applicant: Incuron, LLC
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • Carbazole compounds and therapeutic uses of the compounds
    Patent number: 8765738
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: July 1, 2014
    Assignee: Incuron, LLC
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • Carbazole Compounds and Therapeutic Uses of the Compounds
    Publication number: 20110305661
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases.
    Type: Application
    Filed: October 5, 2009
    Publication date: December 15, 2011
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • Method and composition for treating a biological sample
    Publication number: 20050074743
    Abstract: Disclosed are methods and compositions for treating biological samples, such as blood, to preserve or enhance the function of the samples.
    Type: Application
    Filed: October 6, 2003
    Publication date: April 7, 2005
    Inventors: Andrei Purmal, John Chapman, Jodie Tassello, Dimitry Kamen, C. Valeri
  • Methods for removing microbicidal compounds from compositions
    Publication number: 20040137419
    Abstract: Methods for removal of positively charged microbicidal compounds from biological compositions are provided.
    Type: Application
    Filed: October 6, 2003
    Publication date: July 15, 2004
    Applicant: V.I. Technologies, Inc.
    Inventors: Andrei Purmal, David Tabatadze
  • Method for purifying a biological composition
    Publication number: 20040077831
    Abstract: Disclosed is a method for removing an analyte from blood cells that results in a preparation of blood cells in which the level of the residual analyte is significantly reduced in the cell population. The method can be performed on large volume blood cell suspensions, and the cells prepared in this manner remain viable following prolonged storage and are suitable for therapeutic use, e.g. in transfusion applications. A preferred blood cell preparation is one that includes a red blood cell (RBC) population.
    Type: Application
    Filed: January 22, 2002
    Publication date: April 22, 2004
    Inventors: John Chapman, Andrei Purmal, James Hope
  • Methods to selectively inactivate parasites in biological compositions
    Publication number: 20040053208
    Abstract: The invention features a method for inactivating parasites in biological compositions. The method includes contacting the biological composition with an aziridino compound under parasite inactivating conditions.
    Type: Application
    Filed: June 27, 2003
    Publication date: March 18, 2004
    Applicant: V. I. Technologies, Inc.
    Inventors: Boris Zavizion, Andrei Purmal, Diana Serebryanik
  • Methods and reagents for extracorporeal immunomodulatory therapy
    Publication number: 20030149011
    Abstract: The invention features methods for altering the immunomodulatory activity of compositions containing peripheral blood mononuclear cells. The methods include the steps of contacting PBMCs with an amount of an aziridino-containing compound effective to react with and modify the PBMC nucleic acid.
    Type: Application
    Filed: November 6, 2001
    Publication date: August 7, 2003
    Inventors: Samuel Ackerman, Clark M. Edson, Loren Fast, Andrei Purmal
  • Method for purifying a biological composition
    Publication number: 20020131958
    Abstract: Disclosed is a method for reducing the amount of extracellular fluid in a blood cell suspension. The method includes providing a large volume of a blood cell suspension that includes blood cells and extracellular fluid. The blood cell suspension is washed with a wash solution under conditions sufficient to lower the concentration of the extracellular fluid in the blood cell composition at least 103-fold relative to the amount of extracellular fluid in the blood cell suspension. The method can also be used to lower the concentration of analytes (such as prions) in the blood cell suspension. Also provided is a blood cell suspension produced by the washing method.
    Type: Application
    Filed: September 4, 2001
    Publication date: September 19, 2002
    Inventors: John Chapman, Andrei Purmal, James Hope