Abstract: A wireless coil adaptor includes a first plug connector configured to be inserted within a receptacle connector of an MRI system, the receptacle connector being configured for receiving a second plug connector of a wired radio frequency (RF) coil. The wireless coil adaptor also includes a wireless communication module configured to wirelessly communicate with a wireless RF coil.

Abstract: An apparatus that is configured to stimulate hair growth (100) includes at least one electrode (101). The electrode includes projections such as pins or spikes which extend through the hair of the user and engage a portion of the surface of a user's skin without penetration of the skin. At least one detector (103) is operative to sense at least one condition corresponding to the amount of hair in an area on the user's skin adjacent to the detector. The at least one electrode and at least one detector are in operative connection with control circuitry (102). The control circuitry is operative responsive at least in part to the at least one sensed condition in the area to determine an electrical stimulation pattern (P1-P6) and to cause the electrode to stimulate the area in accordance with the determined pattern.

Abstract: A radio frequency (RF) coil assembly for a magnetic resonance (MR) system is provided. The RF coil assembly includes an RF coil array and a substrate assembly. The RF coil array includes one or more RF coils each RF coil including a coil loop that includes a wire conductor, the wire conductor formed into the coil loop. The substrate assembly includes a first substrate layer and a second substrate layer, wherein the first substrate layer is coupled with the second substrate layer at seams without a separately-provided fastening mechanism, wherein the RF coil array is positioned between the first substrate layer and the second substrate layer.

Abstract: The present invention relates to a method for culturing epidermis-derived stem cells comprising the step of culturing epidermis-derived stem cells in the presence of a three-dimensional extracellular matrix (3D-ECM) and a basal cell culture medium comprising: Epidermal Growth Factor (EGF); and/or a Vascular Endothelial Growth Factor (VEGF); and/or a Fibroblast Growth Factor (FGF); and further a ROCK (Rho-kinase) inhibitor. The present invention further relates to a method for ex vivo de novo generation of epidermis-derived stem cells. Furthermore, the present invention relates to an epidermis-derived stem cell that is obtainable by a method according to the present invention. Uses of said epidermis-derived stem cell, e.g. uses of said epidermis-derived stem cell for in vitro tissue production, in vitro drug discovery screening and medical applications, are also provided herein. The present invention further relates to a cell culture medium that is employed in the context of a method of the present invention.

Abstract: The invention relates to the field of biomedical and pharmacological research, in particular in the field of immunology, allergies, cancers, bone diseases and autoimmune diseases. The invention is based on the recent finding that SWAP-70 dimerizes, that the dimerization takes place via a specific, largely unique and limited region of the protein, and that this dimerization is central to the function of the protein (and probably the stability thereof). The invention provides a screening method which makes it possible to identify new active ingredients which, by accumulating at the dimerization domain and inhibiting SWAP-70 activity, suppress the supporting function of SWAP-70 in tumorigenesis, tumor cell migration and invasion, bone-degrading osteoclast activity, and the allergic reaction, as well as in autoimmune diseases.

Abstract: The invention relates to the field of biomedical and pharmacological research, in particular in the field of immunology, allergies, cancers, bone diseases and autoimmune diseases. The invention is based on the recent finding that SWAP-70 dimerises, that the dimerisation takes place via a specific, largely unique and limited region of the protein, and that this dimerisation is central to the function of the protein (and probably the stability thereof). The invention provides a screening method which makes it possible to identify new active ingredients which, by accumulating at the dimerisation domain and inhibiting SWAP-70 activity, suppress the supporting function of SWAP-70 in tumourigenesis, tumour cell migration and invasion, bone-degrading osteoclast activity, and the allergic reaction, as well as in autoimmune diseases.

Abstract: The present invention is directed to a drywall knife including a blade having an edge extending transversely to a longitudinal axis of the blade. A handle is attached to the blade, and a screwdriver tip is embedded within and rigidly attached to the handle. A dimple forming projection is attached to the handle and/or the screwdriver tip.