Patents by Inventor Andres Kink
Andres Kink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7970461Abstract: In one method, one or more excitation signals with the same or different frequencies are applied to a biological object such as a tissue, simultaneously or consequently. Response signals are then cross-correlated with delayed excitation signals. Cross-correlation products are then auto-correlated. Cross-correlation products correspond to conditions of the tissue and auto-correlation product corresponds to changes in the conditions. Measuring electrical characteristics at low, intermediate and high frequency is also disclosed. At low frequency, the current flows mostly through the extracellular liquid of tissue. At high frequency, the current passes through the cell membranes freely enough to dominate the overall impedance. At both frequencies, the delay is less than 1/30 of the period of the respective signal. The intermediate frequency between the low frequency and the high frequency carries information about quick changes in the condition of the tissue.Type: GrantFiled: June 20, 2005Date of Patent: June 28, 2011Inventors: Andres Kink, Mart Min, Toomas Parve, Indrek Ratsep
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Patent number: 7894900Abstract: A device for monitoring cardiac pacing rate having a measuring unit for receiving an electrical signal representing the patient's cardiac demand, and a computing unit for determining the myocardial energy balance by calculating energy consumed by the myocardium for both an external dynamic work for pumping blood into a vascular system, and an internal static work of the myocardium. Volume and time based measurements are used, and in one embodiment, volumes are estimated and volume ratios are calculated from volume estimates. In another embodiment, volumes are estimated from bioimpedance measurements. A further aspect is a rate adaptive pacemaker, wherein the maximum pacing rate is determined from the myocardial energy balance such that the energy supplied to the myocardium approximately equals the energy consumed by the myocardium for both an external dynamic work for pumping blood into a vascular system and an internal static work of the myocardium.Type: GrantFiled: August 30, 2007Date of Patent: February 22, 2011Assignee: Smartimplant OÜInventors: Andres Kink, Mart Minn, Toomas Parve, Indrek Rätsep
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Patent number: 7706872Abstract: A method of measuring of an electrical bio-impedance, the method being characterized in that a symmetrical bipolar pulse-form periodical excitation signal (electrical current or voltage) is applied to the input (11) of the bio-object (1), a corresponding reaction of the bio-object to the mentioned excitation signal is measured from the output (12), which is connected to the input (201) of the synchronous detector (200). A symmetrical bipolar pulse-form periodical signal is also applied to the reference input (202) of the synchronous detector (200), whereby both pulse-form signals are shortened by the predetermined time interval in each half period of the signal, said time intervals being different for the excitation and reference signals. The proposed method ensures an increased accuracy of the impedance analysis by decreasing the influence of the higher harmonics in the spectra of the excitation and reference signals of the synchronous detectors to the measurement result.Type: GrantFiled: November 28, 2003Date of Patent: April 27, 2010Assignee: Tallinn Technical UniversityInventors: Mart Min, Andres Kink, Raul Land, Toomas Parve
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Publication number: 20080058882Abstract: A device for monitoring cardiac pacing rate having a measuring unit for receiving an electrical signal representing the patient's cardiac demand, and a computing unit for determining the myocardial energy balance by calculating energy consumed by the myocardium for both an external dynamic work for pumping blood into a vascular system, and an internal static work of the myocardium. Volume and time based measurements are used, and in one embodiment, volumes are estimated and volume ratios are calculated from volume estimates. In another embodiment, volumes are estimated from bioimpedance measurements. A further aspect is a rate adaptive pacemaker, wherein the maximum pacing rate is determined from the myocardial energy balance such that the energy supplied to the myocardium approximately equals the energy consumed by the myocardium for both an external dynamic work for pumping blood into a vascular system and an internal static work of the myocardium.Type: ApplicationFiled: August 30, 2007Publication date: March 6, 2008Applicant: SMARTIMPLANT OUInventors: Andres Kink, Mart Min, Toomas Parve, Indrek Ratsep
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Publication number: 20060100539Abstract: A method of measuring of an electrical bio-impedance, the method being characterized in that a symmetrical bipolar pulse-form periodical excitation signal (electrical current or voltage) is applied to the input (11) of the bio-object (1), a corresponding reaction of the bio-object to the mentioned excitation signal is measured from the output (12), which is connected to the input (201) of the synchronous detector (200). A symmetrical bipolar pulse-form periodical signal is also applied to the reference input (202) of the synchronous detector (200), whereby both pulse-form signals are shortened by the predetermined time interval in each half period of the signal, said time intervals being different for the excitation and reference signals. The proposed method ensures an increased accuracy of the impedance analysis by decreasing the influence of the higher harmonics in the spectra of the excitation and reference signals of the synchronous detectors to the measurement result.Type: ApplicationFiled: November 28, 2003Publication date: May 11, 2006Inventors: Mart Min, Andres Kink, Raul Land, Toomas Parve
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Publication number: 20050283091Abstract: In one method, one or more excitation signals with the same or different frequencies are applied to a biological object such as a tissue, simultaneously or consequently. Response signals are then cross-correlated with delayed excitation signals. Cross-correlation products are then auto-correlated. Cross-correlation products correspond to conditions of the tissue and auto-correlation product corresponds to changes in the conditions. Measuring electrical characteristics at low, intermediate and high frequency is also disclosed. At low frequency, the current flows mostly through the extracellular liquid of tissue. At high frequency, the current passes through the cell membranes freely enough to dominate the overall impedance. At both frequencies, the delay is less than 1/30 of the period of the respective signal. The intermediate frequency between the low frequency and the high frequency carries information about quick changes in the condition of the tissue.Type: ApplicationFiled: June 20, 2005Publication date: December 22, 2005Applicants: TALLINN UNIVERSITY OF TECHNOLOGY, Smartimplant OUInventors: Andres Kink, Mart Min, Toomas Parve, Indrek Ratsep
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Patent number: 6975903Abstract: A rate adaptive pacemaker comprises a means (2) for determining the demand of the patient's organism, a pacing rate controlling means (16) for controlling the pacing rate in response to the patient's demand, and a pacing rate limiting means (20) for preventing the pacing rate from becoming too low. The pacing rate limiting means is adapted to limit the pacing rate downwards such that a first predetermined relation is satisfied between actual cardiac output (CO) and cardiac output (COrest) for the patient in rest conditions and a second predetermined relation is satisfied between actual stroke volume (SV) and rest stroke volume (SVrest).Type: GrantFiled: March 23, 2000Date of Patent: December 13, 2005Assignee: St. Jude Medical ABInventors: Mart Min, Andres Kink, Toomas Parve
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Patent number: 6885892Abstract: A rate adaptive pacemaker has a measuring unit which interacts with a patient to determine a demand, a pacing rate controller connected to the measuring unit for controlling the pacing rate in response to the demand, and a pacing rate limiter connected to the pacing rate controller which upwardly limits the pacing rate so as to always maintain the energy supplied to the myocardium at a level which exceeds the energy consumed by the myocardium.Type: GrantFiled: March 23, 2000Date of Patent: April 26, 2005Assignee: St. Jude Medical ABInventors: Mart Min, Andres Kink, Toomas Parve