Patents by Inventor Andres McAllister-Moreno

Andres McAllister-Moreno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant bicistronic flaviviruses and methods of use thereof
    Patent number: 8163548
    Abstract: The present invention provides recombinant bicistronic flaviviruses, particularly live attenuated recombinant bicistronic flavivirus, which comprise, in order from 5? to 3?, a viral 5?UTR, an ORF encoding all viral proteins, an internal ribosome entry site, an exogenous nucleotide sequence that encodes an exogenous polypeptide, and a viral 3?UTR. Infection of a host cell with a recombinant flavivirus provides for expression of the exogenous nucleic acid in a host cell. Such recombinant flavivirus are useful for delivering a protein to a mammalian host; and for eliciting an immune response to the exogenous polypeptide.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: April 24, 2012
    Assignee: The Regents of the University of California
    Inventors: Raul Andino-Pavlovsky, Andres McAllister-Moreno
  • Recombinant Bicistronic Flaviviruses and Methods of Use Thereof
    Publication number: 20110135682
    Abstract: The present invention provides recombinant bicistronic flaviviruses, particularly live attenuated recombinant bicistronic flavivirus, which comprise, in order from 5? to 3?, a viral 5?UTR, an ORF encoding all viral proteins, an internal ribosome entry site, an exogenous nucleotide sequence that encodes an exogenous polypeptide, and a viral 3?UTR. Infection of a host cell with a recombinant flavivirus provides for expression of the exogenous nucleic acid in a host cell. Such recombinant flavivirus are useful for delivering a protein to a mammalian host; and for eliciting an immune response to the exogenous polypeptide.
    Type: Application
    Filed: November 23, 2010
    Publication date: June 9, 2011
    Applicant: The Regents of the University of California
    Inventors: RAUL ANDINO-PAVLOVSKY, ANDRES MCALLISTER-MORENO
  • Recombinant bicistronic flaviviruses and methods of use thereof
    Patent number: 7871814
    Abstract: The present invention provides recombinant bicistronic flaviviruses, particularly live attenuated recombinant bicistronic flavivirus, which comprise, in order from 5? to 3?, a viral 5?UTR, an ORF encoding all viral proteins, an internal ribosome entry site, an exogenous nucleotide sequence that encodes an exogenous polypeptide, and a viral 3?UTR. Infection of a host cell with a recombinant flavivirus provides for expression of the exogenous nucleic acid in a host cell. Such recombinant flavivirus are useful for delivering a protein to a mammalian host; and for eliciting an immune response to the exogenous polypeptide.
    Type: Grant
    Filed: May 9, 2002
    Date of Patent: January 18, 2011
    Assignee: The Regents of the University of California
    Inventors: Raul Andino-Pavlovsky, Andres McAllister-Moreno
  • Recombinant yellow fever virus and methods of use thereof
    Patent number: 6893643
    Abstract: The present invention provides recombinant yellow fever viruses (YFV), particularly live attenuated recombinant YFV, which comprise exogenous (i.e., non-YFV) nucleotide sequences which encode exogenous (i.e., non-YFV) amino acid sequences. These recombinant YFV viruses comprise an exogenous nucleic acid. Infection of a host cell with a recombinant YFV provides for expression of the exogenous nucleic acid in a host cell and production of an antigenic polypeptide encoded by the exogenous nucleic acid. Such recombinant YFV are useful in eliciting an immune response to the exogenous polypeptide.
    Type: Grant
    Filed: March 6, 2003
    Date of Patent: May 17, 2005
    Assignee: The Regents of the University of California
    Inventors: Raul Andino-Pavlovsky, Andres McAllister-Moreno
  • Recombinant yellow fever virus and methods of use thereof
    Publication number: 20030157128
    Abstract: The present invention provides recombinant yellow fever viruses (YFV), particularly live attenuated recombinant YFV, which comprise exogenous ( i.e., non-YFV) nucleotide sequences which encode exogenous (i.e., non-YFV) amino acid sequences. These recombinant YFV viruses comprise an exogenous nucleic acid. Infection of a host cell with a recombinant YFV provides for expression of the exogenous nucleic acid in a host cell and production of an antigenic polypeptide encoded by the exogenous nucleic acid. Such recombinant YFV are useful in eliciting an immune response to the exogenous polypeptide.
    Type: Application
    Filed: March 6, 2003
    Publication date: August 21, 2003
    Inventors: Raul Andino-Pavlovsky, Andres McAllister-Moreno
  • Recombinant yellow fever virus and method of use thereof
    Patent number: 6589531
    Abstract: The present invention provides recombinant yellow fever viruses (YFV), particularly live attenuated recombinant YFV, which comprise exogenous (i.e., non-YFV) nucleotide sequences which encode exogenous (i.e., non-YFV) amino acid sequences. These recombinant YFV viruses comprise an exogenous nucleic acid. Infection of a host cell with a recombinant YFV provides for expression of the exogenous nucleic acid in a host cell and production of an antigenic polypeptide encoded by the exogenous nucleic acid. Such recombinant YFV are useful in eliciting an immune response to the exogenous polypeptide.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: July 8, 2003
    Assignee: The Regents of the University of California
    Inventors: Raul Andino-Pavlovsky, Andres McAllister-Moreno