Patents by Inventor Andres Muro

Andres Muro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS OF OTC CONSTRUCTS AND VECTORS
    Publication number: 20200038462
    Abstract: Provided herein are methods and compositions related to nucleic acids encoding ornithine transcarbamylase (OTC), such as nucleic acids comprising an OTC codon-optimized sequence, as well as related vectors, such as AAV vectors. Also, provided are methods for administering AAV vectors that comprise a sequence that encodes an enzyme associated with an urea cycle disorder and an expression control sequence, in combination with synthetic nanocarriers coupled to an immunosuppressant.
    Type: Application
    Filed: July 16, 2019
    Publication date: February 6, 2020
    Applicant: Selecta Biosciences, Inc.
    Inventors: Peter Keller, Takashi Kei Kishimoto, Andres Muro, Giulia De Sabbata
  • Treatment of hyperbilirubinemia
    Patent number: 10471132
    Abstract: The invention relates to a nucleic acid sequence useful in the treatment of hyperbilirubinemia, in particular in the treatment of Crigler-Najjar syndrome. More particularly, the nucleic acid sequence of the present invention is a codon-optimized UGT1A1 coding sequence.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: November 12, 2019
    Assignees: GENETHON, INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY
    Inventors: Federico Mingozzi, Giuseppe Ronzitti, Fanny Collaud, Andrés Muro, Giulia Bortolussi