Abstract: An adhesive composition includes one or more polymerizable cyanoacrylate monomers, a polymerization initiator and a polymerization accelerator for the one or more polymerizable cyanoacrylate monomers. A system for treating living tissue includes a first reservoir containing one or more polymerizable cyanoacrylate monomers, a second reservoir in a non-contacting relationship with the first reservoir containing a polymerization initiator and accelerator for the one or more polymerizable cyanoacrylate monomers, and an applicator capable of combining the polymerizable cyanoacrylate monomer and the polymerization initiator and accelerator to form an adhesive composition and then applying the adhesive composition to living tissue. The initiator may be a quaternary ammonium salt, and the accelerator may be a trihydroxy tertiary amine.

Abstract: An adhesive composition includes one or more polymerizable cyanoacrylate monomers, a polymerization initiator and a polymerization accelerator for the one or more polymerizable cyanoacrylate monomers. A system for treating living tissue includes a first reservoir containing one or more polymerizable cyanoacrylate monomers, a second reservoir in a non-contacting relationship with the first reservoir containing a polymerization initiator and accelerator for the one or more polymerizable cyanoacrylate monomers, and an applicator capable of combining the polymerizable cyanoacrylate monomer and the polymerization initiator and accelerator to form an adhesive composition and then applying the adhesive composition to living tissue. The initiator may be a quaternary ammonium salt, and the accelerator may be a trihydroxy tertiary amine.

Abstract: A method of treating or preventing tinea pedis, commonly known as Athlete's Foot, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea pedis, optionally with at least one of an additional anti-fungal agent or a foot care additive, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.

Abstract: An applicator for dispensing a polymerizable or cross-linkable material includes an outer container, an inner container disposed within the outer container and containing a polymerizable or cross-linkable material, and a rate modifier for the polymerizable or cross-linkable material coated on an outer surface of the inner container. The rate modifier modifies a polymerization or cross-linking rate when the polymerizable or cross-linkable monomer material contacts the rate modifier upon opening of the inner container. The polymerizable and/or cross-linkable material may be applied to a variety of substrates.

Abstract: A method of sterilizing a polymerizable monomeric adhesive composition includes: providing a polymerizable monomeric adhesive composition in a container, the polymerizable monomeric adhesive composition including a polymerizable 1,1-disubstituted ethylene monomer and at least one stabilizer; holding the composition in the container for a pre-determined amount of time, which is sufficient to inhibit or eliminate polymerization of the monomer during or immediately after sterilization, before sterilizing the composition; and sterilizing the polymerizable monomeric adhesive composition inside the container.

Abstract: An applicator for dispensing compositions includes a crushable ampoule covered with a barrier material that serves as a protective barrier. The applicator can also include a body made of a flexible material that holds at least one crushable ampoule. The protective barrier protects the user's fingers from puncture by shards created during breakage of the crushable ampoule.

Abstract: A combination includes a pipette-shaped container formed from a polymeric material selected from polyethylene terephthalate, high density polyethylene, low density polyethylene, and mixtures thereof, and a 1,1 -disubstituted ethylene monomer adhesive composition sealed in the pipette-shaped container prior to dispensing the material.

Abstract: A method of treating or preventing tinea pedis, commonly known as Athlete's Foot, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea pedis, optionally with at least one of an additional anti-fungal agent or a foot care additive, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.

Abstract: An applicator for dispensing compositions includes a crushable ampoule covered with a barrier material that serves as a protective barrier. The applicator can also include a body made of a flexible material that holds at least one crushable ampoule. The protective barrier protects the user's fingers from puncture by shards created during breakage of the crushable ampoule.

Abstract: A method of sterilizing a polymerizable monomeric adhesive composition includes: providing a polymerizable monomeric adhesive composition in a container, the polymerizable monomeric adhesive composition including a polymerizable 1,1 -disubstituted ethylene monomer and at least one stabilizer; holding the composition in the container for a pre-determined amount of time, which is sufficient to inhibit or eliminate polymerization of the monomer during or immediately after sterilization, before sterilizing the composition; and sterilizing the polymerizable monomeric adhesive composition inside the container.

Abstract: An applicator for dispensing compositions includes a crushable ampoule covered with a barrier material that serves as a protective barrier. The applicator can also include a body made of a flexible material that holds at least one crushable ampoule. The protective barrier protects the user's fingers from puncture by shards created during breakage of the crushable ampoule.

Abstract: Treatment methods for glass medical adhesive applicators in which a glass applicator is exposed to ammonium sulfate, an acidic gas, a plasma or a silanizing agent in order to remove or coat alkalide materials trapped in the glass.