Abstract: A customized Internet content distribution system comprises a storage of home web pages, wherein each web page is associated on the one hand to a segment identifier and on the other hand to a web page address, some of the web pages being associated to the same web page address such that each of these web pages defines a customized version of a generic web page associated to said same web page address, a web server arranged to receive a generic query for accessing a web page, said query being emitted from a device connected to the Internet, comprising a web page address fitted with a footprint of said device, to determine a segment identifier associated to said footprint, and to access said storage to obtain and send back to said device a web page associated to said web page address of the generic query and to said segment identifier.

Abstract: Provided are methods relating to the treatment of cancer with a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101 in combination with an inhibitor of the tryptophan metabolism pathway, e.g., an indoleamine-2,3-dioxygenase (IDO) inhibitor or a tryptophan-2, 3-dioxygenase (TDO) inhibitor.