Abstract: A process for separating a mixture of materials using a segregation media within a vessel having a central baffle structure which shuggles the mixture by oscillating the baffle structure at a frequency and amplitude. The mixture of materials may have overlapping densities with the segregation media having a density within the overlapping region. Polymers PE and PP may be separated in flake form. For a mixture of materials of differing densities, water may be the segregation media. Shuggling is combined with controlling the flow of water through the vessel at a set velocity. Embodiments are described for separating plastics and mineral ore.

Abstract: The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1 nm and about 25 nm, between about 1 nm and about 15 nm, or between about 1 nm and about 8 nm. The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound. The nanoparticle also exhibits high biostability and biocompatibility. To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as poly(ethylene glycol) (PEG). The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo.

Abstract: The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1 nm and about 25 nm, between about 1 nm and about 15 nm, or between about 1 nm and about 8 nm. The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound. The nanoparticle also exhibits high biostability and biocompatibility. To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as poly(ethylene glycol) (PEG). The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo.

Abstract: A heat exchanger assembly, comprising: heat exchanger pipework which comprises a plurality of elongate tube elements which extend in spaced relation and a plurality of pipe end couplings which fluidly connect open ends of respective tube elements, wherein the pipe end couplings each comprise a main body part to which the open ends of the respective tube elements are fixed, and an enclosure part which is fixed to the main body part and provides a closed fluid connection between the open ends of the respective tube elements; and a plurality of fins which extend in spaced relation and optionally substantially orthogonally to the tube elements, wherein the fins each comprise a sheet element, optionally a single, continuous sheet element, which includes a plurality of apertures through which extend respective ones of the tube elements, and a plurality of fin coupling elements which are located within respective ones of the fin apertures to interface the tube elements to the sheet elements.

Abstract: The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1 nm and about 25 nm, between about 1 nm and about 15 nm, or between about 1 nm and about 8 nm. The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound. The nanoparticle also exhibits high biostability and biocompatibility. To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as poly(ethylene glycol) (PEG). The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo.

Abstract: The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1 nm and about 25 nm, between about 1 nm and about 15 nm, or between about 1 nm and about 8 nm. The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound. The nanoparticle also exhibits high biostability and biocompatibility. To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as poly(ethylene glycol) (PEG). The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo.

Abstract: A process for separating a mixture of materials using a segregation media within a vessel having a central baffle structure which shuggles the mixture by oscillating the baffle structure at a frequency and amplitude. The mixture of materials may have overlapping densities with the segregation media having a density within the overlapping region. Polymers PE and PP may be separated in flake form. For a mixture of materials of differing densities, water may be the segregation media. Shuggling is combined with controlling the flow of water through the vessel at a set velocity. Embodiments are described for separating plastics and mineral ore.

Abstract: Systems and methods are provided for managing, optimizing subject information, recommending ophthalmologic assessments, and performing diagnostic assessments. The system includes a computing device having an image-capturing device and a display. The system includes a computer application that is executable on the computing device and operable to receive information regarding a subject, recommend ophthalmologic tests based on the information received, and perform ophthalmologic assessments on a subject. Performance of the ophthalmologic assessments causes the application to generate information regarding the ophthalmologic health of the subject, analyze the information generated, and present results of the analysis on the display.

Abstract: The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as polyethylene glycol) (PEG) The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo The nanoparticle may further be conjugated to a ligand capable of binding to a cellular component associated with the specific cell type, such as a tumor marker A therapeutic agent may be attached to the nanoparticle Radionuclides/radiometals or paramagnetic ions may be conjugated to the nanoparticle to permit the nanoparticle to be detectable by various imaging techniques.

Abstract: An investment casting process for a hollow component such as a gas turbine blade utilizing a ceramic core (10) that is cast in a flexible mold (24) using a low pressure, vibration assisted casting process. The flexible mold is cast from a master tool (14) machined from soft metal using a relatively low precision machining process, with relatively higher precision surfaces being defined by a precision formed insert (22) incorporated into the master tool. A plurality of identical flexible molds may be formed from a single master tool in order to permit the production of ceramic cores at a desired rate with a desired degree of part-to-part precision.

Abstract: In a wireless media network a source device provides entertainment content to a sink device over a radio frequency (RF) wireless channel. The source device can go into a receive only quiet enrolment mode until activated by a sink device transmitting enrolment trigger packets or having a signal strength above a certain threshold, thereby improving coexistence with other wireless devices. The source device changes from the quiet enrolment mode to an active enrolment mode when activated by the sink device.

Abstract: A heat exchanger assembly, comprising: heat exchanger pipework which comprises a plurality of elongate tube elements which extend in spaced relation and a plurality of pipe end couplings which fluidly connect open ends of respective tube elements, wherein the pipe end couplings each comprise a main body part to which the open ends of the respective tube elements are fixed, and an enclosure part which is fixed to the main body part and provides a closed fluid connection between the open ends of the respective tube elements; and a plurality of fins which extend in spaced relation and optionally substantially orthogonally to the tube elements, wherein the fins each comprise a sheet element, optionally a single, continuous sheet element, which includes a plurality of apertures through which extend respective ones of the tube elements, and a plurality of fin coupling elements which are located within respective ones of the fin apertures to interface the tube elements to the sheet elements.

Abstract: A steam generator for generating a superheated fluid from a working fluid using a stream of heated gas, the steam generator comprising: a housing, which defines a gas flow path having an inlet at one, upstream end thereof into which a stream of heated gas is delivered and an outlet at the other, downstream end thereof; and a steam generation module which is disposed within the gas flow path of the housing, the steam generation module comprising a heat exchanger which receives a working fluid and is operative to raise the temperature of the working fluid to provide a saturated fluid, and a superheater which receives the saturated fluid from the heat exchanger and is operative to raise the temperature of the saturated fluid and provide a supersaturated fluid.

Abstract: The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1 nm and about 25 nm, between about 1 nm and about 15 nm, or between about 1 nm and about 8 nm. The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound. The nanoparticle also exhibits high biostability and biocompatibility. To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as poly(ethylene glycol) (PEG). The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo.

Abstract: Articles for recording a holographic image are described. The articles include a holographic recording medium having a plurality of surfaces, having a transparent polymeric binder and a photochemically active dye, the holographic recording medium having a holographic image recorded therein formed by exposed areas of the photochemically active dye and unexposed areas of the photochemically active dye; and a first light-blocking layer or material over a first surface of the holographic recording medium from which surface the holographic image is viewed, the light blocking layer or material absorbing light in the wavelength range to which the photochemically active dye is sensitive and allowing transmission of light in a different wavelength range for viewing the holographic image.

Abstract: Articles for recording a holographic image are described. The articles include a holographic recording medium having a plurality of surfaces, having a transparent polymeric binder and a photochemically active dye, the holographic recording medium having a holographic image recorded therein formed by exposed areas of the photochemically active dye and unexposed areas of the photochemically active dye; and a first light-blocking layer or material over a first surface of the holographic recording medium from which surface the holographic image is viewed, the light blocking layer or material absorbing light in the wavelength range to which the photochemically active dye is sensitive and allowing transmission of light in a different wavelength range for viewing the holographic image.

Abstract: A method of making a hologram includes recording a first hologram in a holographic recording medium at a first deformation ratio; changing the first deformation ratio to a second deformation ratio that is different from the first deformation ratio; and recording a second hologram in the holographic recording medium at the second deformation ratio to form a recorded holographic medium.

Abstract: A method is described for recording a volume reflection holographic image that is viewable when illuminated by light at a wavelength Wv.

Abstract: A method of manufacturing an article for display of a holographic image is described that includes thermally fusing a holographic recording medium containing a photochemically active dye dispersed in a transparent thermoplastic polymer binder to another layer or material; and then exposing the holographic film to intersecting beams of coherent light to form a holographic image therein formed by photoreacted areas of the photochemically active dye and unreacted areas of the photochemically active dye.

Abstract: A method of recording a volume holographic image is described in which a holographic recording medium containing a photoreactive dye is exposed to a plurality of coherent light sources emitting at a wavelength to which the dye is sensitive, thereby forming an interference fringe pattern therein. The photoreaction occurring in the areas of constructive interference generates a periodic array of photoreacted areas of the dye and unreacted areas of the dye. This generated interference fringe pattern may contain, but does not have to contain any image or other encoded information. Selected areas of the interference fringe pattern are then exposed to actinic radiation in such a manner to partially or fully bleach, remove, or deactivate the photoreactive dye fringe pattern, thereby producing a holographic pattern, shape, or image formed by areas of the interference fringe pattern that were not bleached, removed, or deactivated.