Abstract: A method includes receiving training data that includes a plurality of sets of text-to-speech (TTS) spoken utterances each associated with a respective language and including TTS utterances of synthetic speech spoken that includes a corresponding reference speech representation paired with a corresponding input text sequence. For each TTS utterance in each set of the TTS spoken training utterances of the received training data, the method includes generating a corresponding TTS encoded textual representation for the corresponding input text sequence, generating a corresponding speech encoding for the corresponding TTS utterance of synthetic speech, generating a shared encoder output, generating a predicted speech representation for the corresponding TTS utterance of synthetic speech, and determining a reconstruction loss. The method also includes training a TTS model based on the reconstruction losses determined for the TTS utterances in each set of the TTS spoken training utterances.

Abstract: Systems and methods for identifying a likelihood that a reservoir of a geological formation received a secondary charge of hydrocarbons of relatively very different thermal maturity of composition are provided. One method includes positioning a downhole acquisition tool in a wellbore in a geological formation and testing one or more fluid properties of the formation fluid. Data processing circuitry may identify whether a relationship of the one or more fluid properties exceeds a first threshold that indicates likely asphaltene instability. When this is the case, data processing circuitry may be used to model the geological formation using a realization scenario in which multiple charges of hydrocarbons of substantially different thermal maturity or substantially different composition, or both, filled a reservoir of the geological formation over geologic time.

Abstract: Compounds of Formula (I): wherein R1, R3, R11, R12, X, Y1, Y2, Y3, Y4 and are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring anti-apoptotic inhibitors.

Abstract: A patient interface including a plenum chamber, a first seal-forming structure for forming a seal around the patient's mouth, and a second seal-forming structure for forming a seal around the patient's nares. The patient interface further includes at least one stopper rib disposed in the cavity of the plenum chamber spaced apart from the first seal-forming structure in a rest position. The first seal-forming structure configured to contact the at least one stopper rib in an operational position. The at least one stopper rib configured to oppose compression of the first seal-forming structure in an anterior direction. The second seal-forming structure is not configured to contact the at least one stopper rib.

Abstract: The present disclosure generally relates to underwater user interfaces.

Abstract: Provided herein is a disinfecting device including a container containing a chlorhexidine-based solution having a chlorhexidine concentration of from 0.2-2.0% wt/vol. Provided also is a medical connector disinfected with the disinfecting device. A method of disinfecting a medical connector using the disinfecting device is also disclosed.

Abstract: A laser crafting apparatus for directing electromagnetic radiation toward a workpiece may include various features. For example, the laser crafting apparatus may include a material support tray that is removably supported within an internal volume of the laser crafting apparatus. Further, the apparatus may include pre-filter disposed in a ventilation pathway between a workspace region of the internal volume and an extractor fan. The laser crafting apparatus may include a laser carriage assembly that houses a laser module and the assembly may include a lens tray detachably coupled to the support structure of the laser carriage assembly. In various embodiments, the laser crafting apparatus includes a lid having a radiation attenuation layer and a fire suppression layer.

Abstract: In one example, a method comprises: exposing a first photodiode to incident light to generate first charge; exposing a second photodiode to the incident light to generate second charge; converting, by a first charge sensing unit, the first charge to a first voltage; converting, by a second charge sensing unit, the second charge to a second voltage; controlling an ADC to detect, based on the first voltage, that a quantity of the first charge reaches a saturation threshold, and to measure a saturation time when the quantity of the first charge reaches the saturation threshold; stopping the exposure of the first photodiode and the second photodiode to the incident light based on detecting that the quantity of the first charge reaches the saturation threshold; and controlling the ADC to measure, based on the second voltage, a quantity of the second charge generated by the second photodiode before the exposure ends.

Abstract: In some implementations, a plurality of thermoelectric devices may be arranged to cool one or more components of a downhole drilling component during drilling operations. A current can be applied to one or more thermoelectric devices to generate a cooling effect. The thermoelectric devices can be located and arranged so that they cool some or all of a bottom hole assembly or components thereof, such as one or more sensors, batteries, processors, electrics, and the like. The thermoelectric devices also may be located and arranged to cool sensors, batteries, other downhole components, and/or drilling mud in a wellbore during drilling operations. A plurality of thermoelectric devices may be used to generate electric power downhole from a temperature difference. The electric power may be used to power sensors, processors, charge batteries, and be used by one or more downhole electric components, such as those in a bottom hold assembly.

Abstract: In some implementations, a plurality of thermoelectric devices may be arranged to cool one or more components of a downhole drilling component during drilling operations. A current can be applied to one or more thermoelectric devices to generate a cooling effect. The thermoelectric devices can be located and arranged so that they cool some or all of a bottom hole assembly or components thereof, such as one or more sensors, batteries, processors, electrics, and the like. The thermoelectric devices also may be located and arranged to cool sensors, batteries, other downhole components, and/or drilling mud in a wellbore during drilling operations. A plurality of thermoelectric devices may be used to generate electric power downhole from a temperature difference. The electric power may be used to power sensors, processors, charge batteries, and be used by one or more downhole electric components, such as those in a bottom hold assembly.

Abstract: Disclosed are quinoline and quinazoline compounds which modulate the activity of the gated ion channels. Compounds that modulate these gated ion channels are useful in the treatment of diseases and disorders related to pain, inflammation, the neurological system, the gastrointestinal system and genitourinary system. Preferred compounds include quinoline or quinazoline derivatives substituted at the 4-position via N(H), C(O) or O moieties.

Abstract: The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.

Abstract: A system to augment the collected odometer data points with more precise location data which provides an indication of a location of a vehicle associated with the odometer at a given time, such as Global Positioning System (GPS) GPS data points. Additionally, the GPS data points may be collected at a higher sampling rate than the odometer data points, thus providing a more precise indication of a distance traveled by a vehicle at any given time.

Abstract: A variable current trans-impedance amplifier (TIA) for an ultrasound device is described. The TIA may be coupled to an ultrasonic transducer to amplify an output signal of the ultrasonic transducer representing an ultrasound signal received by the ultrasonic transducer. During acquisition of the ultrasound signal by the ultrasonic transducer, one or more current sources in the TIA may be varied.

Abstract: The present disclosure generally provides compounds that antagonize certain T2R taste receptors, including related uses, methods, and compositions for the reduction of bitter taste and/or the enhancement of sweet taste. In certain aspects, the disclosure provides flavored articles or flavored compositions comprising such compounds, as well as uses of such compounds to reduce the bitter taste and/or enhance the sweet taste of such flavored articles or flavored compositions.

Abstract: A projector sequentially generates light pulses to form a sparse grid array. The light pulses reflect off objects in an environment and are reflected towards a sensor array. The sensor array sequentially senses the reflected light pulses across pixels of the sensor array. A depth sensing system calculates depth information of objects in the environment based on the sequential nature of the pulse generation and the pulse sensing. The depth sensing system calculates depth information based on both the positional and temporal information of generated light pulses, and the positional and temporal information of sensed light pulses. The depth sensing system may generate a representation of the environment based on the depth information.

Abstract: A method of forming a uniaxially oriented crystalline polymer article includes heating a segment of a crystallizable polymer article to a first temperature, applying a stress to the crystallizable polymer article in an amount effective to induce a positive strain within the segment of the crystallizable polymer article, and heating the segment of the crystallizable polymer article to a second temperature greater than the first temperature while continuing to apply the stress.

Abstract: In one example, an apparatus comprises: a first photodiode to generate a first charge; a second photodiode to generate a second charge; a quantizer; a first memory bank and a second memory bank; and a controller configured to: control the quantizer to perform a first quantization operation and a second quantization operation of the first charge to generate, respectively, a first digital output and a second digital output, the first and second quantization operations being associated with different intensity ranges; store one of the first digital output or the second digital output in the first memory bank; control the quantizer to perform a third quantization operation of the second charge to generate a third digital output, the third quantization operation being associated with a different intensity range from at least one of the first or second quantization operations; and store the third digital output in the second memory bank.

Abstract: Embodiments described herein relate to flat optical devices with a coating layer including monolayers selected from the group consisting of molybdenum disulfide (MoS2), tungsten disulfide (WS2), tungsten diselenide (WSe2), molybdenum diselenide (MoSe2), molybdenum ditelluride (MoTe2), titanium disulfide (TlS2), zirconium disulfide (ZrS2), zirconium diselenide (ZrSe2), hafnium disulfide (HfS2), platinum disulfide (PtS2), tin disulfide (SnS2), or combinations thereof. The coating layer is disposed over a plurality of optical device structures of the optical device. The monolayers may alternate between the materials to form the coating layer or may be a uniform coating layer of a single material. The coating layer is disposed over each optical device structure of the plurality of optical device structures.