Abstract: A reduced-friction screw is described. The screw requires less turning torque than a conventional screw to drive it into a workpiece. The shaft of the screw has a reduced-thickness thread that produces less sliding friction than a conventional screw having thread of the same depth and pitch. In addition, the holding ability of the reduced-friction screw is substantially the same as a conventional screw having thread of the same pitch and depth. Another embodiment contains a shaft having a reduced diameter, to further reduce sliding friction. Yet another embodiment contains a segmented, reduced-thickness thread that resists removal and loosening when the workpiece is subject to twisting, vibration, or warping. To prevent loosening of the reduced-friction screw, the bottom of the screw head may contain protrusions to increase the frictional contact of the head with the workpiece.