Patents by Inventor Andrew B. Cubitt

Andrew B. Cubitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Long wavelength engineered fluorescent proteins
    Patent number: 6403374
    Abstract: Engineered fluorescent proteins, nucleic acids encoding them and methods of use are provided.
    Type: Grant
    Filed: December 16, 1999
    Date of Patent: June 11, 2002
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, S. James Remington, Andrew B. Cubitt, Roger Heim, Mats F. Ormö
  • Assays for protein kinases using fluorescent protein substrates
    Publication number: 20020061546
    Abstract: This invention provides assays for protein kinase activity using fluorescent proteins engineered to include sequences that can be phosphorylated by protein kinases. The proteins exhibit different fluorescent properties in the non-phosphorylated and phosphorylated states.
    Type: Application
    Filed: June 19, 2001
    Publication date: May 23, 2002
    Applicant: The Regents of the University of California
    Inventors: Roger Y. Tsien, Andrew B. Cubitt
  • Assays for protein kinases using fluorescent protein substrates
    Patent number: 6248550
    Abstract: This invention provides assays for protein kinase activity using fluorescent proteins engineered to include sequences that can be phosphorylated by protein kinases. The proteins exhibit different fluorescent properties in the non-phosphorylated and phosphorylated states.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: June 19, 2001
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, Andrew B. Cubitt
  • Long wavelength engineered fluorescent proteins
    Patent number: 6124128
    Abstract: Engineered fluorescent proteins, nucleic acids encoding them and methods of use.
    Type: Grant
    Filed: August 30, 1996
    Date of Patent: September 26, 2000
    Assignees: The Regents of the University of California, Aurora Biosciences, The University of Oregon
    Inventors: Roger Y. Tsien, Andrew B. Cubitt, Roger Heim, Mats F. Ormo, S. James Remington
  • Long wavelength engineered fluorescent proteins
    Patent number: 6077707
    Abstract: This invention provides functional engineered fluorescent proteins with varied fluorescence characteristics that can be easily distinguished from currently existing green and blue fluorescent proteins. In one aspect, the invention provides nucleic acids, expression vectors and recombinant host cells comprising nucleotide sequences encoding functional engineered fluorescent proteins comprising aromatic substitutions at position 66 and a folding mutation. In one embodiment the invention provides for fluorescent proteins containing an aromatic substitution at Thr 203.
    Type: Grant
    Filed: November 19, 1997
    Date of Patent: June 20, 2000
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, S. James Remington, Andrew B. Cubitt, Roger Heim, Mats F. Ormo
  • Long wavelength engineered fluorescent proteins
    Patent number: 6054321
    Abstract: This invention provides functional engineered fluorescent proteins with varied fluorescence characteristics that can be easily distinguished from currently existing green and blue fluorescent proteins. In one embodiment the invention provides for the three dimensional structure and atomic coordinates of an Aequorea green fluorescent protein and methods for their use. In one embodiment, this invention provides a computational method of modeling the three dimensional structure of any other fluorescent protein based on the three dimensional structure of an Aequorea green fluorescent protein.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: April 25, 2000
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, S. James Remington, Andrew B. Cubitt, Roger Heim, Mats F. Ormo
  • Photochromic fluorescent proteins and optical memory storage devices based on fluorescent proteins
    Patent number: 6046925
    Abstract: Photochromic fluorescent protein moiety having two or more stable states having excitation or emission spectra that are shifted from one wavelength region to another wavelength region in the two states are described. The photochromic material switches between states by irradiation with light of appropriate wavelengths. The two states are preferably stable at room temperature and in the dark. The switching between states can be reversible.
    Type: Grant
    Filed: April 14, 1997
    Date of Patent: April 4, 2000
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, Roger Heim, Andrew B. Cubitt, Robert M. Dickson, William E. Moerner
  • Assays for protein kinases using fluorescent protein substrates
    Patent number: 5925558
    Abstract: This invention provides assays for protein kinase activity using fluorescent proteins engineered to include sequences that can be phosphorylated by protein kinases. The proteins exhibit different fluorescent properties in the non-phosphorylated and phosphorylated states.
    Type: Grant
    Filed: July 16, 1996
    Date of Patent: July 20, 1999
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, Andrew B. Cubitt
  • Assays for protein kinases using fluorescent
    Patent number: 5912137
    Abstract: This invention provides assays for protein kinase activity using fluorescent proteins engineered to include sequences that can be phosphorylated by protein kinases. The proteins exhibit different fluorescent properties in the non-phosphorylated and phosphorylated states.
    Type: Grant
    Filed: July 16, 1996
    Date of Patent: June 15, 1999
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, Andrew B. Cubitt