Patents by Inventor Andrew B. Dennis

Andrew B. Dennis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABLE PHARMACEUTICAL COMPOSITION FOR OPTIMIZED DELIVERY OF AN HIV ATTACHMENT INHIBITOR
    Publication number: 20150158891
    Abstract: A pharmaceutical composition contains the compound 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine, and hydroxypropyl methyl cellulose (HPMC) having a viscosity of at least about 100 cP, wherein the composition does not contain any enzyme inhibitors.
    Type: Application
    Filed: December 11, 2014
    Publication date: June 11, 2015
    Inventors: Jonathan R. Brown, Helen Hughes, Andrew B. Dennis, Peter Timmins
  • STABLE PHARMACEUTICAL COMPOSITION FOR OPTIMIZED DELIVERY OF AN HIV ATTACHMENT INHIBITOR
    Publication number: 20100056540
    Abstract: A pharmaceutical composition contains the compound 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine, and hydroxypropyl methyl cellulose (HPMC) having a viscosity of at least about 100 cP, wherein the composition does not contain any enzyme inhibitors.
    Type: Application
    Filed: September 3, 2009
    Publication date: March 4, 2010
    Inventors: Jonathan R. Brown, Helen Toale, Andrew B. Dennis, Peter Timmins
  • Method of use of a biphasic controlled release delivery system for high solubility pharmaceuticals and method
    Patent number: 6660300
    Abstract: A biphasic controlled release delivery system for pharmaceuticals which have high water solubility, such as the antidiabetic metformin HCl salt, is provided which provides a dosage form that has prolonged gastric residence so that a dosing regimen of at least one gram metformin, once daily, may be achieved while providing effective control of plasma glucose.
    Type: Grant
    Filed: August 21, 2002
    Date of Patent: December 9, 2003
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Peter Timmins, Andrew B. Dennis, Kiren A. Vyas
  • Biphasic controlled release delivery system for high solubility pharmaceuticals and method
    Patent number: 6475521
    Abstract: A biphasic controlled release delivery system for pharmaceuticals which have high water solubility, such as the antidiabetic metformin HCl salt, is provided which provides a dosage form that has prolonged gastric residence so that a dosing regimen of at least one gram metformin, once daily, may be achieved while providing effective control of plasma glucose.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: November 5, 2002
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Peter Timmins, Andrew B. Dennis, Kiren A. Vyas
  • Nefazodone dosage form
    Patent number: 6143325
    Abstract: Extended-release nefazodone compositions containing nefazodone hydrochloride, ionic and non-ionic gelling polymers, an insoluble hydrophilic agent, and optional pharmaceutically acceptable excipients demonstrate pH-modulated release of nefazodone. These compositions are formulated into unit dosage forms for improved oral administration. The improvements comprise an extended drug release profile providing comparative levels of nefazodone with respect to immediate release dosage forms and, additionally, demonstrating the lack of a food effect.
    Type: Grant
    Filed: April 26, 1999
    Date of Patent: November 7, 2000
    Assignee: Bristol-Myers Squibb Company
    Inventors: Andrew B. Dennis, Peter Timmins, Alison C. Hodsdon
  • Solid pharmaceutical dosage form and a method for reducing abrasion
    Patent number: 5436011
    Abstract: A method for reducing abrasion during film coating of susceptible solid dosage forms by applying to an uncoated dosage form, a subcoat containing a pharmaceutically acceptable polyalkylene glycol and the resulting solid pharmaceutical dosage form.
    Type: Grant
    Filed: April 16, 1993
    Date of Patent: July 25, 1995
    Assignee: Bristol-Myers Squibb Company
    Inventors: Andrew B. Dennis, David L. McCann, Alexander P. Green
  • Tablet composition and method for problem pharmaceutical materials using citric acid
    Patent number: 5137730
    Abstract: In accordance with the present invention an improved tablet composition for drugs or active ingredients prone to poor tabletting properties is disclosed. The improved composition comprises a premixture, consisting essentially of between about 85 and 99.9 percent by weight of the active ingredient and between about 0.1 and 15 percent by weight of citric acid, and one or more other formulation ingredients added to premixture. The present invention also involves the process for making such compositions and products therefrom.
    Type: Grant
    Filed: May 28, 1991
    Date of Patent: August 11, 1992
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Andrew B. Dennis, Peter Timmins, Himadri Sen